{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DIARRHOEA",
      "count": 1882
    },
    {
      "term": "NAUSEA",
      "count": 1484
    },
    {
      "term": "VOMITING",
      "count": 1207
    },
    {
      "term": "NEUTROPENIA",
      "count": 1170
    },
    {
      "term": "PYREXIA",
      "count": 1040
    },
    {
      "term": "OFF LABEL USE",
      "count": 1002
    },
    {
      "term": "FATIGUE",
      "count": 975
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 818
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 753
    },
    {
      "term": "DYSPNOEA",
      "count": 749
    },
    {
      "term": "ASTHENIA",
      "count": 702
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 695
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 667
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 666
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 664
    },
    {
      "term": "ANAEMIA",
      "count": 611
    },
    {
      "term": "DEHYDRATION",
      "count": 611
    },
    {
      "term": "SEPSIS",
      "count": 533
    },
    {
      "term": "PAIN",
      "count": 512
    },
    {
      "term": "RASH",
      "count": 490
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 481
    },
    {
      "term": "ARTHRALGIA",
      "count": 480
    },
    {
      "term": "HYPERTENSION",
      "count": 472
    },
    {
      "term": "PNEUMONIA",
      "count": 471
    },
    {
      "term": "DEATH",
      "count": 467
    },
    {
      "term": "HEADACHE",
      "count": 452
    },
    {
      "term": "HYPOTENSION",
      "count": 452
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 446
    },
    {
      "term": "DECREASED APPETITE",
      "count": 428
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 414
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 407
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 394
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 391
    },
    {
      "term": "MALAISE",
      "count": 364
    },
    {
      "term": "LEUKOPENIA",
      "count": 341
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 340
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 337
    },
    {
      "term": "DIZZINESS",
      "count": 333
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 330
    },
    {
      "term": "STOMATITIS",
      "count": 330
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 320
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 318
    },
    {
      "term": "COUGH",
      "count": 310
    },
    {
      "term": "CHILLS",
      "count": 308
    },
    {
      "term": "INFECTION",
      "count": 305
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 296
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 296
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 296
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 292
    },
    {
      "term": "CHEST PAIN",
      "count": 288
    },
    {
      "term": "FALL",
      "count": 280
    },
    {
      "term": "TACHYCARDIA",
      "count": 279
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 275
    },
    {
      "term": "BACK PAIN",
      "count": 269
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 269
    },
    {
      "term": "RENAL FAILURE",
      "count": 254
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 247
    },
    {
      "term": "PARAESTHESIA",
      "count": 247
    },
    {
      "term": "PRURITUS",
      "count": 247
    },
    {
      "term": "PANCYTOPENIA",
      "count": 245
    },
    {
      "term": "CONSTIPATION",
      "count": 244
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 242
    },
    {
      "term": "ERYTHEMA",
      "count": 236
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 227
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 219
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 218
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 218
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 216
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 215
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 214
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 213
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 212
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 210
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 208
    },
    {
      "term": "NEUROTOXICITY",
      "count": 206
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 204
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 194
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 193
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 191
    },
    {
      "term": "COLORECTAL CANCER METASTATIC",
      "count": 191
    },
    {
      "term": "DRUG TOXICITY",
      "count": 189
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 188
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 187
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 185
    },
    {
      "term": "ASCITES",
      "count": 183
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 183
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 182
    },
    {
      "term": "DRUG INTERACTION",
      "count": 180
    },
    {
      "term": "COLITIS",
      "count": 178
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 176
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 174
    },
    {
      "term": "JOINT SWELLING",
      "count": 172
    },
    {
      "term": "ALOPECIA",
      "count": 171
    },
    {
      "term": "COVID-19",
      "count": 170
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 169
    },
    {
      "term": "DYSPHAGIA",
      "count": 168
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 166
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 161
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 160
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 158
    }
  ]
}