{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "VIROLOGIC FAILURE",
      "count": 137
    },
    {
      "term": "VIRAL MUTATION IDENTIFIED",
      "count": 125
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 123
    },
    {
      "term": "DRUG INTERACTION",
      "count": 80
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 77
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 73
    },
    {
      "term": "OFF LABEL USE",
      "count": 63
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 62
    },
    {
      "term": "TREATMENT NONCOMPLIANCE",
      "count": 56
    },
    {
      "term": "NAUSEA",
      "count": 53
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 50
    },
    {
      "term": "PYREXIA",
      "count": 46
    },
    {
      "term": "DEATH",
      "count": 43
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 43
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 36
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 36
    },
    {
      "term": "ANAEMIA",
      "count": 35
    },
    {
      "term": "PNEUMONIA",
      "count": 34
    },
    {
      "term": "PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY",
      "count": 34
    },
    {
      "term": "HEADACHE",
      "count": 33
    },
    {
      "term": "ABORTION SPONTANEOUS",
      "count": 32
    },
    {
      "term": "DIZZINESS",
      "count": 31
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME",
      "count": 31
    },
    {
      "term": "PANCYTOPENIA",
      "count": 30
    },
    {
      "term": "DEPRESSION",
      "count": 29
    },
    {
      "term": "ANXIETY",
      "count": 28
    },
    {
      "term": "DIARRHOEA",
      "count": 27
    },
    {
      "term": "VOMITING",
      "count": 27
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 26
    },
    {
      "term": "VIRAL LOAD INCREASED",
      "count": 26
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 25
    },
    {
      "term": "NEUTROPENIA",
      "count": 25
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 25
    },
    {
      "term": "ACUTE MYOCARDIAL INFARCTION",
      "count": 24
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 24
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 24
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 23
    },
    {
      "term": "BLOOD HIV RNA INCREASED",
      "count": 22
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 22
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 22
    },
    {
      "term": "HYPERTENSION",
      "count": 21
    },
    {
      "term": "RENAL FAILURE",
      "count": 20
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 20
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 19
    },
    {
      "term": "FATIGUE",
      "count": 19
    },
    {
      "term": "KAPOSI^S SARCOMA",
      "count": 19
    },
    {
      "term": "LIPODYSTROPHY ACQUIRED",
      "count": 19
    },
    {
      "term": "SEPSIS",
      "count": 19
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 19
    },
    {
      "term": "CHEST PAIN",
      "count": 18
    },
    {
      "term": "HODGKIN^S DISEASE",
      "count": 18
    },
    {
      "term": "MYALGIA",
      "count": 18
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 17
    },
    {
      "term": "HYPERLIPIDAEMIA",
      "count": 17
    },
    {
      "term": "CUSHING^S SYNDROME",
      "count": 16
    },
    {
      "term": "DYSLIPIDAEMIA",
      "count": 16
    },
    {
      "term": "DYSPNOEA",
      "count": 16
    },
    {
      "term": "GAMMA-GLUTAMYLTRANSFERASE INCREASED",
      "count": 16
    },
    {
      "term": "LIVE BIRTH",
      "count": 16
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 16
    },
    {
      "term": "ASTHENIA",
      "count": 15
    },
    {
      "term": "CSF HIV ESCAPE SYNDROME",
      "count": 15
    },
    {
      "term": "FALL",
      "count": 15
    },
    {
      "term": "MALAISE",
      "count": 15
    },
    {
      "term": "MULTIPLE-DRUG RESISTANCE",
      "count": 15
    },
    {
      "term": "NEPHROLITHIASIS",
      "count": 15
    },
    {
      "term": "PARAESTHESIA",
      "count": 15
    },
    {
      "term": "RASH",
      "count": 15
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 15
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 14
    },
    {
      "term": "COVID-19",
      "count": 14
    },
    {
      "term": "DYSURIA",
      "count": 14
    },
    {
      "term": "HIV INFECTION",
      "count": 14
    },
    {
      "term": "HODGKIN'S DISEASE",
      "count": 14
    },
    {
      "term": "HYPERBILIRUBINAEMIA",
      "count": 14
    },
    {
      "term": "PAIN",
      "count": 14
    },
    {
      "term": "SQUAMOUS CELL CARCINOMA",
      "count": 14
    },
    {
      "term": "BACK PAIN",
      "count": 13
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 13
    },
    {
      "term": "INSOMNIA",
      "count": 13
    },
    {
      "term": "LYMPHOMA",
      "count": 13
    },
    {
      "term": "ORAL CANDIDIASIS",
      "count": 13
    },
    {
      "term": "PANCREATITIS",
      "count": 13
    },
    {
      "term": "SKIN LESION",
      "count": 13
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 13
    },
    {
      "term": "BRAIN OEDEMA",
      "count": 12
    },
    {
      "term": "CELLULITIS",
      "count": 12
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 12
    },
    {
      "term": "HYPOXIA",
      "count": 12
    },
    {
      "term": "IMMUNE RECONSTITUTION SYNDROME",
      "count": 12
    },
    {
      "term": "IMMUNODEFICIENCY",
      "count": 12
    },
    {
      "term": "LABORATORY TEST ABNORMAL",
      "count": 12
    },
    {
      "term": "LUNG NEOPLASM MALIGNANT",
      "count": 12
    },
    {
      "term": "LYMPHOEDEMA",
      "count": 12
    },
    {
      "term": "NERVOUS SYSTEM DISORDER",
      "count": 12
    },
    {
      "term": "OSTEOPOROSIS",
      "count": 12
    },
    {
      "term": "PSYCHIATRIC SYMPTOM",
      "count": 12
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 12
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 11
    },
    {
      "term": "BACTERAEMIA",
      "count": 11
    }
  ]
}