{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 94765
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 43704
    },
    {
      "term": "ARTHRALGIA",
      "count": 41213
    },
    {
      "term": "PAIN",
      "count": 40128
    },
    {
      "term": "OFF LABEL USE",
      "count": 39626
    },
    {
      "term": "FATIGUE",
      "count": 33368
    },
    {
      "term": "NAUSEA",
      "count": 29458
    },
    {
      "term": "JOINT SWELLING",
      "count": 25265
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 25213
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 23851
    },
    {
      "term": "HEADACHE",
      "count": 23723
    },
    {
      "term": "RASH",
      "count": 22540
    },
    {
      "term": "DIARRHOEA",
      "count": 21144
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 20376
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 19862
    },
    {
      "term": "PYREXIA",
      "count": 19136
    },
    {
      "term": "PNEUMONIA",
      "count": 18588
    },
    {
      "term": "MALAISE",
      "count": 17697
    },
    {
      "term": "VOMITING",
      "count": 17695
    },
    {
      "term": "ALOPECIA",
      "count": 17448
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 17428
    },
    {
      "term": "DYSPNOEA",
      "count": 16559
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 16287
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 15691
    },
    {
      "term": "INFECTION",
      "count": 15300
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 15212
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 14983
    },
    {
      "term": "ARTHROPATHY",
      "count": 14700
    },
    {
      "term": "INJECTION SITE PAIN",
      "count": 14405
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 14362
    },
    {
      "term": "SYNOVITIS",
      "count": 13656
    },
    {
      "term": "SWELLING",
      "count": 13652
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 13179
    },
    {
      "term": "PRURITUS",
      "count": 12523
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 12282
    },
    {
      "term": "COUGH",
      "count": 12092
    },
    {
      "term": "HYPERTENSION",
      "count": 12024
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 12022
    },
    {
      "term": "ASTHENIA",
      "count": 11956
    },
    {
      "term": "DIZZINESS",
      "count": 11940
    },
    {
      "term": "PSORIASIS",
      "count": 11733
    },
    {
      "term": "SINUSITIS",
      "count": 11541
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 11536
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 11279
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 11028
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 10869
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 10860
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 10853
    },
    {
      "term": "FALL",
      "count": 10724
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 10553
    },
    {
      "term": "BACK PAIN",
      "count": 10322
    },
    {
      "term": "ARTHRITIS",
      "count": 10233
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 9849
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 9504
    },
    {
      "term": "PEMPHIGUS",
      "count": 9258
    },
    {
      "term": "STOMATITIS",
      "count": 9257
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 9035
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 8906
    },
    {
      "term": "HAND DEFORMITY",
      "count": 8809
    },
    {
      "term": "GLOSSODYNIA",
      "count": 8611
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 8367
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 8322
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 8186
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 8164
    },
    {
      "term": "WOUND",
      "count": 8097
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 8086
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 8024
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 7994
    },
    {
      "term": "INFLAMMATION",
      "count": 7952
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 7947
    },
    {
      "term": "INSOMNIA",
      "count": 7944
    },
    {
      "term": "URTICARIA",
      "count": 7631
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 7596
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 7406
    },
    {
      "term": "DISCOMFORT",
      "count": 7325
    },
    {
      "term": "PANCYTOPENIA",
      "count": 7183
    },
    {
      "term": "SEPSIS",
      "count": 7114
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 6958
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 6931
    },
    {
      "term": "ANAEMIA",
      "count": 6851
    },
    {
      "term": "DECREASED APPETITE",
      "count": 6821
    },
    {
      "term": "DEPRESSION",
      "count": 6744
    },
    {
      "term": "PERICARDITIS",
      "count": 6730
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 6658
    },
    {
      "term": "CHEST PAIN",
      "count": 6499
    },
    {
      "term": "CONTUSION",
      "count": 6473
    },
    {
      "term": "MUSCULOSKELETAL PAIN",
      "count": 6426
    },
    {
      "term": "INJECTION SITE ERYTHEMA",
      "count": 6414
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 6395
    },
    {
      "term": "BLISTER",
      "count": 6393
    },
    {
      "term": "NEUTROPENIA",
      "count": 6384
    },
    {
      "term": "ERYTHEMA",
      "count": 6346
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 6187
    },
    {
      "term": "COVID-19",
      "count": 6032
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 5991
    },
    {
      "term": "INFLUENZA",
      "count": 5935
    },
    {
      "term": "DEATH",
      "count": 5874
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 5708
    },
    {
      "term": "ANXIETY",
      "count": 5617
    },
    {
      "term": "FIBROMYALGIA",
      "count": 5605
    }
  ]
}