{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 396
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 380
    },
    {
      "term": "ANAEMIA",
      "count": 195
    },
    {
      "term": "DIARRHOEA",
      "count": 182
    },
    {
      "term": "NAUSEA",
      "count": 175
    },
    {
      "term": "DEATH",
      "count": 151
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 143
    },
    {
      "term": "RASH",
      "count": 141
    },
    {
      "term": "NEUTROPENIA",
      "count": 140
    },
    {
      "term": "PYREXIA",
      "count": 136
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 134
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 131
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 128
    },
    {
      "term": "PNEUMONIA",
      "count": 127
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 126
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 120
    },
    {
      "term": "PANCYTOPENIA",
      "count": 119
    },
    {
      "term": "VOMITING",
      "count": 119
    },
    {
      "term": "FATIGUE",
      "count": 114
    },
    {
      "term": "OFF LABEL USE",
      "count": 113
    },
    {
      "term": "ASTHENIA",
      "count": 110
    },
    {
      "term": "DECREASED APPETITE",
      "count": 104
    },
    {
      "term": "DYSPNOEA",
      "count": 103
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 97
    },
    {
      "term": "PNEUMONITIS",
      "count": 84
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 83
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 76
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 71
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 70
    },
    {
      "term": "DEHYDRATION",
      "count": 64
    },
    {
      "term": "LEUKOPENIA",
      "count": 60
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 60
    },
    {
      "term": "PRURITUS",
      "count": 59
    },
    {
      "term": "SEPSIS",
      "count": 59
    },
    {
      "term": "IMMUNE-MEDIATED HEPATIC DISORDER",
      "count": 58
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 53
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 53
    },
    {
      "term": "CONSTIPATION",
      "count": 52
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 52
    },
    {
      "term": "MALAISE",
      "count": 51
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 50
    },
    {
      "term": "RENAL FAILURE",
      "count": 47
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 45
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 43
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 42
    },
    {
      "term": "DIZZINESS",
      "count": 41
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 40
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 40
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 39
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 38
    },
    {
      "term": "IMMUNE-MEDIATED ENTEROCOLITIS",
      "count": 38
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 37
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 37
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 35
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 35
    },
    {
      "term": "COLITIS",
      "count": 34
    },
    {
      "term": "HAEMOPTYSIS",
      "count": 34
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 34
    },
    {
      "term": "INFECTION",
      "count": 34
    },
    {
      "term": "HYPOTHYROIDISM",
      "count": 33
    },
    {
      "term": "LIVER DISORDER",
      "count": 32
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 31
    },
    {
      "term": "COUGH",
      "count": 31
    },
    {
      "term": "HYPERTENSION",
      "count": 31
    },
    {
      "term": "HYPOTENSION",
      "count": 31
    },
    {
      "term": "EPISTAXIS",
      "count": 30
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 30
    },
    {
      "term": "HEPATITIS",
      "count": 29
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 29
    },
    {
      "term": "IMMUNE-MEDIATED LUNG DISEASE",
      "count": 28
    },
    {
      "term": "ADRENAL INSUFFICIENCY",
      "count": 27
    },
    {
      "term": "CHEST PAIN",
      "count": 27
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 27
    },
    {
      "term": "PAIN",
      "count": 27
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 27
    },
    {
      "term": "ARTHRALGIA",
      "count": 26
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 26
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 26
    },
    {
      "term": "HEADACHE",
      "count": 26
    },
    {
      "term": "LUNG DISORDER",
      "count": 26
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 26
    },
    {
      "term": "PULMONARY TOXICITY",
      "count": 26
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 26
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 25
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 25
    },
    {
      "term": "MYOCARDITIS",
      "count": 25
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 25
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 25
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 24
    },
    {
      "term": "SYNCOPE",
      "count": 24
    },
    {
      "term": "ADVERSE EVENT",
      "count": 23
    },
    {
      "term": "DYSPHAGIA",
      "count": 23
    },
    {
      "term": "IMMUNE-MEDIATED ADVERSE REACTION",
      "count": 23
    },
    {
      "term": "PNEUMONIA BACTERIAL",
      "count": 23
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 23
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 23
    },
    {
      "term": "DRUG ERUPTION",
      "count": 22
    },
    {
      "term": "DRUG INTERACTION",
      "count": 22
    },
    {
      "term": "ERYTHEMA",
      "count": 22
    },
    {
      "term": "LIVER INJURY",
      "count": 22
    }
  ]
}