{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 1370
    },
    {
      "term": "PYREXIA",
      "count": 706
    },
    {
      "term": "OFF LABEL USE",
      "count": 653
    },
    {
      "term": "NEUTROPENIA",
      "count": 591
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 406
    },
    {
      "term": "ANAEMIA",
      "count": 393
    },
    {
      "term": "VOMITING",
      "count": 381
    },
    {
      "term": "SEPSIS",
      "count": 376
    },
    {
      "term": "PANCYTOPENIA",
      "count": 371
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 369
    },
    {
      "term": "NAUSEA",
      "count": 366
    },
    {
      "term": "CYSTITIS HAEMORRHAGIC",
      "count": 358
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 357
    },
    {
      "term": "DIARRHOEA",
      "count": 355
    },
    {
      "term": "PNEUMONIA",
      "count": 293
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 285
    },
    {
      "term": "DEATH",
      "count": 259
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 229
    },
    {
      "term": "HYPOTENSION",
      "count": 228
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 227
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 219
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 217
    },
    {
      "term": "LEUKOPENIA",
      "count": 206
    },
    {
      "term": "INFECTION",
      "count": 203
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 201
    },
    {
      "term": "FATIGUE",
      "count": 182
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 181
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 179
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 173
    },
    {
      "term": "DYSPNOEA",
      "count": 173
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 166
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 158
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 156
    },
    {
      "term": "HEADACHE",
      "count": 154
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 154
    },
    {
      "term": "NEUROTOXICITY",
      "count": 154
    },
    {
      "term": "PAIN",
      "count": 152
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 148
    },
    {
      "term": "STOMATITIS",
      "count": 144
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 137
    },
    {
      "term": "HYPERTENSION",
      "count": 132
    },
    {
      "term": "VIRAL INFECTION",
      "count": 132
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 131
    },
    {
      "term": "TACHYCARDIA",
      "count": 131
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 128
    },
    {
      "term": "DRUG INTERACTION",
      "count": 127
    },
    {
      "term": "PSEUDOMONAL SEPSIS",
      "count": 127
    },
    {
      "term": "DECREASED APPETITE",
      "count": 125
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 125
    },
    {
      "term": "RENAL FAILURE",
      "count": 120
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 118
    },
    {
      "term": "CHILLS",
      "count": 117
    },
    {
      "term": "ASTHENIA",
      "count": 116
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 113
    },
    {
      "term": "APLASTIC ANAEMIA",
      "count": 110
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 110
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 107
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 105
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 105
    },
    {
      "term": "BACK PAIN",
      "count": 103
    },
    {
      "term": "CELLULITIS",
      "count": 103
    },
    {
      "term": "CONSTIPATION",
      "count": 103
    },
    {
      "term": "RASH",
      "count": 100
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 98
    },
    {
      "term": "SECONDARY IMMUNODEFICIENCY",
      "count": 97
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 96
    },
    {
      "term": "MALAISE",
      "count": 95
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 92
    },
    {
      "term": "DEHYDRATION",
      "count": 92
    },
    {
      "term": "HAEMATURIA",
      "count": 91
    },
    {
      "term": "CYTOMEGALOVIRUS VIRAEMIA",
      "count": 90
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 89
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 88
    },
    {
      "term": "PNEUMONITIS",
      "count": 88
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 86
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 82
    },
    {
      "term": "COUGH",
      "count": 81
    },
    {
      "term": "CYTOPENIA",
      "count": 80
    },
    {
      "term": "CARDIAC ARREST",
      "count": 79
    },
    {
      "term": "HYPOXIA",
      "count": 79
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 79
    },
    {
      "term": "DIZZINESS",
      "count": 78
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 77
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 77
    },
    {
      "term": "BACTERAEMIA",
      "count": 76
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 75
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 75
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 75
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 75
    },
    {
      "term": "SOMNOLENCE",
      "count": 73
    },
    {
      "term": "ALOPECIA",
      "count": 69
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 69
    },
    {
      "term": "EPISTAXIS",
      "count": 69
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 69
    },
    {
      "term": "VENOOCCLUSIVE DISEASE",
      "count": 69
    },
    {
      "term": "MENTAL STATUS CHANGES",
      "count": 67
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 66
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 66
    },
    {
      "term": "COLITIS",
      "count": 64
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 64
    }
  ]
}