{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 3752
    },
    {
      "term": "OFF LABEL USE",
      "count": 3147
    },
    {
      "term": "FATIGUE",
      "count": 2700
    },
    {
      "term": "PAIN",
      "count": 2620
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 2146
    },
    {
      "term": "HEADACHE",
      "count": 2119
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 2114
    },
    {
      "term": "NAUSEA",
      "count": 2083
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 2050
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 2016
    },
    {
      "term": "VOMITING",
      "count": 1994
    },
    {
      "term": "RASH",
      "count": 1981
    },
    {
      "term": "DRUG INTERACTION",
      "count": 1917
    },
    {
      "term": "HYPERTENSION",
      "count": 1858
    },
    {
      "term": "DIZZINESS",
      "count": 1835
    },
    {
      "term": "DEPRESSION",
      "count": 1800
    },
    {
      "term": "PYREXIA",
      "count": 1776
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 1747
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 1741
    },
    {
      "term": "PEMPHIGUS",
      "count": 1725
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 1713
    },
    {
      "term": "ALOPECIA",
      "count": 1703
    },
    {
      "term": "DIARRHOEA",
      "count": 1701
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 1648
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 1647
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 1636
    },
    {
      "term": "JOINT SWELLING",
      "count": 1610
    },
    {
      "term": "GLOSSODYNIA",
      "count": 1605
    },
    {
      "term": "LIVER INJURY",
      "count": 1577
    },
    {
      "term": "WOUND",
      "count": 1572
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 1560
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 1560
    },
    {
      "term": "ARTHRALGIA",
      "count": 1538
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 1511
    },
    {
      "term": "PNEUMONIA",
      "count": 1492
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 1490
    },
    {
      "term": "ANXIETY",
      "count": 1481
    },
    {
      "term": "DYSPNOEA",
      "count": 1463
    },
    {
      "term": "ARTHROPATHY",
      "count": 1459
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 1442
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 1421
    },
    {
      "term": "PERICARDITIS",
      "count": 1403
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1394
    },
    {
      "term": "HAND DEFORMITY",
      "count": 1388
    },
    {
      "term": "SWELLING",
      "count": 1386
    },
    {
      "term": "OVERDOSE",
      "count": 1366
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 1345
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 1345
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 1340
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 1333
    },
    {
      "term": "PRESCRIBED OVERDOSE",
      "count": 1284
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 1280
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 1280
    },
    {
      "term": "WHEEZING",
      "count": 1268
    },
    {
      "term": "SYNOVITIS",
      "count": 1265
    },
    {
      "term": "MALAISE",
      "count": 1255
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1229
    },
    {
      "term": "ASTHENIA",
      "count": 1223
    },
    {
      "term": "DISCOMFORT",
      "count": 1221
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 1215
    },
    {
      "term": "INFECTION",
      "count": 1214
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 1212
    },
    {
      "term": "URTICARIA",
      "count": 1196
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 1195
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 1191
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 1191
    },
    {
      "term": "INSOMNIA",
      "count": 1184
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 1180
    },
    {
      "term": "SOMNOLENCE",
      "count": 1173
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 1154
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 1131
    },
    {
      "term": "PRURITUS",
      "count": 1130
    },
    {
      "term": "FIBROMYALGIA",
      "count": 1120
    },
    {
      "term": "ASTHMA",
      "count": 1110
    },
    {
      "term": "BLISTER",
      "count": 1108
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 1101
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 1085
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 1061
    },
    {
      "term": "STOMATITIS",
      "count": 1059
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 1058
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 1057
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 1044
    },
    {
      "term": "MUSCLE INJURY",
      "count": 1043
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 1041
    },
    {
      "term": "OEDEMA",
      "count": 1040
    },
    {
      "term": "FOLLICULITIS",
      "count": 1012
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 1000
    },
    {
      "term": "DRUG ABUSE",
      "count": 981
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 966
    },
    {
      "term": "INJURY",
      "count": 963
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 943
    },
    {
      "term": "CHEST PAIN",
      "count": 942
    },
    {
      "term": "CONTUSION",
      "count": 937
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 932
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 925
    },
    {
      "term": "FALL",
      "count": 924
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 923
    },
    {
      "term": "SEDATION",
      "count": 922
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 907
    },
    {
      "term": "SLEEP DISORDER",
      "count": 888
    }
  ]
}