{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "RASH",
      "count": 172
    },
    {
      "term": "OFF LABEL USE",
      "count": 161
    },
    {
      "term": "INFECTION",
      "count": 159
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 155
    },
    {
      "term": "SLEEP DISORDER",
      "count": 151
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 128
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 127
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 117
    },
    {
      "term": "DIARRHOEA",
      "count": 116
    },
    {
      "term": "PYREXIA",
      "count": 106
    },
    {
      "term": "PNEUMONIA",
      "count": 96
    },
    {
      "term": "NAUSEA",
      "count": 95
    },
    {
      "term": "PAIN",
      "count": 86
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 85
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 85
    },
    {
      "term": "FATIGUE",
      "count": 84
    },
    {
      "term": "VOMITING",
      "count": 81
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 78
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 76
    },
    {
      "term": "ANAEMIA",
      "count": 72
    },
    {
      "term": "DYSPNOEA",
      "count": 71
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 69
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 68
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 66
    },
    {
      "term": "HYPOTENSION",
      "count": 66
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 63
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 62
    },
    {
      "term": "SEPSIS",
      "count": 61
    },
    {
      "term": "CONSTIPATION",
      "count": 55
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 52
    },
    {
      "term": "HEADACHE",
      "count": 52
    },
    {
      "term": "DEATH",
      "count": 50
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 50
    },
    {
      "term": "ASTHENIA",
      "count": 49
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 48
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 47
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 46
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 45
    },
    {
      "term": "HYPERTENSION",
      "count": 43
    },
    {
      "term": "HYPOPHOSPHATAEMIA",
      "count": 43
    },
    {
      "term": "DEHYDRATION",
      "count": 41
    },
    {
      "term": "COUGH",
      "count": 40
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 40
    },
    {
      "term": "FALL",
      "count": 40
    },
    {
      "term": "NEUTROPENIA",
      "count": 40
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 39
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 38
    },
    {
      "term": "CARDIAC ARREST",
      "count": 37
    },
    {
      "term": "DECREASED APPETITE",
      "count": 36
    },
    {
      "term": "MALAISE",
      "count": 36
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 35
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 32
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 31
    },
    {
      "term": "SKIN LESION",
      "count": 31
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 30
    },
    {
      "term": "HYPOXIA",
      "count": 30
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 30
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 30
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 30
    },
    {
      "term": "ANXIETY",
      "count": 29
    },
    {
      "term": "JOINT STIFFNESS",
      "count": 29
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 29
    },
    {
      "term": "SYNOVITIS",
      "count": 28
    },
    {
      "term": "ARTHRALGIA",
      "count": 27
    },
    {
      "term": "HERPES ZOSTER",
      "count": 27
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 26
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 26
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 26
    },
    {
      "term": "DIZZINESS",
      "count": 25
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 25
    },
    {
      "term": "RENAL FAILURE",
      "count": 25
    },
    {
      "term": "TACHYCARDIA",
      "count": 25
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 24
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 24
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 23
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 23
    },
    {
      "term": "TORSADE DE POINTES",
      "count": 23
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 22
    },
    {
      "term": "SYNCOPE",
      "count": 22
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 21
    },
    {
      "term": "METHAEMOGLOBINAEMIA",
      "count": 21
    },
    {
      "term": "NEUROTOXICITY",
      "count": 21
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 21
    },
    {
      "term": "COLITIS",
      "count": 20
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 20
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 19
    },
    {
      "term": "ARRHYTHMIA",
      "count": 19
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 19
    },
    {
      "term": "BACK PAIN",
      "count": 19
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 19
    },
    {
      "term": "DRUG INTERACTION",
      "count": 19
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 19
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 19
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 19
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 19
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 18
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 18
    },
    {
      "term": "BLOOD PHOSPHORUS DECREASED",
      "count": 18
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 18
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 18
    }
  ]
}