{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "NEUTROPENIA",
      "count": 1767
    },
    {
      "term": "DEATH",
      "count": 1117
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 1113
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 1112
    },
    {
      "term": "FATIGUE",
      "count": 908
    },
    {
      "term": "NAUSEA",
      "count": 650
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 650
    },
    {
      "term": "ASTHENIA",
      "count": 633
    },
    {
      "term": "METASTASES TO BONE",
      "count": 605
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 593
    },
    {
      "term": "ANAEMIA",
      "count": 572
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 541
    },
    {
      "term": "DIARRHOEA",
      "count": 504
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 471
    },
    {
      "term": "DYSPNOEA",
      "count": 464
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 453
    },
    {
      "term": "OFF LABEL USE",
      "count": 444
    },
    {
      "term": "PYREXIA",
      "count": 441
    },
    {
      "term": "VOMITING",
      "count": 414
    },
    {
      "term": "LEUKOPENIA",
      "count": 407
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 404
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 391
    },
    {
      "term": "PAIN",
      "count": 367
    },
    {
      "term": "ARTHRALGIA",
      "count": 358
    },
    {
      "term": "BREAST CANCER",
      "count": 351
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 322
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 307
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 303
    },
    {
      "term": "DECREASED APPETITE",
      "count": 281
    },
    {
      "term": "COUGH",
      "count": 255
    },
    {
      "term": "BACK PAIN",
      "count": 247
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 239
    },
    {
      "term": "CONSTIPATION",
      "count": 225
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 223
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 220
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 219
    },
    {
      "term": "PANCYTOPENIA",
      "count": 218
    },
    {
      "term": "ALOPECIA",
      "count": 212
    },
    {
      "term": "RASH",
      "count": 211
    },
    {
      "term": "PNEUMONIA",
      "count": 208
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 204
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 202
    },
    {
      "term": "DIZZINESS",
      "count": 200
    },
    {
      "term": "HEADACHE",
      "count": 198
    },
    {
      "term": "MALAISE",
      "count": 190
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 188
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 185
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 181
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 181
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 180
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 180
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 176
    },
    {
      "term": "COVID-19",
      "count": 171
    },
    {
      "term": "ASCITES",
      "count": 164
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 164
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 161
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 161
    },
    {
      "term": "RED BLOOD CELL COUNT DECREASED",
      "count": 157
    },
    {
      "term": "FALL",
      "count": 142
    },
    {
      "term": "PRURITUS",
      "count": 142
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 137
    },
    {
      "term": "HYPERTENSION",
      "count": 136
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 133
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 133
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 129
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 128
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 128
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 127
    },
    {
      "term": "PNEUMONITIS",
      "count": 124
    },
    {
      "term": "SECOND PRIMARY MALIGNANCY",
      "count": 124
    },
    {
      "term": "STOMATITIS",
      "count": 124
    },
    {
      "term": "HOT FLUSH",
      "count": 119
    },
    {
      "term": "TUMOUR MARKER INCREASED",
      "count": 116
    },
    {
      "term": "HAEMATOCRIT DECREASED",
      "count": 113
    },
    {
      "term": "BONE PAIN",
      "count": 112
    },
    {
      "term": "CARBOHYDRATE ANTIGEN 15-3 INCREASED",
      "count": 110
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 110
    },
    {
      "term": "METASTASES TO CENTRAL NERVOUS SYSTEM",
      "count": 109
    },
    {
      "term": "DRY SKIN",
      "count": 108
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 108
    },
    {
      "term": "DRUG INTERACTION",
      "count": 107
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 107
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 100
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 98
    },
    {
      "term": "DEHYDRATION",
      "count": 97
    },
    {
      "term": "INSOMNIA",
      "count": 97
    },
    {
      "term": "RENAL FAILURE",
      "count": 96
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 95
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 93
    },
    {
      "term": "SEPSIS",
      "count": 92
    },
    {
      "term": "DYSPNOEA EXERTIONAL",
      "count": 91
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 89
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 88
    },
    {
      "term": "FULL BLOOD COUNT ABNORMAL",
      "count": 88
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 87
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 86
    },
    {
      "term": "INFECTION",
      "count": 86
    },
    {
      "term": "ANXIETY",
      "count": 85
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 84
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 84
    }
  ]
}