{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1291
    },
    {
      "term": "OFF LABEL USE",
      "count": 1161
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 879
    },
    {
      "term": "DRUG INTERACTION",
      "count": 753
    },
    {
      "term": "PYREXIA",
      "count": 642
    },
    {
      "term": "NEUTROPENIA",
      "count": 636
    },
    {
      "term": "DEATH",
      "count": 580
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 534
    },
    {
      "term": "PNEUMONIA",
      "count": 480
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 403
    },
    {
      "term": "DIARRHOEA",
      "count": 370
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 365
    },
    {
      "term": "NAUSEA",
      "count": 339
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 337
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 322
    },
    {
      "term": "SEPSIS",
      "count": 304
    },
    {
      "term": "PANCYTOPENIA",
      "count": 302
    },
    {
      "term": "FATIGUE",
      "count": 295
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 261
    },
    {
      "term": "ANAEMIA",
      "count": 239
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 235
    },
    {
      "term": "DYSPNOEA",
      "count": 223
    },
    {
      "term": "INFECTION",
      "count": 220
    },
    {
      "term": "VOMITING",
      "count": 218
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 217
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 217
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 213
    },
    {
      "term": "ASTHENIA",
      "count": 212
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 205
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 203
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 199
    },
    {
      "term": "RENAL FAILURE",
      "count": 188
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 187
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 186
    },
    {
      "term": "HEADACHE",
      "count": 185
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 176
    },
    {
      "term": "HYPOTENSION",
      "count": 172
    },
    {
      "term": "MUCORMYCOSIS",
      "count": 169
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 167
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 155
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 152
    },
    {
      "term": "PNEUMONIA FUNGAL",
      "count": 150
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 150
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 148
    },
    {
      "term": "RASH",
      "count": 139
    },
    {
      "term": "DECREASED APPETITE",
      "count": 137
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 135
    },
    {
      "term": "COVID-19",
      "count": 133
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA RECURRENT",
      "count": 131
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 131
    },
    {
      "term": "BACTERAEMIA",
      "count": 130
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 130
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 129
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 128
    },
    {
      "term": "COUGH",
      "count": 125
    },
    {
      "term": "CYTOPENIA",
      "count": 124
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 123
    },
    {
      "term": "CONSTIPATION",
      "count": 122
    },
    {
      "term": "HYPOXIA",
      "count": 118
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 117
    },
    {
      "term": "DIZZINESS",
      "count": 115
    },
    {
      "term": "HYPERTENSION",
      "count": 115
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 115
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 114
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 112
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 110
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 110
    },
    {
      "term": "PAIN",
      "count": 110
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 110
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 109
    },
    {
      "term": "PSEUDOMONAS INFECTION",
      "count": 109
    },
    {
      "term": "DEVICE RELATED INFECTION",
      "count": 106
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 104
    },
    {
      "term": "CARDIAC ARREST",
      "count": 102
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 102
    },
    {
      "term": "FUSARIUM INFECTION",
      "count": 100
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 99
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 97
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 97
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 96
    },
    {
      "term": "CHOLESTASIS",
      "count": 95
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 94
    },
    {
      "term": "TACHYCARDIA",
      "count": 94
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 93
    },
    {
      "term": "FALL",
      "count": 92
    },
    {
      "term": "NEUROTOXICITY",
      "count": 90
    },
    {
      "term": "HAEMORRHAGE",
      "count": 89
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 89
    },
    {
      "term": "CELLULITIS",
      "count": 88
    },
    {
      "term": "HYPERBILIRUBINAEMIA",
      "count": 88
    },
    {
      "term": "MYOSITIS",
      "count": 88
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 87
    },
    {
      "term": "CHRONIC GRAFT VERSUS HOST DISEASE",
      "count": 86
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 85
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 85
    },
    {
      "term": "SYSTEMIC CANDIDA",
      "count": 85
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 85
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 84
    },
    {
      "term": "MALAISE",
      "count": 84
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 84
    }
  ]
}