{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 2696
    },
    {
      "term": "SEIZURE",
      "count": 1713
    },
    {
      "term": "OFF LABEL USE",
      "count": 1524
    },
    {
      "term": "CONVULSION",
      "count": 882
    },
    {
      "term": "DRUG INTERACTION",
      "count": 838
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 707
    },
    {
      "term": "SOMNOLENCE",
      "count": 634
    },
    {
      "term": "STATUS EPILEPTICUS",
      "count": 612
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 582
    },
    {
      "term": "PYREXIA",
      "count": 581
    },
    {
      "term": "FALL",
      "count": 569
    },
    {
      "term": "EPILEPSY",
      "count": 559
    },
    {
      "term": "HYPOTENSION",
      "count": 485
    },
    {
      "term": "MULTIPLE-DRUG RESISTANCE",
      "count": 476
    },
    {
      "term": "VOMITING",
      "count": 466
    },
    {
      "term": "PNEUMONIA",
      "count": 455
    },
    {
      "term": "FATIGUE",
      "count": 442
    },
    {
      "term": "NAUSEA",
      "count": 429
    },
    {
      "term": "HEADACHE",
      "count": 428
    },
    {
      "term": "OVERDOSE",
      "count": 427
    },
    {
      "term": "DIARRHOEA",
      "count": 412
    },
    {
      "term": "DIZZINESS",
      "count": 404
    },
    {
      "term": "DYSPNOEA",
      "count": 402
    },
    {
      "term": "DEATH",
      "count": 399
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 397
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 375
    },
    {
      "term": "PAIN",
      "count": 361
    },
    {
      "term": "RASH",
      "count": 352
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 334
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 332
    },
    {
      "term": "ASTHENIA",
      "count": 323
    },
    {
      "term": "COMA",
      "count": 316
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 298
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 297
    },
    {
      "term": "DRUG ABUSE",
      "count": 292
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 292
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 279
    },
    {
      "term": "MALAISE",
      "count": 277
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 270
    },
    {
      "term": "CARDIAC ARREST",
      "count": 262
    },
    {
      "term": "COGNITIVE DISORDER",
      "count": 262
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 260
    },
    {
      "term": "INSOMNIA",
      "count": 259
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 255
    },
    {
      "term": "CONSTIPATION",
      "count": 252
    },
    {
      "term": "GENERALISED TONIC-CLONIC SEIZURE",
      "count": 251
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 250
    },
    {
      "term": "SEDATION",
      "count": 242
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 237
    },
    {
      "term": "TREMOR",
      "count": 237
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 235
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 224
    },
    {
      "term": "TACHYCARDIA",
      "count": 224
    },
    {
      "term": "DECREASED APPETITE",
      "count": 223
    },
    {
      "term": "BALANCE DISORDER",
      "count": 216
    },
    {
      "term": "DEPRESSION",
      "count": 215
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 215
    },
    {
      "term": "ANXIETY",
      "count": 211
    },
    {
      "term": "COUGH",
      "count": 204
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 204
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 201
    },
    {
      "term": "SEPSIS",
      "count": 199
    },
    {
      "term": "PNEUMONIA ASPIRATION",
      "count": 198
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 195
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 195
    },
    {
      "term": "IRRITABILITY",
      "count": 194
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 191
    },
    {
      "term": "PRURITUS",
      "count": 189
    },
    {
      "term": "AGITATION",
      "count": 188
    },
    {
      "term": "ARTHRALGIA",
      "count": 186
    },
    {
      "term": "ANAEMIA",
      "count": 183
    },
    {
      "term": "HYPERTENSION",
      "count": 183
    },
    {
      "term": "DRUG DOSE OMISSION",
      "count": 180
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 180
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 175
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 173
    },
    {
      "term": "PARTIAL SEIZURES",
      "count": 171
    },
    {
      "term": "AGGRESSION",
      "count": 168
    },
    {
      "term": "ATAXIA",
      "count": 168
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 166
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 161
    },
    {
      "term": "LETHARGY",
      "count": 157
    },
    {
      "term": "RENAL FAILURE",
      "count": 156
    },
    {
      "term": "NEUTROPENIA",
      "count": 155
    },
    {
      "term": "GRAND MAL CONVULSION",
      "count": 154
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 153
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 152
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 151
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 151
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 149
    },
    {
      "term": "BRADYCARDIA",
      "count": 149
    },
    {
      "term": "BACK PAIN",
      "count": 148
    },
    {
      "term": "CHEST PAIN",
      "count": 148
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 148
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 147
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 146
    },
    {
      "term": "INTENTIONAL OVERDOSE",
      "count": 146
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 146
    },
    {
      "term": "INFECTION",
      "count": 143
    },
    {
      "term": "PETIT MAL EPILEPSY",
      "count": 142
    }
  ]
}