{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 19
    },
    {
      "term": "DIARRHOEA",
      "count": 16
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 16
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 12
    },
    {
      "term": "RASH",
      "count": 10
    },
    {
      "term": "DYSPNOEA",
      "count": 9
    },
    {
      "term": "ARTHRALGIA",
      "count": 8
    },
    {
      "term": "ASCITES",
      "count": 8
    },
    {
      "term": "OFF LABEL USE",
      "count": 8
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 8
    },
    {
      "term": "CYSTITIS",
      "count": 7
    },
    {
      "term": "DESMOPLASTIC SMALL ROUND CELL TUMOUR",
      "count": 7
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 7
    },
    {
      "term": "DISSEMINATED INTRAVASCULAR COAGULATION",
      "count": 6
    },
    {
      "term": "HYPOTHYROIDISM",
      "count": 6
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 6
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 5
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 5
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 5
    },
    {
      "term": "METASTASES TO PERITONEUM",
      "count": 5
    },
    {
      "term": "PYREXIA",
      "count": 5
    },
    {
      "term": "VOMITING",
      "count": 5
    },
    {
      "term": "ADRENAL INSUFFICIENCY",
      "count": 4
    },
    {
      "term": "DEATH",
      "count": 4
    },
    {
      "term": "DECREASED APPETITE",
      "count": 4
    },
    {
      "term": "FATIGUE",
      "count": 4
    },
    {
      "term": "NAUSEA",
      "count": 4
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 4
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 4
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 4
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 4
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 3
    },
    {
      "term": "DRUG INTERACTION",
      "count": 3
    },
    {
      "term": "EMERGENCY CARE",
      "count": 3
    },
    {
      "term": "HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS",
      "count": 3
    },
    {
      "term": "MALAISE",
      "count": 3
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 3
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 3
    },
    {
      "term": "PEMPHIGOID",
      "count": 3
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 3
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 3
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 2
    },
    {
      "term": "ANAEMIA",
      "count": 2
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 2
    },
    {
      "term": "CANCER PAIN",
      "count": 2
    },
    {
      "term": "DIPLEGIA",
      "count": 2
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 2
    },
    {
      "term": "ERYTHEMA",
      "count": 2
    },
    {
      "term": "EXPOSED BONE IN JAW",
      "count": 2
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 2
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 2
    },
    {
      "term": "HYPERTENSION",
      "count": 2
    },
    {
      "term": "IMMUNOSUPPRESSION",
      "count": 2
    },
    {
      "term": "LIVER DISORDER",
      "count": 2
    },
    {
      "term": "METASTASES TO BONE",
      "count": 2
    },
    {
      "term": "PAIN",
      "count": 2
    },
    {
      "term": "PNEUMONIA ASPIRATION",
      "count": 2
    },
    {
      "term": "PNEUMONIA BACTERIAL",
      "count": 2
    },
    {
      "term": "POLYMYOSITIS",
      "count": 2
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 2
    },
    {
      "term": "SHOCK",
      "count": 2
    },
    {
      "term": "THERAPY INTERRUPTED",
      "count": 2
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1
    },
    {
      "term": "ADRENOCORTICOTROPIC HORMONE DEFICIENCY",
      "count": 1
    },
    {
      "term": "ALOPECIA",
      "count": 1
    },
    {
      "term": "ANORECTAL DISORDER",
      "count": 1
    },
    {
      "term": "ASTHENIA",
      "count": 1
    },
    {
      "term": "BLADDER CANCER",
      "count": 1
    },
    {
      "term": "BLADDER DISORDER",
      "count": 1
    },
    {
      "term": "BLISTER",
      "count": 1
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 1
    },
    {
      "term": "BLOOD CREATINE INCREASED",
      "count": 1
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 1
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 1
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 1
    },
    {
      "term": "BLOOD PRESSURE MEASUREMENT",
      "count": 1
    },
    {
      "term": "BLOOD TEST ABNORMAL",
      "count": 1
    },
    {
      "term": "BLOOD THYROID STIMULATING HORMONE ABNORMAL",
      "count": 1
    },
    {
      "term": "BONE LESION",
      "count": 1
    },
    {
      "term": "BONE PAIN",
      "count": 1
    },
    {
      "term": "BRONCHITIS",
      "count": 1
    },
    {
      "term": "BRONCHOPNEUMONIA",
      "count": 1
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 1
    },
    {
      "term": "CARDIAC ARREST",
      "count": 1
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 1
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 1
    },
    {
      "term": "CEREBRAL INFARCTION",
      "count": 1
    },
    {
      "term": "CHILLS",
      "count": 1
    },
    {
      "term": "CHOLECYSTITIS",
      "count": 1
    },
    {
      "term": "CHOLELITHIASIS",
      "count": 1
    },
    {
      "term": "COLITIS",
      "count": 1
    },
    {
      "term": "COMA",
      "count": 1
    },
    {
      "term": "CONJUNCTIVITIS",
      "count": 1
    },
    {
      "term": "CONSTIPATION",
      "count": 1
    },
    {
      "term": "CYSTITIS HAEMORRHAGIC",
      "count": 1
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 1
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 1
    },
    {
      "term": "DEHYDRATION",
      "count": 1
    },
    {
      "term": "DERMATITIS ACNEIFORM",
      "count": 1
    },
    {
      "term": "DRUG EFFECT INCOMPLETE",
      "count": 1
    }
  ]
}