{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEPENDENCE",
      "count": 4903
    },
    {
      "term": "DEATH",
      "count": 3324
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 2788
    },
    {
      "term": "OVERDOSE",
      "count": 2312
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 591
    },
    {
      "term": "DRUG ABUSE",
      "count": 584
    },
    {
      "term": "BACK PAIN",
      "count": 432
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME NEONATAL",
      "count": 350
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 331
    },
    {
      "term": "PAIN",
      "count": 316
    },
    {
      "term": "BACK INJURY",
      "count": 243
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 223
    },
    {
      "term": "DEPRESSION",
      "count": 203
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 203
    },
    {
      "term": "DEVELOPMENTAL DELAY",
      "count": 174
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 170
    },
    {
      "term": "ANXIETY",
      "count": 169
    },
    {
      "term": "DRUG DIVERSION",
      "count": 150
    },
    {
      "term": "ARTHRALGIA",
      "count": 135
    },
    {
      "term": "DYSPHAGIA",
      "count": 131
    },
    {
      "term": "ACCIDENTAL OVERDOSE",
      "count": 117
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 112
    },
    {
      "term": "ROAD TRAFFIC ACCIDENT",
      "count": 97
    },
    {
      "term": "ASTHMA",
      "count": 95
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 95
    },
    {
      "term": "SPEECH DISORDER DEVELOPMENTAL",
      "count": 94
    },
    {
      "term": "LEARNING DISORDER",
      "count": 90
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 89
    },
    {
      "term": "SPINAL OPERATION",
      "count": 80
    },
    {
      "term": "LEARNING DISABILITY",
      "count": 74
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 74
    },
    {
      "term": "NECK PAIN",
      "count": 73
    },
    {
      "term": "CARDIAC DISORDER",
      "count": 66
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 64
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 64
    },
    {
      "term": "PREMATURE BABY",
      "count": 59
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 57
    },
    {
      "term": "NAUSEA",
      "count": 57
    },
    {
      "term": "HEADACHE",
      "count": 56
    },
    {
      "term": "DISABILITY",
      "count": 55
    },
    {
      "term": "CONSTIPATION",
      "count": 53
    },
    {
      "term": "ATTENTION DEFICIT HYPERACTIVITY DISORDER",
      "count": 52
    },
    {
      "term": "DISTURBANCE IN ATTENTION",
      "count": 52
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 50
    },
    {
      "term": "INTERVERTEBRAL DISC PROTRUSION",
      "count": 49
    },
    {
      "term": "JOINT INJURY",
      "count": 49
    },
    {
      "term": "HYPOACUSIS",
      "count": 48
    },
    {
      "term": "VOMITING",
      "count": 45
    },
    {
      "term": "DYSPNOEA",
      "count": 41
    },
    {
      "term": "ARTHRITIS",
      "count": 40
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 39
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 38
    },
    {
      "term": "LIMB INJURY",
      "count": 38
    },
    {
      "term": "GAIT INABILITY",
      "count": 37
    },
    {
      "term": "FATIGUE",
      "count": 36
    },
    {
      "term": "INJURY",
      "count": 35
    },
    {
      "term": "KNEE OPERATION",
      "count": 35
    },
    {
      "term": "NECK INJURY",
      "count": 35
    },
    {
      "term": "MIGRAINE",
      "count": 34
    },
    {
      "term": "SPINAL CORD INJURY",
      "count": 33
    },
    {
      "term": "AMNESIA",
      "count": 32
    },
    {
      "term": "FALL",
      "count": 31
    },
    {
      "term": "POST-TRAUMATIC STRESS DISORDER",
      "count": 30
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 29
    },
    {
      "term": "INSOMNIA",
      "count": 29
    },
    {
      "term": "INTERVERTEBRAL DISC DEGENERATION",
      "count": 29
    },
    {
      "term": "MALAISE",
      "count": 29
    },
    {
      "term": "PRODUCT PRESCRIBING ISSUE",
      "count": 28
    },
    {
      "term": "FIBROMYALGIA",
      "count": 27
    },
    {
      "term": "DIZZINESS",
      "count": 25
    },
    {
      "term": "SEIZURE",
      "count": 25
    },
    {
      "term": "AUTISM SPECTRUM DISORDER",
      "count": 24
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 24
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 23
    },
    {
      "term": "SOMNOLENCE",
      "count": 22
    },
    {
      "term": "VISION ABNORMAL NEONATAL",
      "count": 22
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 21
    },
    {
      "term": "SPINAL FRACTURE",
      "count": 21
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 21
    },
    {
      "term": "SURGERY",
      "count": 21
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 20
    },
    {
      "term": "COGNITIVE DISORDER",
      "count": 19
    },
    {
      "term": "DRUG INTERACTION",
      "count": 19
    },
    {
      "term": "OFF LABEL USE",
      "count": 19
    },
    {
      "term": "BRAIN INJURY",
      "count": 18
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 18
    },
    {
      "term": "TOOTH DISORDER",
      "count": 18
    },
    {
      "term": "VISION BLURRED",
      "count": 18
    },
    {
      "term": "HYPOTENSION",
      "count": 17
    },
    {
      "term": "NEOPLASM MALIGNANT",
      "count": 17
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 17
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 16
    },
    {
      "term": "MENTAL DISORDER",
      "count": 16
    },
    {
      "term": "MULTIPLE DRUG OVERDOSE ACCIDENTAL",
      "count": 16
    },
    {
      "term": "TOOTHACHE",
      "count": 16
    },
    {
      "term": "BALANCE DISORDER",
      "count": 15
    },
    {
      "term": "COMA",
      "count": 15
    },
    {
      "term": "DIARRHOEA",
      "count": 15
    },
    {
      "term": "EXPOSURE VIA BREAST MILK",
      "count": 15
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 15
    }
  ]
}