{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 834
    },
    {
      "term": "OFF LABEL USE",
      "count": 435
    },
    {
      "term": "SEIZURE",
      "count": 417
    },
    {
      "term": "MULTIPLE-DRUG RESISTANCE",
      "count": 288
    },
    {
      "term": "STATUS EPILEPTICUS",
      "count": 240
    },
    {
      "term": "DRUG INTERACTION",
      "count": 213
    },
    {
      "term": "EPILEPSY",
      "count": 175
    },
    {
      "term": "SOMNOLENCE",
      "count": 174
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 164
    },
    {
      "term": "AGGRESSION",
      "count": 150
    },
    {
      "term": "DIZZINESS",
      "count": 135
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 98
    },
    {
      "term": "FATIGUE",
      "count": 95
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 94
    },
    {
      "term": "GENERALISED TONIC-CLONIC SEIZURE",
      "count": 92
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 92
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 87
    },
    {
      "term": "COGNITIVE DISORDER",
      "count": 85
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 82
    },
    {
      "term": "IRRITABILITY",
      "count": 80
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 76
    },
    {
      "term": "OVERDOSE",
      "count": 74
    },
    {
      "term": "FALL",
      "count": 73
    },
    {
      "term": "DEPRESSION",
      "count": 70
    },
    {
      "term": "HEADACHE",
      "count": 70
    },
    {
      "term": "NAUSEA",
      "count": 65
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 64
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 64
    },
    {
      "term": "PYREXIA",
      "count": 60
    },
    {
      "term": "PNEUMONIA",
      "count": 58
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 56
    },
    {
      "term": "INTENTIONAL OVERDOSE",
      "count": 55
    },
    {
      "term": "PARTIAL SEIZURES",
      "count": 54
    },
    {
      "term": "TREMOR",
      "count": 54
    },
    {
      "term": "AGITATION",
      "count": 53
    },
    {
      "term": "PNEUMONIA ASPIRATION",
      "count": 53
    },
    {
      "term": "RASH",
      "count": 52
    },
    {
      "term": "HALLUCINATION",
      "count": 51
    },
    {
      "term": "SUICIDAL IDEATION",
      "count": 50
    },
    {
      "term": "VOMITING",
      "count": 50
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 49
    },
    {
      "term": "PETIT MAL EPILEPSY",
      "count": 48
    },
    {
      "term": "ANXIETY",
      "count": 47
    },
    {
      "term": "ATAXIA",
      "count": 47
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 46
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 45
    },
    {
      "term": "PSYCHOTIC DISORDER",
      "count": 44
    },
    {
      "term": "HYPERAMMONAEMIA",
      "count": 42
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 41
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 40
    },
    {
      "term": "DYSARTHRIA",
      "count": 40
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 40
    },
    {
      "term": "ASTHENIA",
      "count": 37
    },
    {
      "term": "DISTURBANCE IN ATTENTION",
      "count": 37
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 37
    },
    {
      "term": "BEHAVIOUR DISORDER",
      "count": 36
    },
    {
      "term": "DECREASED APPETITE",
      "count": 36
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 36
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 35
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 34
    },
    {
      "term": "MYOCLONIC EPILEPSY",
      "count": 33
    },
    {
      "term": "ABNORMAL BEHAVIOUR",
      "count": 32
    },
    {
      "term": "ALTERED STATE OF CONSCIOUSNESS",
      "count": 32
    },
    {
      "term": "BALANCE DISORDER",
      "count": 32
    },
    {
      "term": "DEPRESSED MOOD",
      "count": 32
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 32
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 32
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 31
    },
    {
      "term": "TREATMENT NONCOMPLIANCE",
      "count": 31
    },
    {
      "term": "DIARRHOEA",
      "count": 30
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 30
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 30
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 29
    },
    {
      "term": "MOOD ALTERED",
      "count": 29
    },
    {
      "term": "NEW ONSET REFRACTORY STATUS EPILEPTICUS",
      "count": 29
    },
    {
      "term": "TONIC CONVULSION",
      "count": 29
    },
    {
      "term": "ANTICONVULSANT DRUG LEVEL INCREASED",
      "count": 28
    },
    {
      "term": "BRADYCARDIA",
      "count": 28
    },
    {
      "term": "HYPOTENSION",
      "count": 28
    },
    {
      "term": "SPEECH DISORDER",
      "count": 28
    },
    {
      "term": "MENTAL DISORDER",
      "count": 27
    },
    {
      "term": "ANGER",
      "count": 26
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 26
    },
    {
      "term": "TACHYCARDIA",
      "count": 26
    },
    {
      "term": "CARDIAC ARREST",
      "count": 25
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 25
    },
    {
      "term": "LIVER FUNCTION TEST ABNORMAL",
      "count": 25
    },
    {
      "term": "MYOCLONUS",
      "count": 25
    },
    {
      "term": "POSTICTAL PARALYSIS",
      "count": 25
    },
    {
      "term": "ABORTION SPONTANEOUS",
      "count": 24
    },
    {
      "term": "ADVERSE DRUG REACTION",
      "count": 24
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 24
    },
    {
      "term": "HALLUCINATION, AUDITORY",
      "count": 24
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 24
    },
    {
      "term": "INSOMNIA",
      "count": 24
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 24
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 24
    },
    {
      "term": "REBOUND EFFECT",
      "count": 24
    },
    {
      "term": "FOCAL DYSCOGNITIVE SEIZURES",
      "count": 23
    },
    {
      "term": "INFECTION",
      "count": 23
    }
  ]
}