{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1567
    },
    {
      "term": "OFF LABEL USE",
      "count": 1187
    },
    {
      "term": "DRUG INTERACTION",
      "count": 1074
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 754
    },
    {
      "term": "NAUSEA",
      "count": 671
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 618
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 594
    },
    {
      "term": "PYREXIA",
      "count": 590
    },
    {
      "term": "VOMITING",
      "count": 493
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 459
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 430
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 422
    },
    {
      "term": "PARADOXICAL DRUG REACTION",
      "count": 416
    },
    {
      "term": "RASH",
      "count": 412
    },
    {
      "term": "DYSPNOEA",
      "count": 407
    },
    {
      "term": "DIARRHOEA",
      "count": 404
    },
    {
      "term": "COUGH",
      "count": 381
    },
    {
      "term": "FATIGUE",
      "count": 360
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 345
    },
    {
      "term": "PRURITUS",
      "count": 335
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 318
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 303
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 293
    },
    {
      "term": "TUBERCULOSIS",
      "count": 272
    },
    {
      "term": "MYCOBACTERIUM AVIUM COMPLEX INFECTION",
      "count": 269
    },
    {
      "term": "HEADACHE",
      "count": 262
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 255
    },
    {
      "term": "PAIN",
      "count": 247
    },
    {
      "term": "NEUTROPENIA",
      "count": 246
    },
    {
      "term": "ARTHRALGIA",
      "count": 244
    },
    {
      "term": "ANAEMIA",
      "count": 237
    },
    {
      "term": "ASTHENIA",
      "count": 229
    },
    {
      "term": "PNEUMONIA",
      "count": 228
    },
    {
      "term": "DECREASED APPETITE",
      "count": 221
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME",
      "count": 213
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 210
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 209
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 208
    },
    {
      "term": "DIZZINESS",
      "count": 208
    },
    {
      "term": "MALAISE",
      "count": 205
    },
    {
      "term": "DEATH",
      "count": 202
    },
    {
      "term": "EOSINOPHILIA",
      "count": 198
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 194
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 190
    },
    {
      "term": "RENAL FAILURE",
      "count": 179
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 171
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 168
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 150
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 149
    },
    {
      "term": "HYPOTENSION",
      "count": 144
    },
    {
      "term": "PANCYTOPENIA",
      "count": 144
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 143
    },
    {
      "term": "PRODUCTIVE COUGH",
      "count": 142
    },
    {
      "term": "HYPERTENSION",
      "count": 140
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 133
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 132
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 131
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 130
    },
    {
      "term": "MYALGIA",
      "count": 129
    },
    {
      "term": "DRUG LEVEL DECREASED",
      "count": 126
    },
    {
      "term": "HIDRADENITIS",
      "count": 126
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 125
    },
    {
      "term": "ACUTE HEPATIC FAILURE",
      "count": 124
    },
    {
      "term": "LEUKOPENIA",
      "count": 123
    },
    {
      "term": "SEPSIS",
      "count": 123
    },
    {
      "term": "INSOMNIA",
      "count": 122
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 122
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 121
    },
    {
      "term": "HEPATITIS",
      "count": 120
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 120
    },
    {
      "term": "URTICARIA",
      "count": 120
    },
    {
      "term": "ANXIETY",
      "count": 117
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 117
    },
    {
      "term": "CHILLS",
      "count": 114
    },
    {
      "term": "HAEMOPTYSIS",
      "count": 113
    },
    {
      "term": "JAUNDICE",
      "count": 112
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 111
    },
    {
      "term": "DISSEMINATED TUBERCULOSIS",
      "count": 111
    },
    {
      "term": "ERYTHEMA",
      "count": 110
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 110
    },
    {
      "term": "TREATMENT NONCOMPLIANCE",
      "count": 109
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 108
    },
    {
      "term": "CHOLESTASIS",
      "count": 108
    },
    {
      "term": "INFECTION",
      "count": 108
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 108
    },
    {
      "term": "PULMONARY TUBERCULOSIS",
      "count": 107
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 106
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME ASSOCIATED TUBERCULOSIS",
      "count": 104
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 104
    },
    {
      "term": "BACK PAIN",
      "count": 100
    },
    {
      "term": "DYSPHONIA",
      "count": 100
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 100
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 100
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 99
    },
    {
      "term": "MYCOBACTERIAL INFECTION",
      "count": 99
    },
    {
      "term": "PANCREATITIS",
      "count": 99
    },
    {
      "term": "THERAPY INTERRUPTED",
      "count": 99
    },
    {
      "term": "SEIZURE",
      "count": 97
    },
    {
      "term": "FALL",
      "count": 96
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 96
    }
  ]
}