{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 327
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 179
    },
    {
      "term": "PYREXIA",
      "count": 140
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 138
    },
    {
      "term": "OFF LABEL USE",
      "count": 133
    },
    {
      "term": "NEUTROPENIA",
      "count": 124
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 117
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 113
    },
    {
      "term": "SEPSIS",
      "count": 105
    },
    {
      "term": "HYPOTENSION",
      "count": 88
    },
    {
      "term": "ANAEMIA",
      "count": 85
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 85
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 79
    },
    {
      "term": "RENAL FAILURE",
      "count": 78
    },
    {
      "term": "PNEUMONIA",
      "count": 76
    },
    {
      "term": "DYSPNOEA",
      "count": 70
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 68
    },
    {
      "term": "METHAEMOGLOBINAEMIA",
      "count": 62
    },
    {
      "term": "DIARRHOEA",
      "count": 59
    },
    {
      "term": "NAUSEA",
      "count": 59
    },
    {
      "term": "VOMITING",
      "count": 58
    },
    {
      "term": "DEATH",
      "count": 57
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 56
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 55
    },
    {
      "term": "PANCYTOPENIA",
      "count": 51
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 50
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 50
    },
    {
      "term": "HYPOXIA",
      "count": 50
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 49
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 48
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 45
    },
    {
      "term": "HAEMOLYTIC ANAEMIA",
      "count": 43
    },
    {
      "term": "INFECTION",
      "count": 39
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 38
    },
    {
      "term": "DISSEMINATED INTRAVASCULAR COAGULATION",
      "count": 37
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 37
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 37
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 36
    },
    {
      "term": "LEUKOPENIA",
      "count": 36
    },
    {
      "term": "BLOOD PHOSPHORUS INCREASED",
      "count": 34
    },
    {
      "term": "CARDIAC ARREST",
      "count": 34
    },
    {
      "term": "CONSTIPATION",
      "count": 34
    },
    {
      "term": "FATIGUE",
      "count": 34
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 34
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 33
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 31
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 31
    },
    {
      "term": "ASTHENIA",
      "count": 30
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 29
    },
    {
      "term": "HYPERPHOSPHATAEMIA",
      "count": 29
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 29
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 29
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 28
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 28
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 27
    },
    {
      "term": "HYPERTENSION",
      "count": 27
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 27
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 26
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 26
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 25
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 25
    },
    {
      "term": "CHEST PAIN",
      "count": 25
    },
    {
      "term": "HYPERTRIGLYCERIDAEMIA",
      "count": 25
    },
    {
      "term": "SOMNOLENCE",
      "count": 25
    },
    {
      "term": "COUGH",
      "count": 24
    },
    {
      "term": "DECREASED APPETITE",
      "count": 24
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 24
    },
    {
      "term": "HAEMOLYSIS",
      "count": 24
    },
    {
      "term": "HEPATOCELLULAR INJURY",
      "count": 24
    },
    {
      "term": "IMMUNE EFFECTOR CELL-ASSOCIATED NEUROTOXICITY SYNDROME",
      "count": 24
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 24
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 24
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 24
    },
    {
      "term": "NERVOUS SYSTEM DISORDER",
      "count": 24
    },
    {
      "term": "RASH",
      "count": 24
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 24
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 23
    },
    {
      "term": "DEHYDRATION",
      "count": 23
    },
    {
      "term": "HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS",
      "count": 23
    },
    {
      "term": "HYPERBILIRUBINAEMIA",
      "count": 23
    },
    {
      "term": "MALAISE",
      "count": 23
    },
    {
      "term": "NEUROTOXICITY",
      "count": 23
    },
    {
      "term": "TACHYCARDIA",
      "count": 23
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 22
    },
    {
      "term": "FEBRILE BONE MARROW APLASIA",
      "count": 22
    },
    {
      "term": "HEADACHE",
      "count": 22
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 22
    },
    {
      "term": "HYPERCALCAEMIA",
      "count": 22
    },
    {
      "term": "BLOOD URIC ACID INCREASED",
      "count": 21
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 21
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 21
    },
    {
      "term": "DIZZINESS",
      "count": 21
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 21
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 21
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 20
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 20
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 20
    },
    {
      "term": "HYPOFIBRINOGENAEMIA",
      "count": 20
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 20
    },
    {
      "term": "PAIN",
      "count": 20
    }
  ]
}