{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 696
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 661
    },
    {
      "term": "PYREXIA",
      "count": 625
    },
    {
      "term": "DRUG INTERACTION",
      "count": 610
    },
    {
      "term": "PARADOXICAL DRUG REACTION",
      "count": 517
    },
    {
      "term": "OFF LABEL USE",
      "count": 512
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 498
    },
    {
      "term": "VOMITING",
      "count": 493
    },
    {
      "term": "TUBERCULOSIS",
      "count": 411
    },
    {
      "term": "NAUSEA",
      "count": 397
    },
    {
      "term": "ANAEMIA",
      "count": 380
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 367
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 361
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 330
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 281
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME",
      "count": 265
    },
    {
      "term": "HEPATITIS",
      "count": 263
    },
    {
      "term": "JAUNDICE",
      "count": 258
    },
    {
      "term": "ACUTE HEPATIC FAILURE",
      "count": 246
    },
    {
      "term": "PULMONARY TUBERCULOSIS",
      "count": 244
    },
    {
      "term": "RASH",
      "count": 238
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 232
    },
    {
      "term": "DIARRHOEA",
      "count": 220
    },
    {
      "term": "DYSPNOEA",
      "count": 220
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 214
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 197
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 195
    },
    {
      "term": "ARTHRALGIA",
      "count": 193
    },
    {
      "term": "DISSEMINATED TUBERCULOSIS",
      "count": 191
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 180
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME ASSOCIATED TUBERCULOSIS",
      "count": 173
    },
    {
      "term": "ASTHENIA",
      "count": 172
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 171
    },
    {
      "term": "DEATH",
      "count": 170
    },
    {
      "term": "PRURITUS",
      "count": 167
    },
    {
      "term": "DECREASED APPETITE",
      "count": 163
    },
    {
      "term": "HEADACHE",
      "count": 160
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 160
    },
    {
      "term": "PNEUMONIA",
      "count": 157
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 149
    },
    {
      "term": "PANCYTOPENIA",
      "count": 148
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 147
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 146
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 143
    },
    {
      "term": "DIZZINESS",
      "count": 141
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 133
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 130
    },
    {
      "term": "FATIGUE",
      "count": 128
    },
    {
      "term": "HYPOTENSION",
      "count": 127
    },
    {
      "term": "SEPSIS",
      "count": 127
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 127
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 122
    },
    {
      "term": "EOSINOPHILIA",
      "count": 119
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 118
    },
    {
      "term": "COUGH",
      "count": 116
    },
    {
      "term": "NEUTROPENIA",
      "count": 116
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 115
    },
    {
      "term": "MALAISE",
      "count": 115
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 114
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 114
    },
    {
      "term": "IMMUNE RECONSTITUTION SYNDROME",
      "count": 113
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 111
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 107
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 101
    },
    {
      "term": "DRUG LEVEL DECREASED",
      "count": 100
    },
    {
      "term": "HEPATIC ENCEPHALOPATHY",
      "count": 99
    },
    {
      "term": "LEUKOPENIA",
      "count": 99
    },
    {
      "term": "SEIZURE",
      "count": 99
    },
    {
      "term": "TUBERCULOMA OF CENTRAL NERVOUS SYSTEM",
      "count": 97
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 96
    },
    {
      "term": "LIVER FUNCTION TEST ABNORMAL",
      "count": 95
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 94
    },
    {
      "term": "CHEST PAIN",
      "count": 93
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 93
    },
    {
      "term": "MENINGITIS TUBERCULOUS",
      "count": 93
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 89
    },
    {
      "term": "RENAL FAILURE",
      "count": 89
    },
    {
      "term": "TREATMENT NONCOMPLIANCE",
      "count": 89
    },
    {
      "term": "ERYTHEMA",
      "count": 88
    },
    {
      "term": "HEPATITIS TOXIC",
      "count": 84
    },
    {
      "term": "LIVER INJURY",
      "count": 84
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 83
    },
    {
      "term": "ASCITES",
      "count": 80
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 80
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 80
    },
    {
      "term": "MYALGIA",
      "count": 79
    },
    {
      "term": "PSYCHOTIC DISORDER",
      "count": 77
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 76
    },
    {
      "term": "SOMNOLENCE",
      "count": 76
    },
    {
      "term": "HYDROCEPHALUS",
      "count": 74
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 72
    },
    {
      "term": "MULTIPLE-DRUG RESISTANCE",
      "count": 71
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 70
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 70
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 69
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 69
    },
    {
      "term": "HYPERTRANSAMINASAEMIA",
      "count": 67
    },
    {
      "term": "INTERNATIONAL NORMALISED RATIO INCREASED",
      "count": 67
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 67
    },
    {
      "term": "HYPERURICAEMIA",
      "count": 66
    }
  ]
}