{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "PAIN",
      "count": 651
    },
    {
      "term": "RENAL FAILURE",
      "count": 621
    },
    {
      "term": "ANXIETY",
      "count": 513
    },
    {
      "term": "INJURY",
      "count": 495
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 490
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 482
    },
    {
      "term": "UNEVALUABLE EVENT",
      "count": 470
    },
    {
      "term": "DEATH",
      "count": 463
    },
    {
      "term": "STRESS",
      "count": 451
    },
    {
      "term": "FEAR",
      "count": 430
    },
    {
      "term": "RENAL INJURY",
      "count": 394
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 388
    },
    {
      "term": "NAUSEA",
      "count": 377
    },
    {
      "term": "OFF LABEL USE",
      "count": 371
    },
    {
      "term": "VOMITING",
      "count": 333
    },
    {
      "term": "ANHEDONIA",
      "count": 313
    },
    {
      "term": "DYSPNOEA",
      "count": 297
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 293
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 281
    },
    {
      "term": "ANAEMIA",
      "count": 257
    },
    {
      "term": "SEPSIS",
      "count": 254
    },
    {
      "term": "PYREXIA",
      "count": 245
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 238
    },
    {
      "term": "HEADACHE",
      "count": 206
    },
    {
      "term": "CONSTIPATION",
      "count": 205
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 200
    },
    {
      "term": "DEPRESSION",
      "count": 199
    },
    {
      "term": "RASH",
      "count": 198
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 192
    },
    {
      "term": "PRURITUS",
      "count": 191
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 190
    },
    {
      "term": "SOMNOLENCE",
      "count": 189
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 181
    },
    {
      "term": "FATIGUE",
      "count": 180
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 177
    },
    {
      "term": "PNEUMONIA",
      "count": 174
    },
    {
      "term": "DIARRHOEA",
      "count": 172
    },
    {
      "term": "HYPOTENSION",
      "count": 172
    },
    {
      "term": "ASTHENIA",
      "count": 167
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 161
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 147
    },
    {
      "term": "CARDIOGENIC SHOCK",
      "count": 146
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 145
    },
    {
      "term": "ASCITES",
      "count": 142
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 142
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 134
    },
    {
      "term": "VENTRICULAR FIBRILLATION",
      "count": 134
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 131
    },
    {
      "term": "CHILLS",
      "count": 130
    },
    {
      "term": "HYPERTENSION",
      "count": 128
    },
    {
      "term": "DIZZINESS",
      "count": 124
    },
    {
      "term": "APPENDICITIS",
      "count": 123
    },
    {
      "term": "SWELLING",
      "count": 122
    },
    {
      "term": "THROMBOSIS",
      "count": 122
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 121
    },
    {
      "term": "APPENDICOLITH",
      "count": 120
    },
    {
      "term": "BRAIN OEDEMA",
      "count": 119
    },
    {
      "term": "DRY MOUTH",
      "count": 119
    },
    {
      "term": "HYPOPHOSPHATAEMIA",
      "count": 118
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 117
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 112
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 111
    },
    {
      "term": "MYASTHENIA GRAVIS",
      "count": 110
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 108
    },
    {
      "term": "BLOOD PHOSPHORUS INCREASED",
      "count": 107
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 106
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 105
    },
    {
      "term": "NEURALGIA",
      "count": 105
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 104
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 103
    },
    {
      "term": "CARDIAC ARREST",
      "count": 102
    },
    {
      "term": "HYPERPHOSPHATAEMIA",
      "count": 102
    },
    {
      "term": "INCORRECT ROUTE OF PRODUCT ADMINISTRATION",
      "count": 102
    },
    {
      "term": "CHRONIC OBSTRUCTIVE PULMONARY DISEASE",
      "count": 100
    },
    {
      "term": "ERYTHEMA",
      "count": 99
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 99
    },
    {
      "term": "SLEEP DISORDER",
      "count": 98
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 97
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 97
    },
    {
      "term": "DRUG INTERACTION",
      "count": 95
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 92
    },
    {
      "term": "BLOOD URIC ACID INCREASED",
      "count": 91
    },
    {
      "term": "TREMOR",
      "count": 89
    },
    {
      "term": "COUGH",
      "count": 87
    },
    {
      "term": "MALAISE",
      "count": 87
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 85
    },
    {
      "term": "NEUTROPENIA",
      "count": 85
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 82
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 81
    },
    {
      "term": "BLOOD UREA INCREASED",
      "count": 80
    },
    {
      "term": "COMA",
      "count": 80
    },
    {
      "term": "DEHYDRATION",
      "count": 76
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 75
    },
    {
      "term": "DECREASED APPETITE",
      "count": 75
    },
    {
      "term": "END STAGE RENAL DISEASE",
      "count": 75
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 75
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 74
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 71
    },
    {
      "term": "ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED",
      "count": 70
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 69
    }
  ]
}