{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 4788
    },
    {
      "term": "NAUSEA",
      "count": 3691
    },
    {
      "term": "OFF LABEL USE",
      "count": 3394
    },
    {
      "term": "DIARRHOEA",
      "count": 2915
    },
    {
      "term": "VOMITING",
      "count": 2465
    },
    {
      "term": "HEADACHE",
      "count": 2448
    },
    {
      "term": "PYREXIA",
      "count": 2438
    },
    {
      "term": "PAIN",
      "count": 2253
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 2184
    },
    {
      "term": "FATIGUE",
      "count": 2083
    },
    {
      "term": "DIZZINESS",
      "count": 1870
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 1732
    },
    {
      "term": "DYSPNOEA",
      "count": 1685
    },
    {
      "term": "MALAISE",
      "count": 1618
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 1561
    },
    {
      "term": "RASH",
      "count": 1517
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 1336
    },
    {
      "term": "ASTHENIA",
      "count": 1318
    },
    {
      "term": "ANAEMIA",
      "count": 1312
    },
    {
      "term": "ANXIETY",
      "count": 1287
    },
    {
      "term": "PRURITUS",
      "count": 1278
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1268
    },
    {
      "term": "ARTHRALGIA",
      "count": 1233
    },
    {
      "term": "RENAL FAILURE",
      "count": 1227
    },
    {
      "term": "SEPSIS",
      "count": 1197
    },
    {
      "term": "CONSTIPATION",
      "count": 1191
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 1184
    },
    {
      "term": "DRUG INTERACTION",
      "count": 1165
    },
    {
      "term": "ERYTHEMA",
      "count": 1089
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1068
    },
    {
      "term": "PNEUMONIA",
      "count": 1037
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 951
    },
    {
      "term": "PARAESTHESIA",
      "count": 947
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE INFECTION",
      "count": 936
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 908
    },
    {
      "term": "HYPOTENSION",
      "count": 908
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 896
    },
    {
      "term": "DECREASED APPETITE",
      "count": 894
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 873
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 864
    },
    {
      "term": "MACULAR DEGENERATION",
      "count": 860
    },
    {
      "term": "DEATH",
      "count": 834
    },
    {
      "term": "COLITIS",
      "count": 814
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 764
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 745
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 743
    },
    {
      "term": "DEPRESSION",
      "count": 742
    },
    {
      "term": "SOMNOLENCE",
      "count": 741
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 737
    },
    {
      "term": "INFECTION",
      "count": 727
    },
    {
      "term": "HYPERTENSION",
      "count": 714
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 702
    },
    {
      "term": "INSOMNIA",
      "count": 700
    },
    {
      "term": "BACK PAIN",
      "count": 685
    },
    {
      "term": "URTICARIA",
      "count": 685
    },
    {
      "term": "HAEMATOCHEZIA",
      "count": 682
    },
    {
      "term": "TOXIC ENCEPHALOPATHY",
      "count": 677
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 671
    },
    {
      "term": "NEUTROPENIA",
      "count": 667
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 663
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 661
    },
    {
      "term": "COUGH",
      "count": 658
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 657
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 647
    },
    {
      "term": "FALL",
      "count": 624
    },
    {
      "term": "DYSPEPSIA",
      "count": 622
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 621
    },
    {
      "term": "SWELLING FACE",
      "count": 618
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 617
    },
    {
      "term": "CHEST PAIN",
      "count": 615
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 613
    },
    {
      "term": "NEUROTOXICITY",
      "count": 602
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 592
    },
    {
      "term": "TREMOR",
      "count": 579
    },
    {
      "term": "CROHN^S DISEASE",
      "count": 572
    },
    {
      "term": "MYALGIA",
      "count": 558
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 545
    },
    {
      "term": "SWELLING",
      "count": 544
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 538
    },
    {
      "term": "TACHYCARDIA",
      "count": 538
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 537
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 531
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 531
    },
    {
      "term": "DEHYDRATION",
      "count": 527
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 521
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 521
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 520
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 519
    },
    {
      "term": "DYSGEUSIA",
      "count": 518
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 517
    },
    {
      "term": "END STAGE RENAL DISEASE",
      "count": 510
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 505
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 501
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 500
    },
    {
      "term": "RECTAL HAEMORRHAGE",
      "count": 500
    },
    {
      "term": "COLITIS ULCERATIVE",
      "count": 494
    },
    {
      "term": "ASCITES",
      "count": 479
    },
    {
      "term": "DYSARTHRIA",
      "count": 479
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 478
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 473
    }
  ]
}