{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 25044
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 17017
    },
    {
      "term": "PAIN",
      "count": 13463
    },
    {
      "term": "ARTHRALGIA",
      "count": 12090
    },
    {
      "term": "JOINT SWELLING",
      "count": 12037
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 11900
    },
    {
      "term": "FATIGUE",
      "count": 10859
    },
    {
      "term": "RASH",
      "count": 10327
    },
    {
      "term": "OFF LABEL USE",
      "count": 9532
    },
    {
      "term": "SYNOVITIS",
      "count": 8699
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 8187
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 8030
    },
    {
      "term": "ARTHROPATHY",
      "count": 7619
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 7374
    },
    {
      "term": "ALOPECIA",
      "count": 7358
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 7240
    },
    {
      "term": "SWELLING",
      "count": 7220
    },
    {
      "term": "NAUSEA",
      "count": 7200
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 7135
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 7077
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 7041
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 6587
    },
    {
      "term": "DIARRHOEA",
      "count": 6561
    },
    {
      "term": "HEADACHE",
      "count": 6518
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 6314
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 6189
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 6088
    },
    {
      "term": "HAND DEFORMITY",
      "count": 6052
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 5784
    },
    {
      "term": "PEMPHIGUS",
      "count": 5658
    },
    {
      "term": "GLOSSODYNIA",
      "count": 5637
    },
    {
      "term": "INFECTION",
      "count": 5523
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 5399
    },
    {
      "term": "WOUND",
      "count": 5311
    },
    {
      "term": "DYSPNOEA",
      "count": 5299
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 5219
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 5153
    },
    {
      "term": "MALAISE",
      "count": 5076
    },
    {
      "term": "PERICARDITIS",
      "count": 4979
    },
    {
      "term": "VOMITING",
      "count": 4969
    },
    {
      "term": "PRURITUS",
      "count": 4959
    },
    {
      "term": "HYPERTENSION",
      "count": 4831
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 4805
    },
    {
      "term": "PNEUMONIA",
      "count": 4794
    },
    {
      "term": "PYREXIA",
      "count": 4675
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 4664
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 4615
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 4558
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 4547
    },
    {
      "term": "BLISTER",
      "count": 4463
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 4422
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 4403
    },
    {
      "term": "STOMATITIS",
      "count": 4403
    },
    {
      "term": "DISCOMFORT",
      "count": 4364
    },
    {
      "term": "SINUSITIS",
      "count": 4360
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 4328
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 4264
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 4197
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 4171
    },
    {
      "term": "FOLLICULITIS",
      "count": 4165
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 3995
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 3953
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 3854
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 3791
    },
    {
      "term": "ASTHENIA",
      "count": 3622
    },
    {
      "term": "MUSCLE INJURY",
      "count": 3557
    },
    {
      "term": "URTICARIA",
      "count": 3551
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 3545
    },
    {
      "term": "INSOMNIA",
      "count": 3541
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 3434
    },
    {
      "term": "INFLAMMATION",
      "count": 3392
    },
    {
      "term": "DIZZINESS",
      "count": 3352
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 3332
    },
    {
      "term": "FIBROMYALGIA",
      "count": 3329
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 3267
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 3253
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 3235
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 3207
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 3112
    },
    {
      "term": "CONTUSION",
      "count": 3052
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 3034
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 3004
    },
    {
      "term": "INJURY",
      "count": 2822
    },
    {
      "term": "SLEEP DISORDER",
      "count": 2724
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 2682
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 2649
    },
    {
      "term": "SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE",
      "count": 2638
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 2628
    },
    {
      "term": "ARTHRITIS",
      "count": 2622
    },
    {
      "term": "DECREASED APPETITE",
      "count": 2397
    },
    {
      "term": "MUSCULOSKELETAL PAIN",
      "count": 2382
    },
    {
      "term": "LIVER INJURY",
      "count": 2370
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 2345
    },
    {
      "term": "WHEEZING",
      "count": 2342
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 2334
    },
    {
      "term": "BACK PAIN",
      "count": 2326
    },
    {
      "term": "FALL",
      "count": 2239
    },
    {
      "term": "DYSPEPSIA",
      "count": 2229
    },
    {
      "term": "GAIT INABILITY",
      "count": 2182
    },
    {
      "term": "DRY MOUTH",
      "count": 2179
    }
  ]
}