{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 132
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 82
    },
    {
      "term": "ADRENAL INSUFFICIENCY",
      "count": 77
    },
    {
      "term": "NAUSEA",
      "count": 56
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 46
    },
    {
      "term": "NEUTROPENIA",
      "count": 46
    },
    {
      "term": "ANAEMIA",
      "count": 43
    },
    {
      "term": "DRUG INTERACTION",
      "count": 42
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 40
    },
    {
      "term": "ASTHENIA",
      "count": 37
    },
    {
      "term": "VOMITING",
      "count": 36
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 34
    },
    {
      "term": "FATIGUE",
      "count": 28
    },
    {
      "term": "DEATH",
      "count": 27
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 26
    },
    {
      "term": "ADRENOCORTICAL INSUFFICIENCY ACUTE",
      "count": 24
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 22
    },
    {
      "term": "PNEUMONIA",
      "count": 22
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 22
    },
    {
      "term": "DECREASED APPETITE",
      "count": 20
    },
    {
      "term": "PYREXIA",
      "count": 20
    },
    {
      "term": "HYPOTHYROIDISM",
      "count": 17
    },
    {
      "term": "CENTRAL HYPOTHYROIDISM",
      "count": 16
    },
    {
      "term": "MALNUTRITION",
      "count": 16
    },
    {
      "term": "GASTROINTESTINAL TOXICITY",
      "count": 15
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 15
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 14
    },
    {
      "term": "HYPOTENSION",
      "count": 14
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 14
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 14
    },
    {
      "term": "DEVICE RELATED INFECTION",
      "count": 13
    },
    {
      "term": "DIARRHOEA",
      "count": 13
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 13
    },
    {
      "term": "NEUROTOXICITY",
      "count": 13
    },
    {
      "term": "CARDIOMYOPATHY",
      "count": 12
    },
    {
      "term": "STOMATITIS",
      "count": 12
    },
    {
      "term": "ADRENOCORTICAL CARCINOMA",
      "count": 11
    },
    {
      "term": "HYPERCHOLESTEROLAEMIA",
      "count": 11
    },
    {
      "term": "SEPSIS",
      "count": 11
    },
    {
      "term": "CARDIOTOXICITY",
      "count": 10
    },
    {
      "term": "DIZZINESS",
      "count": 10
    },
    {
      "term": "DYSPNOEA",
      "count": 10
    },
    {
      "term": "GAMMA-GLUTAMYLTRANSFERASE INCREASED",
      "count": 10
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 10
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 10
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 10
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 10
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 10
    },
    {
      "term": "RENAL FAILURE",
      "count": 10
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 9
    },
    {
      "term": "DRUG CLEARANCE INCREASED",
      "count": 9
    },
    {
      "term": "GYNAECOMASTIA",
      "count": 9
    },
    {
      "term": "INFUSION SITE REACTION",
      "count": 9
    },
    {
      "term": "SOMNOLENCE",
      "count": 9
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 8
    },
    {
      "term": "BACTERAEMIA",
      "count": 8
    },
    {
      "term": "CARDIAC ARREST",
      "count": 8
    },
    {
      "term": "CYSTITIS HAEMORRHAGIC",
      "count": 8
    },
    {
      "term": "DISTURBANCE IN ATTENTION",
      "count": 8
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 8
    },
    {
      "term": "GASTROENTERITIS",
      "count": 8
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 8
    },
    {
      "term": "PRECOCIOUS PUBERTY",
      "count": 8
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 8
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 8
    },
    {
      "term": "VERTIGO",
      "count": 8
    },
    {
      "term": "ABDOMINAL ABSCESS",
      "count": 7
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 7
    },
    {
      "term": "COGNITIVE DISORDER",
      "count": 7
    },
    {
      "term": "HYPERADRENOCORTICISM",
      "count": 7
    },
    {
      "term": "HYPOXIA",
      "count": 7
    },
    {
      "term": "MALAISE",
      "count": 7
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 7
    },
    {
      "term": "PANCREATIC PSEUDOCYST",
      "count": 7
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 7
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 7
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 6
    },
    {
      "term": "BLEEDING TIME PROLONGED",
      "count": 6
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 6
    },
    {
      "term": "CUSHING^S SYNDROME",
      "count": 6
    },
    {
      "term": "DRUG CLEARANCE DECREASED",
      "count": 6
    },
    {
      "term": "GROWTH RETARDATION",
      "count": 6
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 6
    },
    {
      "term": "HYPOVOLAEMIC SHOCK",
      "count": 6
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 6
    },
    {
      "term": "OEDEMA",
      "count": 6
    },
    {
      "term": "PANCYTOPENIA",
      "count": 6
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 6
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 6
    },
    {
      "term": "ALOPECIA",
      "count": 5
    },
    {
      "term": "ATAXIA",
      "count": 5
    },
    {
      "term": "AUTOIMMUNE HEPATITIS",
      "count": 5
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 5
    },
    {
      "term": "CONSTIPATION",
      "count": 5
    },
    {
      "term": "DEAFNESS",
      "count": 5
    },
    {
      "term": "DEHYDRATION",
      "count": 5
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 5
    },
    {
      "term": "DYSGEUSIA",
      "count": 5
    },
    {
      "term": "HEADACHE",
      "count": 5
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 5
    }
  ]
}