{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 15861
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 13671
    },
    {
      "term": "PYREXIA",
      "count": 8966
    },
    {
      "term": "DYSPNOEA",
      "count": 7448
    },
    {
      "term": "PNEUMONIA",
      "count": 7345
    },
    {
      "term": "DIARRHOEA",
      "count": 7174
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 6382
    },
    {
      "term": "NAUSEA",
      "count": 5958
    },
    {
      "term": "FATIGUE",
      "count": 5558
    },
    {
      "term": "VOMITING",
      "count": 5498
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 5167
    },
    {
      "term": "HEADACHE",
      "count": 5109
    },
    {
      "term": "SEPSIS",
      "count": 4797
    },
    {
      "term": "RASH",
      "count": 4710
    },
    {
      "term": "ARTHRALGIA",
      "count": 4502
    },
    {
      "term": "MALAISE",
      "count": 4495
    },
    {
      "term": "PAIN",
      "count": 4260
    },
    {
      "term": "ANAEMIA",
      "count": 4235
    },
    {
      "term": "DEATH",
      "count": 3938
    },
    {
      "term": "DIZZINESS",
      "count": 3633
    },
    {
      "term": "NEUTROPENIA",
      "count": 3614
    },
    {
      "term": "INFECTION",
      "count": 3602
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 3533
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 3492
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 3458
    },
    {
      "term": "DRUG INTERACTION",
      "count": 3441
    },
    {
      "term": "HYPERTENSION",
      "count": 3299
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 3285
    },
    {
      "term": "ASTHENIA",
      "count": 3273
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 3266
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 3184
    },
    {
      "term": "COUGH",
      "count": 3183
    },
    {
      "term": "COVID-19",
      "count": 3128
    },
    {
      "term": "DECREASED APPETITE",
      "count": 3097
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 3023
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 2969
    },
    {
      "term": "PRURITUS",
      "count": 2920
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 2861
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 2850
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 2724
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 2657
    },
    {
      "term": "PANCYTOPENIA",
      "count": 2580
    },
    {
      "term": "FALL",
      "count": 2577
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 2551
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 2536
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 2530
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 2394
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 2389
    },
    {
      "term": "CHEST PAIN",
      "count": 2353
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 2294
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 2264
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 2239
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 2215
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 2174
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 2150
    },
    {
      "term": "LEUKOPENIA",
      "count": 2147
    },
    {
      "term": "ERYTHEMA",
      "count": 2138
    },
    {
      "term": "RENAL FAILURE",
      "count": 2114
    },
    {
      "term": "JOINT SWELLING",
      "count": 2111
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 2106
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 2099
    },
    {
      "term": "ALOPECIA",
      "count": 2023
    },
    {
      "term": "INSOMNIA",
      "count": 2012
    },
    {
      "term": "BACK PAIN",
      "count": 2002
    },
    {
      "term": "ASTHMA",
      "count": 1999
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 1990
    },
    {
      "term": "HYPOTENSION",
      "count": 1984
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 1955
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 1932
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 1908
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 1868
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 1816
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 1810
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 1795
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 1785
    },
    {
      "term": "URTICARIA",
      "count": 1776
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 1774
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 1746
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 1745
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 1732
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 1725
    },
    {
      "term": "ANXIETY",
      "count": 1720
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 1708
    },
    {
      "term": "DEPRESSION",
      "count": 1690
    },
    {
      "term": "CONSTIPATION",
      "count": 1678
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 1661
    },
    {
      "term": "HERPES ZOSTER",
      "count": 1655
    },
    {
      "term": "LIVER DISORDER",
      "count": 1628
    },
    {
      "term": "WHEEZING",
      "count": 1614
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 1611
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 1609
    },
    {
      "term": "TACHYCARDIA",
      "count": 1604
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 1596
    },
    {
      "term": "OEDEMA",
      "count": 1585
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 1577
    },
    {
      "term": "INFLAMMATION",
      "count": 1563
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 1563
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 1560
    },
    {
      "term": "STOMATITIS",
      "count": 1556
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 1543
    }
  ]
}