{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 848
    },
    {
      "term": "DIARRHOEA",
      "count": 832
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 810
    },
    {
      "term": "DEATH",
      "count": 575
    },
    {
      "term": "NAUSEA",
      "count": 569
    },
    {
      "term": "FATIGUE",
      "count": 507
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 404
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 382
    },
    {
      "term": "VOMITING",
      "count": 334
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 319
    },
    {
      "term": "DYSPNOEA",
      "count": 297
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 297
    },
    {
      "term": "PAIN",
      "count": 286
    },
    {
      "term": "ASTHENIA",
      "count": 281
    },
    {
      "term": "HEADACHE",
      "count": 267
    },
    {
      "term": "MALAISE",
      "count": 263
    },
    {
      "term": "DIZZINESS",
      "count": 248
    },
    {
      "term": "INJECTION SITE PAIN",
      "count": 241
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 240
    },
    {
      "term": "DECREASED APPETITE",
      "count": 237
    },
    {
      "term": "PYREXIA",
      "count": 233
    },
    {
      "term": "HYPOTENSION",
      "count": 218
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 213
    },
    {
      "term": "HYPOGLYCAEMIA",
      "count": 210
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 208
    },
    {
      "term": "FLUSHING",
      "count": 206
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 198
    },
    {
      "term": "FALL",
      "count": 193
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 181
    },
    {
      "term": "DEHYDRATION",
      "count": 177
    },
    {
      "term": "CONSTIPATION",
      "count": 175
    },
    {
      "term": "HYPERTENSION",
      "count": 175
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 172
    },
    {
      "term": "ANAEMIA",
      "count": 171
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 169
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 165
    },
    {
      "term": "PNEUMONIA",
      "count": 164
    },
    {
      "term": "BLOOD PRESSURE SYSTOLIC INCREASED",
      "count": 160
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 158
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 156
    },
    {
      "term": "ARTHRALGIA",
      "count": 150
    },
    {
      "term": "COUGH",
      "count": 148
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 145
    },
    {
      "term": "BACK PAIN",
      "count": 144
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 143
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 141
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 129
    },
    {
      "term": "SEPSIS",
      "count": 128
    },
    {
      "term": "FLATULENCE",
      "count": 126
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 126
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 121
    },
    {
      "term": "HOSPITALISATION",
      "count": 120
    },
    {
      "term": "DRUG INTERACTION",
      "count": 119
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 118
    },
    {
      "term": "INTESTINAL OBSTRUCTION",
      "count": 115
    },
    {
      "term": "CONTUSION",
      "count": 114
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 114
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 113
    },
    {
      "term": "CHEST PAIN",
      "count": 111
    },
    {
      "term": "RASH",
      "count": 107
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 105
    },
    {
      "term": "NEEDLE ISSUE",
      "count": 104
    },
    {
      "term": "ASCITES",
      "count": 102
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 101
    },
    {
      "term": "ANXIETY",
      "count": 100
    },
    {
      "term": "CHOLELITHIASIS",
      "count": 98
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 98
    },
    {
      "term": "RENAL FAILURE",
      "count": 98
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 96
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 95
    },
    {
      "term": "ERYTHEMA",
      "count": 94
    },
    {
      "term": "SYNCOPE",
      "count": 94
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 91
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 91
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 91
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 90
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 89
    },
    {
      "term": "HEART RATE DECREASED",
      "count": 88
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 86
    },
    {
      "term": "SOMNOLENCE",
      "count": 85
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 85
    },
    {
      "term": "BRADYCARDIA",
      "count": 84
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 82
    },
    {
      "term": "CARDIAC ARREST",
      "count": 82
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 82
    },
    {
      "term": "PRURITUS",
      "count": 81
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 78
    },
    {
      "term": "CARCINOID CRISIS",
      "count": 77
    },
    {
      "term": "NEUTROPENIA",
      "count": 77
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 77
    },
    {
      "term": "BODY TEMPERATURE DECREASED",
      "count": 74
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 74
    },
    {
      "term": "HAEMORRHAGE",
      "count": 73
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 73
    },
    {
      "term": "CHILLS",
      "count": 72
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 72
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 71
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 71
    },
    {
      "term": "INJECTION SITE MASS",
      "count": 70
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 70
    }
  ]
}