{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 356
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 177
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 150
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 111
    },
    {
      "term": "DRUG INTERACTION",
      "count": 111
    },
    {
      "term": "PANCYTOPENIA",
      "count": 92
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 87
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 79
    },
    {
      "term": "CYTOMEGALOVIRUS VIRAEMIA",
      "count": 74
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 65
    },
    {
      "term": "CYSTITIS HAEMORRHAGIC",
      "count": 59
    },
    {
      "term": "NEUTROPENIA",
      "count": 58
    },
    {
      "term": "BK VIRUS INFECTION",
      "count": 57
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 56
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 55
    },
    {
      "term": "PYREXIA",
      "count": 55
    },
    {
      "term": "ENCEPHALITIS CYTOMEGALOVIRUS",
      "count": 51
    },
    {
      "term": "LEUKOPENIA",
      "count": 50
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 50
    },
    {
      "term": "POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER",
      "count": 50
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 48
    },
    {
      "term": "DIARRHOEA",
      "count": 46
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 45
    },
    {
      "term": "EPSTEIN-BARR VIRAEMIA",
      "count": 42
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 42
    },
    {
      "term": "GENERALISED OEDEMA",
      "count": 42
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 37
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 35
    },
    {
      "term": "LUNG DISORDER",
      "count": 35
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 32
    },
    {
      "term": "DEATH",
      "count": 31
    },
    {
      "term": "SEPSIS",
      "count": 31
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 31
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 30
    },
    {
      "term": "OESOPHAGITIS",
      "count": 30
    },
    {
      "term": "THROMBOTIC MICROANGIOPATHY",
      "count": 30
    },
    {
      "term": "ANAEMIA",
      "count": 28
    },
    {
      "term": "COVID-19",
      "count": 28
    },
    {
      "term": "NAUSEA",
      "count": 28
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 28
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 27
    },
    {
      "term": "PNEUMONIA",
      "count": 26
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE",
      "count": 25
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 25
    },
    {
      "term": "CYTOMEGALOVIRUS TEST POSITIVE",
      "count": 24
    },
    {
      "term": "CYTOMEGALOVIRUS COLITIS",
      "count": 23
    },
    {
      "term": "IMMUNOSUPPRESSANT DRUG LEVEL INCREASED",
      "count": 23
    },
    {
      "term": "DYSPNOEA",
      "count": 22
    },
    {
      "term": "RENAL FAILURE",
      "count": 22
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 21
    },
    {
      "term": "EPSTEIN-BARR VIRUS INFECTION REACTIVATION",
      "count": 20
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 20
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE IN GASTROINTESTINAL TRACT",
      "count": 19
    },
    {
      "term": "INFECTION",
      "count": 19
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 18
    },
    {
      "term": "FATIGUE",
      "count": 18
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 18
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 17
    },
    {
      "term": "VIRAL LOAD INCREASED",
      "count": 17
    },
    {
      "term": "ADENOVIRUS INFECTION",
      "count": 16
    },
    {
      "term": "ALTERED STATE OF CONSCIOUSNESS",
      "count": 16
    },
    {
      "term": "APLASTIC ANAEMIA",
      "count": 16
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 16
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 16
    },
    {
      "term": "POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME",
      "count": 16
    },
    {
      "term": "ACUTE RESPIRATORY FAILURE",
      "count": 15
    },
    {
      "term": "BACTERAEMIA",
      "count": 15
    },
    {
      "term": "SINUSITIS",
      "count": 15
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 15
    },
    {
      "term": "CYSTITIS VIRAL",
      "count": 14
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 14
    },
    {
      "term": "KLEBSIELLA INFECTION",
      "count": 14
    },
    {
      "term": "STAPHYLOCOCCAL SEPSIS",
      "count": 14
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 14
    },
    {
      "term": "BACTERIAL SEPSIS",
      "count": 13
    },
    {
      "term": "COLITIS",
      "count": 13
    },
    {
      "term": "DRUG LEVEL DECREASED",
      "count": 13
    },
    {
      "term": "DYSURIA",
      "count": 13
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 13
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 13
    },
    {
      "term": "VOMITING",
      "count": 13
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 12
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 12
    },
    {
      "term": "DECREASED APPETITE",
      "count": 12
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 12
    },
    {
      "term": "GINGIVITIS ULCERATIVE",
      "count": 12
    },
    {
      "term": "HYPOTENSION",
      "count": 12
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 12
    },
    {
      "term": "LACTIC ACIDOSIS",
      "count": 12
    },
    {
      "term": "LYMPHOPENIA",
      "count": 12
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 12
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 12
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 12
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 12
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 11
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 11
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 11
    },
    {
      "term": "CARDIAC FAILURE ACUTE",
      "count": 11
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 11
    },
    {
      "term": "STATUS EPILEPTICUS",
      "count": 11
    }
  ]
}