{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 19
    },
    {
      "term": "MALAISE",
      "count": 14
    },
    {
      "term": "NAUSEA",
      "count": 13
    },
    {
      "term": "DYSPNOEA",
      "count": 12
    },
    {
      "term": "DEATH",
      "count": 10
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 9
    },
    {
      "term": "FATIGUE",
      "count": 9
    },
    {
      "term": "PAIN",
      "count": 9
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 9
    },
    {
      "term": "ANXIETY",
      "count": 8
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 8
    },
    {
      "term": "SQUAMOUS CELL CARCINOMA OF SKIN",
      "count": 8
    },
    {
      "term": "ACCIDENTAL EXPOSURE TO PRODUCT",
      "count": 7
    },
    {
      "term": "ALOPECIA",
      "count": 7
    },
    {
      "term": "ASTHENIA",
      "count": 7
    },
    {
      "term": "CONSTIPATION",
      "count": 7
    },
    {
      "term": "DRUG INTERACTION",
      "count": 7
    },
    {
      "term": "PNEUMONIA",
      "count": 7
    },
    {
      "term": "PSORIASIS",
      "count": 7
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 7
    },
    {
      "term": "SEPSIS",
      "count": 7
    },
    {
      "term": "APPLICATION SITE ERYTHEMA",
      "count": 6
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 6
    },
    {
      "term": "ERYTHEMA",
      "count": 6
    },
    {
      "term": "EXTREMITY NECROSIS",
      "count": 6
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 6
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 6
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 6
    },
    {
      "term": "RASH",
      "count": 6
    },
    {
      "term": "SECOND PRIMARY MALIGNANCY",
      "count": 6
    },
    {
      "term": "CHEST PAIN",
      "count": 5
    },
    {
      "term": "DEHYDRATION",
      "count": 5
    },
    {
      "term": "DEPRESSION",
      "count": 5
    },
    {
      "term": "DRUG ADMINISTRATION ERROR",
      "count": 5
    },
    {
      "term": "HYPERTENSION",
      "count": 5
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 5
    },
    {
      "term": "PRODUCT LEAKAGE",
      "count": 5
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 5
    },
    {
      "term": "PYREXIA",
      "count": 5
    },
    {
      "term": "SQUAMOUS CELL CARCINOMA",
      "count": 5
    },
    {
      "term": "VOMITING",
      "count": 5
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 4
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 4
    },
    {
      "term": "BACK PAIN",
      "count": 4
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 4
    },
    {
      "term": "DECREASED APPETITE",
      "count": 4
    },
    {
      "term": "DIARRHOEA",
      "count": 4
    },
    {
      "term": "DIZZINESS",
      "count": 4
    },
    {
      "term": "DRY GANGRENE",
      "count": 4
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 4
    },
    {
      "term": "FALL",
      "count": 4
    },
    {
      "term": "HAEMODYNAMIC INSTABILITY",
      "count": 4
    },
    {
      "term": "INCORRECT DRUG ADMINISTRATION DURATION",
      "count": 4
    },
    {
      "term": "INJECTION SITE REACTION",
      "count": 4
    },
    {
      "term": "INSOMNIA",
      "count": 4
    },
    {
      "term": "MALIGNANT MELANOMA",
      "count": 4
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 4
    },
    {
      "term": "MENTAL STATUS CHANGES",
      "count": 4
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 4
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 4
    },
    {
      "term": "NEUTROPENIA",
      "count": 4
    },
    {
      "term": "PRURITUS",
      "count": 4
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 4
    },
    {
      "term": "SINUS TACHYCARDIA",
      "count": 4
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 4
    },
    {
      "term": "VENTRICULAR FIBRILLATION",
      "count": 4
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 3
    },
    {
      "term": "AIR EMBOLISM",
      "count": 3
    },
    {
      "term": "ANAEMIA",
      "count": 3
    },
    {
      "term": "ANGINA PECTORIS",
      "count": 3
    },
    {
      "term": "APPLICATION SITE PAIN",
      "count": 3
    },
    {
      "term": "APPLICATION SITE VESICLES",
      "count": 3
    },
    {
      "term": "ARTHRALGIA",
      "count": 3
    },
    {
      "term": "BASAL CELL CARCINOMA",
      "count": 3
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 3
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 3
    },
    {
      "term": "CARDIAC MURMUR",
      "count": 3
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 3
    },
    {
      "term": "CHILLS",
      "count": 3
    },
    {
      "term": "CHORIOCARCINOMA",
      "count": 3
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 3
    },
    {
      "term": "DIVERTICULITIS",
      "count": 3
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 3
    },
    {
      "term": "EYE IRRITATION",
      "count": 3
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 3
    },
    {
      "term": "GANGRENE",
      "count": 3
    },
    {
      "term": "HEMIPARESIS",
      "count": 3
    },
    {
      "term": "HODGKIN'S DISEASE",
      "count": 3
    },
    {
      "term": "HODGKIN^S DISEASE RECURRENT",
      "count": 3
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 3
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 3
    },
    {
      "term": "HYPOXIA",
      "count": 3
    },
    {
      "term": "INFECTION",
      "count": 3
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 3
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 3
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 3
    },
    {
      "term": "MUSCULOSKELETAL CHEST PAIN",
      "count": 3
    },
    {
      "term": "NECK PAIN",
      "count": 3
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 3
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 3
    }
  ]
}