{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 6209
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 5870
    },
    {
      "term": "DRUG ABUSE",
      "count": 5478
    },
    {
      "term": "OVERDOSE",
      "count": 4306
    },
    {
      "term": "PAIN",
      "count": 4079
    },
    {
      "term": "DEATH",
      "count": 3953
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 2544
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 2418
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 2104
    },
    {
      "term": "NAUSEA",
      "count": 2100
    },
    {
      "term": "DRUG INTERACTION",
      "count": 2038
    },
    {
      "term": "CARDIAC ARREST",
      "count": 1823
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 1745
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 1736
    },
    {
      "term": "FATIGUE",
      "count": 1647
    },
    {
      "term": "VOMITING",
      "count": 1598
    },
    {
      "term": "SOMNOLENCE",
      "count": 1584
    },
    {
      "term": "ANXIETY",
      "count": 1577
    },
    {
      "term": "RESPIRATORY ARREST",
      "count": 1500
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME NEONATAL",
      "count": 1464
    },
    {
      "term": "OFF LABEL USE",
      "count": 1352
    },
    {
      "term": "DYSPNOEA",
      "count": 1264
    },
    {
      "term": "HEADACHE",
      "count": 1219
    },
    {
      "term": "DEPRESSION",
      "count": 1188
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 1127
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 1120
    },
    {
      "term": "PNEUMONIA",
      "count": 1086
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 1074
    },
    {
      "term": "COMA",
      "count": 1039
    },
    {
      "term": "DIARRHOEA",
      "count": 1023
    },
    {
      "term": "CONSTIPATION",
      "count": 953
    },
    {
      "term": "MALAISE",
      "count": 935
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 933
    },
    {
      "term": "DEPENDENCE",
      "count": 923
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 888
    },
    {
      "term": "FALL",
      "count": 881
    },
    {
      "term": "INSOMNIA",
      "count": 861
    },
    {
      "term": "ASTHENIA",
      "count": 839
    },
    {
      "term": "DIZZINESS",
      "count": 820
    },
    {
      "term": "DEVELOPMENTAL DELAY",
      "count": 807
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 785
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 770
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 757
    },
    {
      "term": "POISONING",
      "count": 757
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 756
    },
    {
      "term": "ARTHRALGIA",
      "count": 749
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 722
    },
    {
      "term": "PYREXIA",
      "count": 720
    },
    {
      "term": "BACK PAIN",
      "count": 675
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 668
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 665
    },
    {
      "term": "LEARNING DISABILITY",
      "count": 656
    },
    {
      "term": "HYPOTENSION",
      "count": 652
    },
    {
      "term": "ACCIDENTAL OVERDOSE",
      "count": 640
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 635
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 619
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 618
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 599
    },
    {
      "term": "TREMOR",
      "count": 593
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 568
    },
    {
      "term": "TORSADE DE POINTES",
      "count": 568
    },
    {
      "term": "HYPERTENSION",
      "count": 567
    },
    {
      "term": "DELIRIUM",
      "count": 562
    },
    {
      "term": "SUICIDAL IDEATION",
      "count": 561
    },
    {
      "term": "AGITATION",
      "count": 559
    },
    {
      "term": "DISABILITY",
      "count": 549
    },
    {
      "term": "RASH",
      "count": 549
    },
    {
      "term": "DECREASED APPETITE",
      "count": 544
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 526
    },
    {
      "term": "DRUG TOXICITY",
      "count": 525
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 509
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 500
    },
    {
      "term": "ANAEMIA",
      "count": 499
    },
    {
      "term": "MIOSIS",
      "count": 499
    },
    {
      "term": "CHEST PAIN",
      "count": 491
    },
    {
      "term": "UNRESPONSIVE TO STIMULI",
      "count": 489
    },
    {
      "term": "SUBSTANCE ABUSE",
      "count": 479
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 453
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 453
    },
    {
      "term": "INTENTIONAL OVERDOSE",
      "count": 445
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 441
    },
    {
      "term": "MENTAL DISORDER",
      "count": 439
    },
    {
      "term": "TACHYCARDIA",
      "count": 438
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 437
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 436
    },
    {
      "term": "RENAL FAILURE",
      "count": 435
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 414
    },
    {
      "term": "SEDATION",
      "count": 414
    },
    {
      "term": "SEIZURE",
      "count": 409
    },
    {
      "term": "INTENTIONAL DRUG MISUSE",
      "count": 405
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 396
    },
    {
      "term": "PRURITUS",
      "count": 390
    },
    {
      "term": "INJURY",
      "count": 382
    },
    {
      "term": "DEHYDRATION",
      "count": 377
    },
    {
      "term": "HALLUCINATION",
      "count": 374
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 374
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 364
    },
    {
      "term": "LETHARGY",
      "count": 363
    },
    {
      "term": "PNEUMONIA ASPIRATION",
      "count": 363
    },
    {
      "term": "MULTIPLE DRUG OVERDOSE",
      "count": 360
    }
  ]
}