{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 2189
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1476
    },
    {
      "term": "DIARRHOEA",
      "count": 1061
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 891
    },
    {
      "term": "COVID-19",
      "count": 825
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 752
    },
    {
      "term": "PYREXIA",
      "count": 749
    },
    {
      "term": "NAUSEA",
      "count": 740
    },
    {
      "term": "DRUG INTERACTION",
      "count": 735
    },
    {
      "term": "DEATH",
      "count": 704
    },
    {
      "term": "FATIGUE",
      "count": 636
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 614
    },
    {
      "term": "PNEUMONIA",
      "count": 587
    },
    {
      "term": "HEADACHE",
      "count": 586
    },
    {
      "term": "DYSPNOEA",
      "count": 576
    },
    {
      "term": "VOMITING",
      "count": 568
    },
    {
      "term": "SEPSIS",
      "count": 545
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 508
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 473
    },
    {
      "term": "TRANSPLANT REJECTION",
      "count": 455
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 431
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 428
    },
    {
      "term": "COUGH",
      "count": 408
    },
    {
      "term": "ASTHENIA",
      "count": 404
    },
    {
      "term": "POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER",
      "count": 391
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 390
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 375
    },
    {
      "term": "NEUTROPENIA",
      "count": 370
    },
    {
      "term": "KIDNEY TRANSPLANT REJECTION",
      "count": 359
    },
    {
      "term": "ANAEMIA",
      "count": 354
    },
    {
      "term": "ARTHRALGIA",
      "count": 338
    },
    {
      "term": "LEUKOPENIA",
      "count": 338
    },
    {
      "term": "MALAISE",
      "count": 338
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 338
    },
    {
      "term": "DIZZINESS",
      "count": 336
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 329
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 326
    },
    {
      "term": "INFECTION",
      "count": 312
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 302
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 292
    },
    {
      "term": "DECREASED APPETITE",
      "count": 291
    },
    {
      "term": "RENAL FAILURE",
      "count": 286
    },
    {
      "term": "FALL",
      "count": 275
    },
    {
      "term": "CHILLS",
      "count": 269
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 266
    },
    {
      "term": "PRURITUS",
      "count": 257
    },
    {
      "term": "SOMNOLENCE",
      "count": 255
    },
    {
      "term": "HAEMATURIA",
      "count": 251
    },
    {
      "term": "PANCYTOPENIA",
      "count": 249
    },
    {
      "term": "TACHYCARDIA",
      "count": 244
    },
    {
      "term": "MYALGIA",
      "count": 241
    },
    {
      "term": "PAIN",
      "count": 241
    },
    {
      "term": "CYTOMEGALOVIRUS VIRAEMIA",
      "count": 238
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 236
    },
    {
      "term": "POLYOMAVIRUS-ASSOCIATED NEPHROPATHY",
      "count": 234
    },
    {
      "term": "COMA",
      "count": 224
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 224
    },
    {
      "term": "HYPERTENSION",
      "count": 222
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 218
    },
    {
      "term": "INSOMNIA",
      "count": 218
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 215
    },
    {
      "term": "THROMBOTIC MICROANGIOPATHY",
      "count": 212
    },
    {
      "term": "HYPOTENSION",
      "count": 208
    },
    {
      "term": "RASH",
      "count": 205
    },
    {
      "term": "VISION BLURRED",
      "count": 198
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 195
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 194
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 191
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 190
    },
    {
      "term": "ASCITES",
      "count": 189
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 189
    },
    {
      "term": "HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS",
      "count": 188
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 187
    },
    {
      "term": "HOSPITALISATION",
      "count": 186
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 185
    },
    {
      "term": "BK VIRUS INFECTION",
      "count": 184
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 183
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 182
    },
    {
      "term": "COMPLICATIONS OF TRANSPLANTED KIDNEY",
      "count": 180
    },
    {
      "term": "EPSTEIN-BARR VIRUS INFECTION",
      "count": 177
    },
    {
      "term": "SYNCOPE",
      "count": 170
    },
    {
      "term": "EYE PAIN",
      "count": 169
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 169
    },
    {
      "term": "POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME",
      "count": 169
    },
    {
      "term": "BLINDNESS",
      "count": 167
    },
    {
      "term": "PROTEINURIA",
      "count": 167
    },
    {
      "term": "TREMOR",
      "count": 166
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 165
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 164
    },
    {
      "term": "GENERALISED OEDEMA",
      "count": 163
    },
    {
      "term": "IMMUNOSUPPRESSANT DRUG LEVEL INCREASED",
      "count": 160
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 158
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 157
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 157
    },
    {
      "term": "DEHYDRATION",
      "count": 154
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 154
    },
    {
      "term": "DIPLOPIA",
      "count": 153
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 153
    },
    {
      "term": "HAEMATEMESIS",
      "count": 151
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 151
    }
  ]
}