{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEATH",
      "count": 660
    },
    {
      "term": "FATIGUE",
      "count": 604
    },
    {
      "term": "NAUSEA",
      "count": 535
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 503
    },
    {
      "term": "ANAEMIA",
      "count": 461
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 356
    },
    {
      "term": "OFF LABEL USE",
      "count": 290
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 257
    },
    {
      "term": "VOMITING",
      "count": 239
    },
    {
      "term": "DIARRHOEA",
      "count": 213
    },
    {
      "term": "ASTHENIA",
      "count": 209
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 201
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 179
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 173
    },
    {
      "term": "DECREASED APPETITE",
      "count": 170
    },
    {
      "term": "CONSTIPATION",
      "count": 167
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 163
    },
    {
      "term": "DYSPNOEA",
      "count": 125
    },
    {
      "term": "PAIN",
      "count": 120
    },
    {
      "term": "HEADACHE",
      "count": 118
    },
    {
      "term": "ARTHRALGIA",
      "count": 117
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 114
    },
    {
      "term": "NEUTROPENIA",
      "count": 111
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 109
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 107
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 104
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 104
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 96
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 95
    },
    {
      "term": "PANCYTOPENIA",
      "count": 91
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 83
    },
    {
      "term": "DIZZINESS",
      "count": 82
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 81
    },
    {
      "term": "PYREXIA",
      "count": 81
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 79
    },
    {
      "term": "PNEUMONIA",
      "count": 78
    },
    {
      "term": "METASTASES TO BONE",
      "count": 76
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 75
    },
    {
      "term": "DRUG INTERACTION",
      "count": 73
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 71
    },
    {
      "term": "HYPERTENSION",
      "count": 70
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 66
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 66
    },
    {
      "term": "RASH",
      "count": 66
    },
    {
      "term": "THROMBOSIS",
      "count": 66
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 66
    },
    {
      "term": "FALL",
      "count": 64
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 62
    },
    {
      "term": "PNEUMONITIS",
      "count": 60
    },
    {
      "term": "RENAL FAILURE",
      "count": 58
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 57
    },
    {
      "term": "MYALGIA",
      "count": 57
    },
    {
      "term": "PROSTATIC SPECIFIC ANTIGEN INCREASED",
      "count": 56
    },
    {
      "term": "BACK PAIN",
      "count": 54
    },
    {
      "term": "COUGH",
      "count": 54
    },
    {
      "term": "ASCITES",
      "count": 53
    },
    {
      "term": "PRURITUS",
      "count": 53
    },
    {
      "term": "DYSPEPSIA",
      "count": 51
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 51
    },
    {
      "term": "INFECTION",
      "count": 51
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 51
    },
    {
      "term": "OVARIAN CANCER RECURRENT",
      "count": 49
    },
    {
      "term": "DEHYDRATION",
      "count": 48
    },
    {
      "term": "MALAISE",
      "count": 48
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 47
    },
    {
      "term": "LEUKOPENIA",
      "count": 47
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 47
    },
    {
      "term": "SEPSIS",
      "count": 47
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 46
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 46
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 45
    },
    {
      "term": "RED BLOOD CELL COUNT DECREASED",
      "count": 45
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 44
    },
    {
      "term": "ILLNESS",
      "count": 44
    },
    {
      "term": "HYPOTENSION",
      "count": 43
    },
    {
      "term": "INSOMNIA",
      "count": 43
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 42
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 42
    },
    {
      "term": "ALOPECIA",
      "count": 41
    },
    {
      "term": "INTESTINAL OBSTRUCTION",
      "count": 41
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 41
    },
    {
      "term": "METASTASES TO CENTRAL NERVOUS SYSTEM",
      "count": 39
    },
    {
      "term": "UNDERDOSE",
      "count": 39
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 38
    },
    {
      "term": "NEOPLASM MALIGNANT",
      "count": 38
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 37
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 37
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 37
    },
    {
      "term": "LYMPHOPENIA",
      "count": 37
    },
    {
      "term": "PARAESTHESIA",
      "count": 37
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 36
    },
    {
      "term": "ANXIETY",
      "count": 36
    },
    {
      "term": "CARBOHYDRATE ANTIGEN 125 INCREASED",
      "count": 36
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 36
    },
    {
      "term": "BONE PAIN",
      "count": 35
    },
    {
      "term": "COVID-19",
      "count": 35
    },
    {
      "term": "FULL BLOOD COUNT DECREASED",
      "count": 35
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 34
    },
    {
      "term": "METASTASIS",
      "count": 34
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 32
    }
  ]
}