{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DIARRHOEA",
      "count": 66
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 55
    },
    {
      "term": "OFF LABEL USE",
      "count": 51
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 45
    },
    {
      "term": "DYSPNOEA",
      "count": 39
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 32
    },
    {
      "term": "CHEST PAIN",
      "count": 31
    },
    {
      "term": "COMA SCALE ABNORMAL",
      "count": 31
    },
    {
      "term": "MICROSPORIDIA INFECTION",
      "count": 31
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII INFECTION",
      "count": 31
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 27
    },
    {
      "term": "NAUSEA",
      "count": 17
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 17
    },
    {
      "term": "CRYPTOSPORIDIOSIS INFECTION",
      "count": 16
    },
    {
      "term": "DRUG INTERACTION",
      "count": 16
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 15
    },
    {
      "term": "SEPSIS",
      "count": 15
    },
    {
      "term": "VOMITING",
      "count": 15
    },
    {
      "term": "GASTROENTERITIS NOROVIRUS",
      "count": 14
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 13
    },
    {
      "term": "NOROVIRUS INFECTION",
      "count": 12
    },
    {
      "term": "ANTICHOLINERGIC SYNDROME",
      "count": 11
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 11
    },
    {
      "term": "PYREXIA",
      "count": 11
    },
    {
      "term": "RENAL FAILURE",
      "count": 10
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 10
    },
    {
      "term": "ANAEMIA",
      "count": 9
    },
    {
      "term": "BK VIRUS INFECTION",
      "count": 9
    },
    {
      "term": "PARASITIC GASTROENTERITIS",
      "count": 9
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 8
    },
    {
      "term": "APLASTIC ANAEMIA",
      "count": 8
    },
    {
      "term": "HEADACHE",
      "count": 8
    },
    {
      "term": "PULMONARY TOXICITY",
      "count": 8
    },
    {
      "term": "VISION BLURRED",
      "count": 8
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 7
    },
    {
      "term": "ASTHENIA",
      "count": 7
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 7
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 7
    },
    {
      "term": "FATIGUE",
      "count": 7
    },
    {
      "term": "GASTROENTERITIS CRYPTOSPORIDIAL",
      "count": 7
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME",
      "count": 7
    },
    {
      "term": "MALAISE",
      "count": 7
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 7
    },
    {
      "term": "NEUTROPENIA",
      "count": 7
    },
    {
      "term": "PSEUDOMONAS INFECTION",
      "count": 7
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 7
    },
    {
      "term": "COLITIS",
      "count": 6
    },
    {
      "term": "CYSTITIS HAEMORRHAGIC",
      "count": 6
    },
    {
      "term": "DEHYDRATION",
      "count": 6
    },
    {
      "term": "DEPRESSION",
      "count": 6
    },
    {
      "term": "HYPOTENSION",
      "count": 6
    },
    {
      "term": "INFECTION",
      "count": 6
    },
    {
      "term": "LARGE INTESTINE PERFORATION",
      "count": 6
    },
    {
      "term": "LYMPHOPENIA",
      "count": 6
    },
    {
      "term": "PNEUMONIA",
      "count": 6
    },
    {
      "term": "PYELONEPHRITIS ACUTE",
      "count": 6
    },
    {
      "term": "STAPHYLOCOCCAL SEPSIS",
      "count": 6
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 6
    },
    {
      "term": "TRANSPLANT REJECTION",
      "count": 6
    },
    {
      "term": "CHORIOMENINGITIS LYMPHOCYTIC",
      "count": 5
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 5
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 5
    },
    {
      "term": "GIARDIASIS",
      "count": 5
    },
    {
      "term": "HERPES SIMPLEX VIRAEMIA",
      "count": 5
    },
    {
      "term": "MENTAL STATUS CHANGES",
      "count": 5
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 5
    },
    {
      "term": "SYSTEMIC CANDIDA",
      "count": 5
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 5
    },
    {
      "term": "WHEEZING",
      "count": 5
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 4
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 4
    },
    {
      "term": "CANDIDA SEPSIS",
      "count": 4
    },
    {
      "term": "CLONUS",
      "count": 4
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 4
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 4
    },
    {
      "term": "DRUG CLEARANCE DECREASED",
      "count": 4
    },
    {
      "term": "ELECTROLYTE IMBALANCE",
      "count": 4
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 4
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 4
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 4
    },
    {
      "term": "IMMUNOSUPPRESSANT DRUG LEVEL INCREASED",
      "count": 4
    },
    {
      "term": "MYDRIASIS",
      "count": 4
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 4
    },
    {
      "term": "PRURITUS",
      "count": 4
    },
    {
      "term": "RASH",
      "count": 4
    },
    {
      "term": "RENAL TUBULAR NECROSIS",
      "count": 4
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 4
    },
    {
      "term": "TRANSPLANT FAILURE",
      "count": 4
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 4
    },
    {
      "term": "ANXIETY",
      "count": 3
    },
    {
      "term": "ATRIOVENTRICULAR BLOCK COMPLETE",
      "count": 3
    },
    {
      "term": "AZOTAEMIA",
      "count": 3
    },
    {
      "term": "BILIARY TRACT INFECTION BACTERIAL",
      "count": 3
    },
    {
      "term": "CHOLESTASIS",
      "count": 3
    },
    {
      "term": "COUGH",
      "count": 3
    },
    {
      "term": "COVID-19",
      "count": 3
    },
    {
      "term": "COVID-19 PNEUMONIA",
      "count": 3
    },
    {
      "term": "DELIRIUM",
      "count": 3
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 3
    },
    {
      "term": "END STAGE RENAL DISEASE",
      "count": 3
    }
  ]
}