{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 254
    },
    {
      "term": "OFF LABEL USE",
      "count": 164
    },
    {
      "term": "PSORIASIS",
      "count": 162
    },
    {
      "term": "ARTHRALGIA",
      "count": 98
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 94
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 81
    },
    {
      "term": "NAUSEA",
      "count": 76
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 76
    },
    {
      "term": "PAIN",
      "count": 68
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 67
    },
    {
      "term": "EJECTION FRACTION DECREASED",
      "count": 61
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 60
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 57
    },
    {
      "term": "HEADACHE",
      "count": 55
    },
    {
      "term": "INJECTION SITE PAIN",
      "count": 54
    },
    {
      "term": "PNEUMONIA",
      "count": 54
    },
    {
      "term": "PRURITUS",
      "count": 54
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 53
    },
    {
      "term": "ARTHRITIS",
      "count": 52
    },
    {
      "term": "DIARRHOEA",
      "count": 51
    },
    {
      "term": "CELLULITIS",
      "count": 49
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 48
    },
    {
      "term": "FATIGUE",
      "count": 46
    },
    {
      "term": "HYPERTENSION",
      "count": 46
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 43
    },
    {
      "term": "ARTHROPATHY",
      "count": 42
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 42
    },
    {
      "term": "DEAFNESS",
      "count": 41
    },
    {
      "term": "INFLAMMATION",
      "count": 41
    },
    {
      "term": "PYREXIA",
      "count": 41
    },
    {
      "term": "ERYTHEMA",
      "count": 40
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 39
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 38
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 38
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 37
    },
    {
      "term": "RASH",
      "count": 36
    },
    {
      "term": "THERAPEUTIC RESPONSE DECREASED",
      "count": 35
    },
    {
      "term": "VOMITING",
      "count": 35
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 32
    },
    {
      "term": "PULMONARY FIBROSIS",
      "count": 32
    },
    {
      "term": "INJECTION SITE ERYTHEMA",
      "count": 31
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 29
    },
    {
      "term": "ALOPECIA",
      "count": 29
    },
    {
      "term": "JOINT SWELLING",
      "count": 29
    },
    {
      "term": "ADVERSE EVENT",
      "count": 28
    },
    {
      "term": "INFECTION",
      "count": 28
    },
    {
      "term": "INJECTION SITE REACTION",
      "count": 28
    },
    {
      "term": "BASAL CELL CARCINOMA",
      "count": 27
    },
    {
      "term": "DIZZINESS",
      "count": 27
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 27
    },
    {
      "term": "MALAISE",
      "count": 27
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 26
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 26
    },
    {
      "term": "SKIN ULCER",
      "count": 25
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 24
    },
    {
      "term": "INJECTION SITE SWELLING",
      "count": 24
    },
    {
      "term": "RHEUMATOID NODULE",
      "count": 24
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 23
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 23
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 22
    },
    {
      "term": "INSOMNIA",
      "count": 22
    },
    {
      "term": "UVEITIS",
      "count": 22
    },
    {
      "term": "BACK PAIN",
      "count": 21
    },
    {
      "term": "DRUG ERUPTION",
      "count": 21
    },
    {
      "term": "SYNOVITIS",
      "count": 21
    },
    {
      "term": "ANAEMIA",
      "count": 20
    },
    {
      "term": "HEPATITIS",
      "count": 20
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 20
    },
    {
      "term": "MYALGIA",
      "count": 19
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 19
    },
    {
      "term": "URTICARIA",
      "count": 19
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 18
    },
    {
      "term": "PROSTATE CANCER",
      "count": 18
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 17
    },
    {
      "term": "ENTHESOPATHY",
      "count": 17
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 17
    },
    {
      "term": "ULCER",
      "count": 17
    },
    {
      "term": "BLOOD PARATHYROID HORMONE DECREASED",
      "count": 16
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 16
    },
    {
      "term": "CHEST PAIN",
      "count": 16
    },
    {
      "term": "COVID-19",
      "count": 16
    },
    {
      "term": "HEPATIC STEATOSIS",
      "count": 16
    },
    {
      "term": "HYPERCALCAEMIA",
      "count": 16
    },
    {
      "term": "PANNICULITIS",
      "count": 16
    },
    {
      "term": "RASH PRURITIC",
      "count": 16
    },
    {
      "term": "RED BLOOD CELL SEDIMENTATION RATE INCREASED",
      "count": 16
    },
    {
      "term": "SINUSITIS",
      "count": 16
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 15
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 15
    },
    {
      "term": "FALL",
      "count": 15
    },
    {
      "term": "FLUSHING",
      "count": 15
    },
    {
      "term": "GAIT INABILITY",
      "count": 15
    },
    {
      "term": "INJECTION SITE WARMTH",
      "count": 15
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 15
    },
    {
      "term": "ACTINIC KERATOSIS",
      "count": 14
    },
    {
      "term": "ASTHENIA",
      "count": 14
    },
    {
      "term": "BREATH SOUNDS ABNORMAL",
      "count": 14
    },
    {
      "term": "DRUG TOLERANCE DECREASED",
      "count": 14
    },
    {
      "term": "DYSPNOEA",
      "count": 14
    },
    {
      "term": "FACIAL PARALYSIS",
      "count": 14
    }
  ]
}