{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DYSPNOEA",
      "count": 5459
    },
    {
      "term": "NAUSEA",
      "count": 5105
    },
    {
      "term": "NEUTROPENIA",
      "count": 4929
    },
    {
      "term": "OFF LABEL USE",
      "count": 4776
    },
    {
      "term": "DIARRHOEA",
      "count": 4645
    },
    {
      "term": "ANAEMIA",
      "count": 4208
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 3904
    },
    {
      "term": "FATIGUE",
      "count": 3618
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 3556
    },
    {
      "term": "VOMITING",
      "count": 3474
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 3472
    },
    {
      "term": "PYREXIA",
      "count": 3434
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 3312
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 3228
    },
    {
      "term": "ASTHENIA",
      "count": 2757
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 2626
    },
    {
      "term": "ERYTHEMA",
      "count": 2614
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 2540
    },
    {
      "term": "RASH",
      "count": 2303
    },
    {
      "term": "DEATH",
      "count": 2266
    },
    {
      "term": "HYPERTENSION",
      "count": 2013
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1997
    },
    {
      "term": "PNEUMONIA",
      "count": 1893
    },
    {
      "term": "BACK PAIN",
      "count": 1891
    },
    {
      "term": "FLUSHING",
      "count": 1875
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1833
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 1765
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 1737
    },
    {
      "term": "HYPOTENSION",
      "count": 1736
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 1667
    },
    {
      "term": "LEUKOPENIA",
      "count": 1644
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 1589
    },
    {
      "term": "MALAISE",
      "count": 1572
    },
    {
      "term": "ALOPECIA",
      "count": 1547
    },
    {
      "term": "COUGH",
      "count": 1516
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 1498
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 1462
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 1445
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 1418
    },
    {
      "term": "CONSTIPATION",
      "count": 1335
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1309
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 1236
    },
    {
      "term": "DEHYDRATION",
      "count": 1227
    },
    {
      "term": "CHEST PAIN",
      "count": 1224
    },
    {
      "term": "PNEUMONITIS",
      "count": 1221
    },
    {
      "term": "PAIN",
      "count": 1193
    },
    {
      "term": "DIZZINESS",
      "count": 1183
    },
    {
      "term": "PRURITUS",
      "count": 1182
    },
    {
      "term": "SEPSIS",
      "count": 1168
    },
    {
      "term": "PANCYTOPENIA",
      "count": 1166
    },
    {
      "term": "ARTHRALGIA",
      "count": 1154
    },
    {
      "term": "TACHYCARDIA",
      "count": 1116
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 1072
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 1065
    },
    {
      "term": "PARAESTHESIA",
      "count": 1062
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 1058
    },
    {
      "term": "HEADACHE",
      "count": 1051
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 1044
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 1023
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 1001
    },
    {
      "term": "EPISTAXIS",
      "count": 949
    },
    {
      "term": "METASTASES TO BONE",
      "count": 930
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 882
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 866
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 864
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 834
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 829
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 828
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 824
    },
    {
      "term": "HYPOXIA",
      "count": 816
    },
    {
      "term": "FEELING HOT",
      "count": 812
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 805
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 803
    },
    {
      "term": "STOMATITIS",
      "count": 801
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 799
    },
    {
      "term": "MYALGIA",
      "count": 797
    },
    {
      "term": "PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME",
      "count": 786
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 785
    },
    {
      "term": "INFECTION",
      "count": 784
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 781
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 774
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 750
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 748
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 726
    },
    {
      "term": "POLYNEUROPATHY",
      "count": 723
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 714
    },
    {
      "term": "COLITIS",
      "count": 708
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 706
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 704
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 704
    },
    {
      "term": "NEUROTOXICITY",
      "count": 703
    },
    {
      "term": "CHILLS",
      "count": 700
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 681
    },
    {
      "term": "HYPOTHYROIDISM",
      "count": 677
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 675
    },
    {
      "term": "ASCITES",
      "count": 658
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 653
    },
    {
      "term": "METASTASES TO CENTRAL NERVOUS SYSTEM",
      "count": 652
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 643
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 643
    }
  ]
}