{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1200
    },
    {
      "term": "OFF LABEL USE",
      "count": 1101
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 909
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 849
    },
    {
      "term": "PAIN",
      "count": 826
    },
    {
      "term": "NAUSEA",
      "count": 734
    },
    {
      "term": "ARTHRALGIA",
      "count": 708
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 706
    },
    {
      "term": "RASH",
      "count": 695
    },
    {
      "term": "JOINT SWELLING",
      "count": 687
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 649
    },
    {
      "term": "FATIGUE",
      "count": 647
    },
    {
      "term": "PNEUMONIA",
      "count": 640
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 633
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 620
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 607
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 606
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 595
    },
    {
      "term": "WOUND",
      "count": 595
    },
    {
      "term": "HEADACHE",
      "count": 587
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 585
    },
    {
      "term": "PERICARDITIS",
      "count": 584
    },
    {
      "term": "PEMPHIGUS",
      "count": 581
    },
    {
      "term": "SYNOVITIS",
      "count": 580
    },
    {
      "term": "MALAISE",
      "count": 560
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 558
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 540
    },
    {
      "term": "DIZZINESS",
      "count": 536
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 530
    },
    {
      "term": "ALOPECIA",
      "count": 529
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 527
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 524
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 520
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 513
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 495
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 495
    },
    {
      "term": "GLOSSODYNIA",
      "count": 491
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 489
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 483
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 482
    },
    {
      "term": "STOMATITIS",
      "count": 479
    },
    {
      "term": "SWELLING",
      "count": 476
    },
    {
      "term": "DIARRHOEA",
      "count": 474
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 471
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 468
    },
    {
      "term": "ARTHROPATHY",
      "count": 465
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 461
    },
    {
      "term": "HAND DEFORMITY",
      "count": 458
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 454
    },
    {
      "term": "DECREASED APPETITE",
      "count": 446
    },
    {
      "term": "HYPERTENSION",
      "count": 446
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 444
    },
    {
      "term": "VOMITING",
      "count": 444
    },
    {
      "term": "SLEEP DISORDER",
      "count": 443
    },
    {
      "term": "URTICARIA",
      "count": 439
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 438
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 429
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 407
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 401
    },
    {
      "term": "DYSPEPSIA",
      "count": 399
    },
    {
      "term": "FIBROMYALGIA",
      "count": 399
    },
    {
      "term": "DYSPNOEA",
      "count": 398
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 394
    },
    {
      "term": "FOLLICULITIS",
      "count": 390
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 389
    },
    {
      "term": "INJURY",
      "count": 372
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 372
    },
    {
      "term": "INSOMNIA",
      "count": 371
    },
    {
      "term": "BLISTER",
      "count": 365
    },
    {
      "term": "RED BLOOD CELL SEDIMENTATION RATE INCREASED",
      "count": 361
    },
    {
      "term": "HYPERCHOLESTEROLAEMIA",
      "count": 348
    },
    {
      "term": "LIVER INJURY",
      "count": 347
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 344
    },
    {
      "term": "ONYCHOMADESIS",
      "count": 340
    },
    {
      "term": "DEPRESSION",
      "count": 337
    },
    {
      "term": "GAIT INABILITY",
      "count": 335
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 334
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 333
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 333
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 332
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 328
    },
    {
      "term": "INFLAMMATION",
      "count": 325
    },
    {
      "term": "DRY MOUTH",
      "count": 321
    },
    {
      "term": "BURSITIS",
      "count": 314
    },
    {
      "term": "PYREXIA",
      "count": 314
    },
    {
      "term": "ASTHENIA",
      "count": 311
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 311
    },
    {
      "term": "WHEEZING",
      "count": 311
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 305
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 299
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 295
    },
    {
      "term": "ONYCHOMYCOSIS",
      "count": 292
    },
    {
      "term": "MIGRAINE",
      "count": 291
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 291
    },
    {
      "term": "OSTEOPOROSIS",
      "count": 291
    },
    {
      "term": "NIGHT SWEATS",
      "count": 290
    },
    {
      "term": "FACET JOINT SYNDROME",
      "count": 288
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 288
    },
    {
      "term": "PARAESTHESIA",
      "count": 286
    },
    {
      "term": "INFECTION",
      "count": 285
    }
  ]
}