{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEPENDENCE",
      "count": 270
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 252
    },
    {
      "term": "PAIN",
      "count": 200
    },
    {
      "term": "OVERDOSE",
      "count": 196
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 187
    },
    {
      "term": "NAUSEA",
      "count": 182
    },
    {
      "term": "VOMITING",
      "count": 158
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 157
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 150
    },
    {
      "term": "FATIGUE",
      "count": 126
    },
    {
      "term": "ANXIETY",
      "count": 117
    },
    {
      "term": "INFECTION",
      "count": 114
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 110
    },
    {
      "term": "INTERNATIONAL NORMALISED RATIO FLUCTUATION",
      "count": 100
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 99
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME NEONATAL",
      "count": 98
    },
    {
      "term": "PYREXIA",
      "count": 92
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 91
    },
    {
      "term": "HYPERTENSION",
      "count": 89
    },
    {
      "term": "DEVELOPMENTAL DELAY",
      "count": 84
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 81
    },
    {
      "term": "LYME DISEASE",
      "count": 81
    },
    {
      "term": "BLOODY DISCHARGE",
      "count": 80
    },
    {
      "term": "LEARNING DISABILITY",
      "count": 76
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 75
    },
    {
      "term": "OFF LABEL USE",
      "count": 74
    },
    {
      "term": "DIZZINESS",
      "count": 73
    },
    {
      "term": "RASH",
      "count": 71
    },
    {
      "term": "DEATH",
      "count": 66
    },
    {
      "term": "MALAISE",
      "count": 66
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 65
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 62
    },
    {
      "term": "HEADACHE",
      "count": 61
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 61
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 59
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 59
    },
    {
      "term": "PSORIASIS",
      "count": 58
    },
    {
      "term": "DRUG INTERACTION",
      "count": 57
    },
    {
      "term": "JOINT SWELLING",
      "count": 57
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 56
    },
    {
      "term": "IRON DEFICIENCY",
      "count": 51
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 51
    },
    {
      "term": "PLATELET COUNT INCREASED",
      "count": 50
    },
    {
      "term": "RED BLOOD CELL SEDIMENTATION RATE INCREASED",
      "count": 49
    },
    {
      "term": "SECRETION DISCHARGE",
      "count": 48
    },
    {
      "term": "HYPOTENSION",
      "count": 46
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 46
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 44
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 44
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 44
    },
    {
      "term": "HERPES ZOSTER",
      "count": 40
    },
    {
      "term": "DIARRHOEA",
      "count": 39
    },
    {
      "term": "DYSPNOEA",
      "count": 39
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 36
    },
    {
      "term": "BACK PAIN",
      "count": 36
    },
    {
      "term": "CONSTIPATION",
      "count": 36
    },
    {
      "term": "CONTRAST MEDIA ALLERGY",
      "count": 36
    },
    {
      "term": "DEPRESSION",
      "count": 35
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 35
    },
    {
      "term": "BRONCHITIS CHRONIC",
      "count": 33
    },
    {
      "term": "OBLITERATIVE BRONCHIOLITIS",
      "count": 31
    },
    {
      "term": "ERYTHEMA",
      "count": 30
    },
    {
      "term": "LEUKOPENIA",
      "count": 29
    },
    {
      "term": "ASTHMA",
      "count": 28
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 25
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 25
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 25
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 24
    },
    {
      "term": "URTICARIA",
      "count": 24
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 23
    },
    {
      "term": "DISABILITY",
      "count": 23
    },
    {
      "term": "FLUID RETENTION",
      "count": 23
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 23
    },
    {
      "term": "IMMUNODEFICIENCY",
      "count": 23
    },
    {
      "term": "NERVOUS SYSTEM DISORDER",
      "count": 23
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 22
    },
    {
      "term": "RASH ERYTHEMATOUS",
      "count": 22
    },
    {
      "term": "SKIN REACTION",
      "count": 22
    },
    {
      "term": "BURSITIS",
      "count": 21
    },
    {
      "term": "COELIAC DISEASE",
      "count": 21
    },
    {
      "term": "FALL",
      "count": 21
    },
    {
      "term": "PRESCRIBED OVERDOSE",
      "count": 21
    },
    {
      "term": "PRURITUS",
      "count": 21
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 20
    },
    {
      "term": "ANAEMIA",
      "count": 19
    },
    {
      "term": "PNEUMONIA",
      "count": 19
    },
    {
      "term": "TEMPERATURE REGULATION DISORDER",
      "count": 19
    },
    {
      "term": "VISION ABNORMAL NEONATAL",
      "count": 19
    },
    {
      "term": "FOOD ALLERGY",
      "count": 18
    },
    {
      "term": "HALLUCINATION",
      "count": 18
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 16
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 16
    },
    {
      "term": "BLOOD POTASSIUM INCREASED",
      "count": 16
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 16
    },
    {
      "term": "CHEST PAIN",
      "count": 15
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 15
    },
    {
      "term": "RENAL FAILURE",
      "count": 15
    },
    {
      "term": "TOXIC ENCEPHALOPATHY",
      "count": 15
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 15
    },
    {
      "term": "ALOPECIA",
      "count": 14
    }
  ]
}