{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 21675
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 15805
    },
    {
      "term": "FATIGUE",
      "count": 7548
    },
    {
      "term": "PAIN",
      "count": 7262
    },
    {
      "term": "HEADACHE",
      "count": 6984
    },
    {
      "term": "NAUSEA",
      "count": 6922
    },
    {
      "term": "PYREXIA",
      "count": 6727
    },
    {
      "term": "PNEUMONIA",
      "count": 6588
    },
    {
      "term": "ARTHRALGIA",
      "count": 6118
    },
    {
      "term": "DIARRHOEA",
      "count": 5915
    },
    {
      "term": "DYSPNOEA",
      "count": 5901
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 5881
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 5876
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 5568
    },
    {
      "term": "RASH",
      "count": 5241
    },
    {
      "term": "HYPERTENSION",
      "count": 5178
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 4800
    },
    {
      "term": "VOMITING",
      "count": 4448
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 4132
    },
    {
      "term": "MALAISE",
      "count": 4075
    },
    {
      "term": "COUGH",
      "count": 3978
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 3937
    },
    {
      "term": "ASTHENIA",
      "count": 3907
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 3867
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 3768
    },
    {
      "term": "DIZZINESS",
      "count": 3766
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 3662
    },
    {
      "term": "JOINT SWELLING",
      "count": 3520
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 3459
    },
    {
      "term": "PRURITUS",
      "count": 3418
    },
    {
      "term": "HYPOTENSION",
      "count": 3276
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 3071
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 3024
    },
    {
      "term": "INFECTION",
      "count": 3008
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 2981
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 2915
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 2914
    },
    {
      "term": "ERYTHEMA",
      "count": 2883
    },
    {
      "term": "SEPSIS",
      "count": 2860
    },
    {
      "term": "COVID-19",
      "count": 2844
    },
    {
      "term": "FALL",
      "count": 2730
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 2709
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 2656
    },
    {
      "term": "BACK PAIN",
      "count": 2638
    },
    {
      "term": "DEATH",
      "count": 2612
    },
    {
      "term": "ANAEMIA",
      "count": 2608
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 2542
    },
    {
      "term": "URTICARIA",
      "count": 2537
    },
    {
      "term": "ANXIETY",
      "count": 2525
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 2482
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 2481
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 2440
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 2439
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 2426
    },
    {
      "term": "BLOOD PRESSURE FLUCTUATION",
      "count": 2374
    },
    {
      "term": "BLOOD PRESSURE SYSTOLIC INCREASED",
      "count": 2370
    },
    {
      "term": "DEPRESSION",
      "count": 2370
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 2370
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 2354
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 2345
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 2325
    },
    {
      "term": "INSOMNIA",
      "count": 2320
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 2310
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 2278
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 2247
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 2217
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 2164
    },
    {
      "term": "DECREASED APPETITE",
      "count": 2161
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 2157
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 2157
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 2125
    },
    {
      "term": "SINUSITIS",
      "count": 2110
    },
    {
      "term": "NEUTROPENIA",
      "count": 2081
    },
    {
      "term": "RENAL FAILURE",
      "count": 2029
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 1985
    },
    {
      "term": "PARAESTHESIA",
      "count": 1954
    },
    {
      "term": "CHEST PAIN",
      "count": 1925
    },
    {
      "term": "ALOPECIA",
      "count": 1903
    },
    {
      "term": "SWELLING",
      "count": 1885
    },
    {
      "term": "DRUG INTERACTION",
      "count": 1880
    },
    {
      "term": "ARTHROPATHY",
      "count": 1843
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 1803
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 1801
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 1788
    },
    {
      "term": "HEART RATE DECREASED",
      "count": 1779
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 1756
    },
    {
      "term": "ASTHMA",
      "count": 1739
    },
    {
      "term": "CONSTIPATION",
      "count": 1739
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 1736
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 1699
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 1668
    },
    {
      "term": "INFLAMMATION",
      "count": 1665
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 1630
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 1630
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 1628
    },
    {
      "term": "PEMPHIGUS",
      "count": 1608
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 1605
    },
    {
      "term": "DYSPEPSIA",
      "count": 1595
    },
    {
      "term": "TACHYCARDIA",
      "count": 1591
    },
    {
      "term": "THROAT IRRITATION",
      "count": 1587
    }
  ]
}