{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 6351
    },
    {
      "term": "COLITIS ULCERATIVE",
      "count": 4457
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 4420
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 3332
    },
    {
      "term": "DIARRHOEA",
      "count": 2612
    },
    {
      "term": "HAEMATOCHEZIA",
      "count": 2416
    },
    {
      "term": "FATIGUE",
      "count": 2167
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 2155
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1860
    },
    {
      "term": "NAUSEA",
      "count": 1826
    },
    {
      "term": "HEADACHE",
      "count": 1824
    },
    {
      "term": "FREQUENT BOWEL MOVEMENTS",
      "count": 1758
    },
    {
      "term": "PYREXIA",
      "count": 1745
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 1609
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 1576
    },
    {
      "term": "ARTHRALGIA",
      "count": 1571
    },
    {
      "term": "PAIN",
      "count": 1571
    },
    {
      "term": "MALAISE",
      "count": 1533
    },
    {
      "term": "CROHN^S DISEASE",
      "count": 1322
    },
    {
      "term": "RECTAL HAEMORRHAGE",
      "count": 1272
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 1147
    },
    {
      "term": "VOMITING",
      "count": 1117
    },
    {
      "term": "DIZZINESS",
      "count": 1001
    },
    {
      "term": "DYSPNOEA",
      "count": 996
    },
    {
      "term": "RASH",
      "count": 991
    },
    {
      "term": "ASTHENIA",
      "count": 984
    },
    {
      "term": "COVID-19",
      "count": 979
    },
    {
      "term": "PNEUMONIA",
      "count": 948
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 914
    },
    {
      "term": "HYPERTENSION",
      "count": 847
    },
    {
      "term": "COLITIS",
      "count": 841
    },
    {
      "term": "PRURITUS",
      "count": 824
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 796
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 765
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 759
    },
    {
      "term": "ANXIETY",
      "count": 749
    },
    {
      "term": "DECREASED APPETITE",
      "count": 737
    },
    {
      "term": "CONSTIPATION",
      "count": 734
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 733
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 712
    },
    {
      "term": "ANAEMIA",
      "count": 707
    },
    {
      "term": "DEPRESSION",
      "count": 684
    },
    {
      "term": "ARTHRITIS",
      "count": 664
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 643
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 640
    },
    {
      "term": "STRESS",
      "count": 629
    },
    {
      "term": "COUGH",
      "count": 628
    },
    {
      "term": "MACULAR DEGENERATION",
      "count": 624
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 621
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 620
    },
    {
      "term": "DYSPEPSIA",
      "count": 608
    },
    {
      "term": "CHEST PAIN",
      "count": 598
    },
    {
      "term": "ASTHMA",
      "count": 588
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 585
    },
    {
      "term": "ALOPECIA",
      "count": 584
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 582
    },
    {
      "term": "URTICARIA",
      "count": 575
    },
    {
      "term": "INFECTION",
      "count": 574
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 554
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 546
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 545
    },
    {
      "term": "SINUSITIS",
      "count": 543
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 538
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 531
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 523
    },
    {
      "term": "MIGRAINE",
      "count": 517
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 509
    },
    {
      "term": "ERYTHEMA",
      "count": 500
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 500
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 497
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 495
    },
    {
      "term": "INSOMNIA",
      "count": 485
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 482
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 478
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 476
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 475
    },
    {
      "term": "JOINT SWELLING",
      "count": 464
    },
    {
      "term": "HYPERCHOLESTEROLAEMIA",
      "count": 454
    },
    {
      "term": "BACK PAIN",
      "count": 453
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 441
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 436
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 432
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 431
    },
    {
      "term": "MUCOUS STOOLS",
      "count": 424
    },
    {
      "term": "PERICARDITIS",
      "count": 421
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 420
    },
    {
      "term": "WHEEZING",
      "count": 419
    },
    {
      "term": "DISCOMFORT",
      "count": 416
    },
    {
      "term": "CONTUSION",
      "count": 415
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 402
    },
    {
      "term": "FLATULENCE",
      "count": 400
    },
    {
      "term": "INFLAMMATION",
      "count": 394
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 394
    },
    {
      "term": "SOMNOLENCE",
      "count": 392
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 390
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE INFECTION",
      "count": 387
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 387
    },
    {
      "term": "PANCREATITIS",
      "count": 387
    },
    {
      "term": "PSORIASIS",
      "count": 386
    },
    {
      "term": "DEFAECATION URGENCY",
      "count": 383
    }
  ]
}