{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEPENDENCE",
      "count": 3528
    },
    {
      "term": "INTENTIONAL OVERDOSE",
      "count": 2031
    },
    {
      "term": "INTENTIONAL SELF-INJURY",
      "count": 1863
    },
    {
      "term": "OVERDOSE",
      "count": 807
    },
    {
      "term": "FATIGUE",
      "count": 749
    },
    {
      "term": "NAUSEA",
      "count": 664
    },
    {
      "term": "BACK PAIN",
      "count": 569
    },
    {
      "term": "PAIN",
      "count": 494
    },
    {
      "term": "VOMITING",
      "count": 490
    },
    {
      "term": "TACHYCARDIA",
      "count": 448
    },
    {
      "term": "HEADACHE",
      "count": 404
    },
    {
      "term": "ANXIETY",
      "count": 377
    },
    {
      "term": "DYSPNOEA",
      "count": 364
    },
    {
      "term": "DIARRHOEA",
      "count": 363
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 358
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 346
    },
    {
      "term": "SOMNOLENCE",
      "count": 333
    },
    {
      "term": "DEATH",
      "count": 321
    },
    {
      "term": "PNEUMONIA",
      "count": 305
    },
    {
      "term": "DIZZINESS",
      "count": 302
    },
    {
      "term": "PYREXIA",
      "count": 297
    },
    {
      "term": "OFF LABEL USE",
      "count": 289
    },
    {
      "term": "ARTHRALGIA",
      "count": 284
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 264
    },
    {
      "term": "MALAISE",
      "count": 254
    },
    {
      "term": "BACK INJURY",
      "count": 247
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 240
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 233
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 219
    },
    {
      "term": "AKATHISIA",
      "count": 216
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 190
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 188
    },
    {
      "term": "FALL",
      "count": 186
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 180
    },
    {
      "term": "ASTHENIA",
      "count": 179
    },
    {
      "term": "ANAEMIA",
      "count": 177
    },
    {
      "term": "DEPRESSION",
      "count": 174
    },
    {
      "term": "CONSTIPATION",
      "count": 169
    },
    {
      "term": "HALLUCINATION",
      "count": 168
    },
    {
      "term": "CHEST PAIN",
      "count": 167
    },
    {
      "term": "DECREASED APPETITE",
      "count": 166
    },
    {
      "term": "MIGRAINE",
      "count": 163
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 162
    },
    {
      "term": "AGITATION",
      "count": 161
    },
    {
      "term": "COUGH",
      "count": 160
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 158
    },
    {
      "term": "PRURITUS",
      "count": 158
    },
    {
      "term": "MYDRIASIS",
      "count": 155
    },
    {
      "term": "TREMOR",
      "count": 153
    },
    {
      "term": "ILLNESS",
      "count": 150
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 150
    },
    {
      "term": "RASH",
      "count": 149
    },
    {
      "term": "COVID-19",
      "count": 148
    },
    {
      "term": "INSOMNIA",
      "count": 148
    },
    {
      "term": "HYPOTENSION",
      "count": 147
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 146
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 143
    },
    {
      "term": "SINUSITIS",
      "count": 136
    },
    {
      "term": "SUICIDAL IDEATION",
      "count": 134
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 133
    },
    {
      "term": "INFECTION",
      "count": 131
    },
    {
      "term": "DEHYDRATION",
      "count": 128
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 128
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 127
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 126
    },
    {
      "term": "HYPERTENSION",
      "count": 123
    },
    {
      "term": "SEIZURE",
      "count": 123
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 120
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 116
    },
    {
      "term": "PALPITATIONS",
      "count": 109
    },
    {
      "term": "SINUS TACHYCARDIA",
      "count": 109
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 106
    },
    {
      "term": "ROAD TRAFFIC ACCIDENT",
      "count": 105
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 102
    },
    {
      "term": "NECK PAIN",
      "count": 102
    },
    {
      "term": "SEPSIS",
      "count": 100
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 99
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 95
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 95
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 94
    },
    {
      "term": "DRUG ABUSE",
      "count": 93
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 93
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 93
    },
    {
      "term": "LETHARGY",
      "count": 93
    },
    {
      "term": "ASTHMA",
      "count": 92
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 90
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 90
    },
    {
      "term": "RENAL FAILURE",
      "count": 90
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 89
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 89
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 84
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 84
    },
    {
      "term": "SPINAL OPERATION",
      "count": 83
    },
    {
      "term": "CARDIAC ARREST",
      "count": 82
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 82
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 82
    },
    {
      "term": "INFLUENZA",
      "count": 82
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 82
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 82
    },
    {
      "term": "DRUG INTERACTION",
      "count": 81
    }
  ]
}