{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DIARRHOEA",
      "count": 2017
    },
    {
      "term": "OFF LABEL USE",
      "count": 1613
    },
    {
      "term": "NAUSEA",
      "count": 1121
    },
    {
      "term": "FATIGUE",
      "count": 1106
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 825
    },
    {
      "term": "VOMITING",
      "count": 780
    },
    {
      "term": "NEUTROPENIA",
      "count": 732
    },
    {
      "term": "ALOPECIA",
      "count": 703
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 696
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 685
    },
    {
      "term": "DYSPNOEA",
      "count": 628
    },
    {
      "term": "ANAEMIA",
      "count": 601
    },
    {
      "term": "PYREXIA",
      "count": 586
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 490
    },
    {
      "term": "EJECTION FRACTION DECREASED",
      "count": 434
    },
    {
      "term": "HEADACHE",
      "count": 431
    },
    {
      "term": "DECREASED APPETITE",
      "count": 422
    },
    {
      "term": "ASTHENIA",
      "count": 406
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 404
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 386
    },
    {
      "term": "METASTASES TO CENTRAL NERVOUS SYSTEM",
      "count": 383
    },
    {
      "term": "DEATH",
      "count": 355
    },
    {
      "term": "PNEUMONIA",
      "count": 348
    },
    {
      "term": "CONSTIPATION",
      "count": 345
    },
    {
      "term": "RASH",
      "count": 344
    },
    {
      "term": "POLYNEUROPATHY",
      "count": 342
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 338
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 336
    },
    {
      "term": "BACK PAIN",
      "count": 311
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 309
    },
    {
      "term": "STOMATITIS",
      "count": 299
    },
    {
      "term": "COUGH",
      "count": 294
    },
    {
      "term": "PRURITUS",
      "count": 288
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 271
    },
    {
      "term": "ARTHRALGIA",
      "count": 268
    },
    {
      "term": "DIZZINESS",
      "count": 267
    },
    {
      "term": "PAIN",
      "count": 255
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 254
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 252
    },
    {
      "term": "LEUKOPENIA",
      "count": 245
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 240
    },
    {
      "term": "CELLULITIS",
      "count": 227
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 223
    },
    {
      "term": "DEHYDRATION",
      "count": 221
    },
    {
      "term": "EPISTAXIS",
      "count": 219
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 218
    },
    {
      "term": "MALAISE",
      "count": 216
    },
    {
      "term": "SEPSIS",
      "count": 216
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 213
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 212
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 209
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 205
    },
    {
      "term": "MYALGIA",
      "count": 204
    },
    {
      "term": "PARAESTHESIA",
      "count": 199
    },
    {
      "term": "DYSPEPSIA",
      "count": 197
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 195
    },
    {
      "term": "LEFT VENTRICULAR DYSFUNCTION",
      "count": 194
    },
    {
      "term": "CARDIOTOXICITY",
      "count": 186
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 184
    },
    {
      "term": "CHILLS",
      "count": 183
    },
    {
      "term": "PNEUMONITIS",
      "count": 180
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 177
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 176
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 175
    },
    {
      "term": "SEIZURE",
      "count": 174
    },
    {
      "term": "COVID-19",
      "count": 173
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 171
    },
    {
      "term": "DYSGEUSIA",
      "count": 170
    },
    {
      "term": "INSOMNIA",
      "count": 164
    },
    {
      "term": "HYPERTENSION",
      "count": 163
    },
    {
      "term": "METASTASES TO BONE",
      "count": 163
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 157
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 156
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 153
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 149
    },
    {
      "term": "VASCULAR DEVICE INFECTION",
      "count": 149
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 147
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 145
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 145
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 144
    },
    {
      "term": "CHEST PAIN",
      "count": 143
    },
    {
      "term": "BREAST CANCER",
      "count": 141
    },
    {
      "term": "OVERDOSE",
      "count": 139
    },
    {
      "term": "HYPOTENSION",
      "count": 138
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 137
    },
    {
      "term": "PERIPHERAL SENSORY NEUROPATHY",
      "count": 134
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 129
    },
    {
      "term": "PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME",
      "count": 128
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 128
    },
    {
      "term": "ERYTHEMA",
      "count": 127
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 126
    },
    {
      "term": "COLITIS",
      "count": 125
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 125
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 123
    },
    {
      "term": "PANCYTOPENIA",
      "count": 123
    },
    {
      "term": "INFECTION",
      "count": 120
    },
    {
      "term": "TREMOR",
      "count": 119
    },
    {
      "term": "HAIR COLOUR CHANGES",
      "count": 118
    },
    {
      "term": "HAIR TEXTURE ABNORMAL",
      "count": 118
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 118
    }
  ]
}