{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1393
    },
    {
      "term": "HEADACHE",
      "count": 470
    },
    {
      "term": "ANXIETY",
      "count": 434
    },
    {
      "term": "FATIGUE",
      "count": 419
    },
    {
      "term": "NAUSEA",
      "count": 376
    },
    {
      "term": "PRODUCT SUBSTITUTION ISSUE",
      "count": 360
    },
    {
      "term": "OFF LABEL USE",
      "count": 353
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 325
    },
    {
      "term": "SOMNOLENCE",
      "count": 308
    },
    {
      "term": "DISTURBANCE IN ATTENTION",
      "count": 306
    },
    {
      "term": "INSOMNIA",
      "count": 304
    },
    {
      "term": "DRUG ABUSE",
      "count": 288
    },
    {
      "term": "DECREASED APPETITE",
      "count": 266
    },
    {
      "term": "AGITATION",
      "count": 254
    },
    {
      "term": "DIZZINESS",
      "count": 254
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 234
    },
    {
      "term": "DEPRESSION",
      "count": 232
    },
    {
      "term": "SUICIDAL IDEATION",
      "count": 232
    },
    {
      "term": "AGGRESSION",
      "count": 216
    },
    {
      "term": "IRRITABILITY",
      "count": 215
    },
    {
      "term": "VOMITING",
      "count": 212
    },
    {
      "term": "DRUG INTERACTION",
      "count": 193
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 188
    },
    {
      "term": "TACHYCARDIA",
      "count": 178
    },
    {
      "term": "PALPITATIONS",
      "count": 172
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 166
    },
    {
      "term": "OVERDOSE",
      "count": 162
    },
    {
      "term": "ABNORMAL BEHAVIOUR",
      "count": 154
    },
    {
      "term": "DIARRHOEA",
      "count": 154
    },
    {
      "term": "HYPERTENSION",
      "count": 151
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 144
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 138
    },
    {
      "term": "PAIN",
      "count": 137
    },
    {
      "term": "TREMOR",
      "count": 136
    },
    {
      "term": "DRUG EFFECT DECREASED",
      "count": 135
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 134
    },
    {
      "term": "DYSPNOEA",
      "count": 131
    },
    {
      "term": "MALAISE",
      "count": 127
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 126
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 125
    },
    {
      "term": "HOSPITALISATION",
      "count": 123
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 123
    },
    {
      "term": "ASTHENIA",
      "count": 122
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 122
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 121
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 117
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 115
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 112
    },
    {
      "term": "ANGER",
      "count": 108
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 108
    },
    {
      "term": "DYSTONIA",
      "count": 107
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 106
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 103
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 103
    },
    {
      "term": "CHEST PAIN",
      "count": 100
    },
    {
      "term": "DEPRESSED MOOD",
      "count": 100
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 95
    },
    {
      "term": "PSYCHOMOTOR HYPERACTIVITY",
      "count": 95
    },
    {
      "term": "FALL",
      "count": 93
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 92
    },
    {
      "term": "VISION BLURRED",
      "count": 91
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 91
    },
    {
      "term": "DYSKINESIA",
      "count": 90
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 90
    },
    {
      "term": "PRURITUS",
      "count": 90
    },
    {
      "term": "ARTHRALGIA",
      "count": 89
    },
    {
      "term": "RASH",
      "count": 89
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 86
    },
    {
      "term": "PARAESTHESIA",
      "count": 86
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 83
    },
    {
      "term": "SLEEP DISORDER",
      "count": 83
    },
    {
      "term": "ADVERSE DRUG REACTION",
      "count": 80
    },
    {
      "term": "MOOD SWINGS",
      "count": 78
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 77
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 77
    },
    {
      "term": "INTENTIONAL OVERDOSE",
      "count": 77
    },
    {
      "term": "DEATH",
      "count": 75
    },
    {
      "term": "MIGRAINE",
      "count": 75
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 74
    },
    {
      "term": "PSYCHOTIC DISORDER",
      "count": 74
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 74
    },
    {
      "term": "DRUG DOSE OMISSION",
      "count": 72
    },
    {
      "term": "EMOTIONAL DISORDER",
      "count": 72
    },
    {
      "term": "HYPOTENSION",
      "count": 72
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 72
    },
    {
      "term": "COUGH",
      "count": 70
    },
    {
      "term": "RESTLESSNESS",
      "count": 70
    },
    {
      "term": "HALLUCINATION",
      "count": 69
    },
    {
      "term": "LETHARGY",
      "count": 69
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 69
    },
    {
      "term": "ADVERSE EVENT",
      "count": 68
    },
    {
      "term": "CONSTIPATION",
      "count": 68
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 68
    },
    {
      "term": "SEIZURE",
      "count": 68
    },
    {
      "term": "PNEUMONIA",
      "count": 65
    },
    {
      "term": "PYREXIA",
      "count": 65
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 65
    },
    {
      "term": "CRYING",
      "count": 63
    },
    {
      "term": "PRODUCT AVAILABILITY ISSUE",
      "count": 63
    },
    {
      "term": "TIC",
      "count": 62
    }
  ]
}