{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "FATIGUE",
      "count": 6012
    },
    {
      "term": "NEUTROPENIA",
      "count": 4436
    },
    {
      "term": "NAUSEA",
      "count": 4369
    },
    {
      "term": "DIARRHOEA",
      "count": 3830
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 3630
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 3223
    },
    {
      "term": "ARTHRALGIA",
      "count": 2986
    },
    {
      "term": "ALOPECIA",
      "count": 2829
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 2517
    },
    {
      "term": "DYSPNOEA",
      "count": 2322
    },
    {
      "term": "ASTHENIA",
      "count": 2318
    },
    {
      "term": "PAIN",
      "count": 2193
    },
    {
      "term": "VOMITING",
      "count": 2152
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1945
    },
    {
      "term": "HEADACHE",
      "count": 1886
    },
    {
      "term": "OFF LABEL USE",
      "count": 1884
    },
    {
      "term": "DEATH",
      "count": 1862
    },
    {
      "term": "METASTASES TO BONE",
      "count": 1816
    },
    {
      "term": "ANAEMIA",
      "count": 1781
    },
    {
      "term": "DIZZINESS",
      "count": 1737
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 1711
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 1679
    },
    {
      "term": "MALAISE",
      "count": 1667
    },
    {
      "term": "COUGH",
      "count": 1559
    },
    {
      "term": "PYREXIA",
      "count": 1550
    },
    {
      "term": "BREAST CANCER",
      "count": 1458
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1421
    },
    {
      "term": "PRURITUS",
      "count": 1377
    },
    {
      "term": "CONSTIPATION",
      "count": 1350
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 1325
    },
    {
      "term": "RASH",
      "count": 1287
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1280
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 1279
    },
    {
      "term": "BACK PAIN",
      "count": 1268
    },
    {
      "term": "LEUKOPENIA",
      "count": 1259
    },
    {
      "term": "HOT FLUSH",
      "count": 1254
    },
    {
      "term": "INSOMNIA",
      "count": 1095
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 1077
    },
    {
      "term": "FALL",
      "count": 1066
    },
    {
      "term": "BONE PAIN",
      "count": 1046
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 1039
    },
    {
      "term": "MYALGIA",
      "count": 1037
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1022
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 948
    },
    {
      "term": "PNEUMONIA",
      "count": 942
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 923
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 923
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 864
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 852
    },
    {
      "term": "STOMATITIS",
      "count": 834
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 829
    },
    {
      "term": "ANXIETY",
      "count": 783
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 758
    },
    {
      "term": "COVID-19",
      "count": 735
    },
    {
      "term": "DEPRESSION",
      "count": 722
    },
    {
      "term": "DRY SKIN",
      "count": 710
    },
    {
      "term": "HYPERTENSION",
      "count": 697
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 691
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 677
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 675
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 669
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 653
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 641
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 639
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 638
    },
    {
      "term": "ASCITES",
      "count": 637
    },
    {
      "term": "RED BLOOD CELL COUNT DECREASED",
      "count": 637
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 630
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 623
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 611
    },
    {
      "term": "SOMNOLENCE",
      "count": 610
    },
    {
      "term": "CHILLS",
      "count": 609
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 602
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 600
    },
    {
      "term": "PARAESTHESIA",
      "count": 583
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 572
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 558
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 557
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 552
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 548
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 527
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 526
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 524
    },
    {
      "term": "DYSPEPSIA",
      "count": 521
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 514
    },
    {
      "term": "VISION BLURRED",
      "count": 513
    },
    {
      "term": "SEPSIS",
      "count": 511
    },
    {
      "term": "EPISTAXIS",
      "count": 510
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 510
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 509
    },
    {
      "term": "CHEST PAIN",
      "count": 497
    },
    {
      "term": "DEHYDRATION",
      "count": 472
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 470
    },
    {
      "term": "TACHYCARDIA",
      "count": 461
    },
    {
      "term": "SYNCOPE",
      "count": 459
    },
    {
      "term": "FULL BLOOD COUNT DECREASED",
      "count": 451
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 440
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 439
    },
    {
      "term": "ERYTHEMA",
      "count": 432
    },
    {
      "term": "ILLNESS",
      "count": 429
    }
  ]
}