{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 426
    },
    {
      "term": "OFF LABEL USE",
      "count": 297
    },
    {
      "term": "HYPOTENSION",
      "count": 264
    },
    {
      "term": "PYREXIA",
      "count": 182
    },
    {
      "term": "NAUSEA",
      "count": 166
    },
    {
      "term": "SEIZURE",
      "count": 151
    },
    {
      "term": "DRUG INTERACTION",
      "count": 133
    },
    {
      "term": "COLITIS",
      "count": 121
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 119
    },
    {
      "term": "ANAEMIA",
      "count": 119
    },
    {
      "term": "HEADACHE",
      "count": 117
    },
    {
      "term": "CONSTIPATION",
      "count": 114
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 110
    },
    {
      "term": "PAIN",
      "count": 109
    },
    {
      "term": "ERYTHEMA",
      "count": 108
    },
    {
      "term": "CARDIAC ARREST",
      "count": 107
    },
    {
      "term": "VOMITING",
      "count": 107
    },
    {
      "term": "FREQUENT BOWEL MOVEMENTS",
      "count": 97
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 96
    },
    {
      "term": "SOMNOLENCE",
      "count": 95
    },
    {
      "term": "HAEMATOCHEZIA",
      "count": 93
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 92
    },
    {
      "term": "MALAISE",
      "count": 91
    },
    {
      "term": "COLITIS ULCERATIVE",
      "count": 89
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 89
    },
    {
      "term": "DIARRHOEA",
      "count": 87
    },
    {
      "term": "DYSPNOEA",
      "count": 85
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 84
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 83
    },
    {
      "term": "RECTAL HAEMORRHAGE",
      "count": 81
    },
    {
      "term": "PROCTITIS",
      "count": 80
    },
    {
      "term": "TACHYCARDIA",
      "count": 78
    },
    {
      "term": "BRADYCARDIA",
      "count": 77
    },
    {
      "term": "FEMALE GENITAL TRACT FISTULA",
      "count": 77
    },
    {
      "term": "RADICULOPATHY",
      "count": 72
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 72
    },
    {
      "term": "ORAL CANDIDIASIS",
      "count": 71
    },
    {
      "term": "VAGINAL FLATULENCE",
      "count": 71
    },
    {
      "term": "DEATH",
      "count": 70
    },
    {
      "term": "VAGINAL DISCHARGE",
      "count": 68
    },
    {
      "term": "DIZZINESS",
      "count": 67
    },
    {
      "term": "PNEUMONIA",
      "count": 64
    },
    {
      "term": "ANXIETY",
      "count": 63
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 62
    },
    {
      "term": "DECREASED APPETITE",
      "count": 62
    },
    {
      "term": "HYPOXIA",
      "count": 62
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 60
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 60
    },
    {
      "term": "AGITATION",
      "count": 59
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 59
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 58
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 58
    },
    {
      "term": "STATUS EPILEPTICUS",
      "count": 57
    },
    {
      "term": "ARTHRALGIA",
      "count": 56
    },
    {
      "term": "RASH",
      "count": 56
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 56
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 55
    },
    {
      "term": "FATIGUE",
      "count": 54
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 54
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 53
    },
    {
      "term": "GENERALISED TONIC-CLONIC SEIZURE",
      "count": 53
    },
    {
      "term": "TROPONIN INCREASED",
      "count": 52
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 51
    },
    {
      "term": "PARAESTHESIA ORAL",
      "count": 50
    },
    {
      "term": "SEDATION",
      "count": 50
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 48
    },
    {
      "term": "RENAL FAILURE",
      "count": 48
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 48
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 47
    },
    {
      "term": "SEPSIS",
      "count": 47
    },
    {
      "term": "DYSPEPSIA",
      "count": 46
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 45
    },
    {
      "term": "CHRONIC SINUSITIS",
      "count": 45
    },
    {
      "term": "DELIRIUM",
      "count": 45
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 45
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 44
    },
    {
      "term": "OVERDOSE",
      "count": 44
    },
    {
      "term": "HYPERTENSION",
      "count": 43
    },
    {
      "term": "BLOOD POTASSIUM INCREASED",
      "count": 42
    },
    {
      "term": "DRUG ABUSE",
      "count": 42
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 42
    },
    {
      "term": "MACULAR DEGENERATION",
      "count": 42
    },
    {
      "term": "MYOCLONUS",
      "count": 42
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 42
    },
    {
      "term": "LEUKOCYTOSIS",
      "count": 41
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 41
    },
    {
      "term": "RESPIRATORY ARREST",
      "count": 40
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 38
    },
    {
      "term": "PROCEDURAL PAIN",
      "count": 38
    },
    {
      "term": "TREMOR",
      "count": 38
    },
    {
      "term": "TOXIC ENCEPHALOPATHY",
      "count": 37
    },
    {
      "term": "AMYLASE INCREASED",
      "count": 36
    },
    {
      "term": "ASTHENIA",
      "count": 36
    },
    {
      "term": "COMA",
      "count": 36
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 36
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 36
    },
    {
      "term": "MYOGLOBIN URINE PRESENT",
      "count": 36
    },
    {
      "term": "CROHN^S DISEASE",
      "count": 35
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 35
    },
    {
      "term": "SHOCK",
      "count": 35
    }
  ]
}