{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 3577
    },
    {
      "term": "OFF LABEL USE",
      "count": 2549
    },
    {
      "term": "HYPOTENSION",
      "count": 1928
    },
    {
      "term": "DRUG INTERACTION",
      "count": 1437
    },
    {
      "term": "SEIZURE",
      "count": 1176
    },
    {
      "term": "CARDIAC ARREST",
      "count": 1115
    },
    {
      "term": "PYREXIA",
      "count": 1087
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 965
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 939
    },
    {
      "term": "DEATH",
      "count": 850
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 814
    },
    {
      "term": "TACHYCARDIA",
      "count": 811
    },
    {
      "term": "NAUSEA",
      "count": 810
    },
    {
      "term": "PAIN",
      "count": 809
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 769
    },
    {
      "term": "RENAL FAILURE",
      "count": 753
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 740
    },
    {
      "term": "VOMITING",
      "count": 730
    },
    {
      "term": "DYSPNOEA",
      "count": 725
    },
    {
      "term": "BRADYCARDIA",
      "count": 717
    },
    {
      "term": "STATUS EPILEPTICUS",
      "count": 716
    },
    {
      "term": "PNEUMONIA",
      "count": 715
    },
    {
      "term": "AGITATION",
      "count": 676
    },
    {
      "term": "ANAEMIA",
      "count": 672
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 662
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 621
    },
    {
      "term": "SOMNOLENCE",
      "count": 617
    },
    {
      "term": "ANXIETY",
      "count": 615
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 594
    },
    {
      "term": "HYPOXIA",
      "count": 588
    },
    {
      "term": "DIARRHOEA",
      "count": 582
    },
    {
      "term": "OVERDOSE",
      "count": 576
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 571
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 562
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 548
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 530
    },
    {
      "term": "SEPSIS",
      "count": 520
    },
    {
      "term": "HEADACHE",
      "count": 506
    },
    {
      "term": "HYPERTENSION",
      "count": 503
    },
    {
      "term": "ERYTHEMA",
      "count": 489
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 472
    },
    {
      "term": "CONSTIPATION",
      "count": 460
    },
    {
      "term": "RASH",
      "count": 459
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 455
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 448
    },
    {
      "term": "COMA",
      "count": 440
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 438
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 436
    },
    {
      "term": "DELIRIUM",
      "count": 430
    },
    {
      "term": "MALAISE",
      "count": 429
    },
    {
      "term": "FATIGUE",
      "count": 417
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 406
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 388
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 384
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 382
    },
    {
      "term": "UNRESPONSIVE TO STIMULI",
      "count": 380
    },
    {
      "term": "ASTHENIA",
      "count": 365
    },
    {
      "term": "COLITIS",
      "count": 363
    },
    {
      "term": "GENERALISED TONIC-CLONIC SEIZURE",
      "count": 355
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 348
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 346
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 345
    },
    {
      "term": "DIZZINESS",
      "count": 333
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 324
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 320
    },
    {
      "term": "MYOCLONUS",
      "count": 318
    },
    {
      "term": "DRUG ABUSE",
      "count": 314
    },
    {
      "term": "INSOMNIA",
      "count": 308
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 306
    },
    {
      "term": "DECREASED APPETITE",
      "count": 300
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 298
    },
    {
      "term": "DEPRESSION",
      "count": 297
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 294
    },
    {
      "term": "MULTIPLE-DRUG RESISTANCE",
      "count": 293
    },
    {
      "term": "INJURY",
      "count": 292
    },
    {
      "term": "SHOCK",
      "count": 290
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 283
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 283
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 282
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 281
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 279
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 278
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 278
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 278
    },
    {
      "term": "TREMOR",
      "count": 277
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 276
    },
    {
      "term": "EPILEPSY",
      "count": 274
    },
    {
      "term": "CIRCULATORY COLLAPSE",
      "count": 273
    },
    {
      "term": "RESPIRATORY ARREST",
      "count": 273
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 271
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 269
    },
    {
      "term": "COLITIS ULCERATIVE",
      "count": 265
    },
    {
      "term": "ARTHRALGIA",
      "count": 264
    },
    {
      "term": "SEDATION",
      "count": 262
    },
    {
      "term": "FALL",
      "count": 261
    },
    {
      "term": "URTICARIA",
      "count": 261
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 257
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 253
    },
    {
      "term": "FREQUENT BOWEL MOVEMENTS",
      "count": 252
    },
    {
      "term": "HAEMATOCHEZIA",
      "count": 252
    }
  ]
}