{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 234
    },
    {
      "term": "OFF LABEL USE",
      "count": 154
    },
    {
      "term": "PYREXIA",
      "count": 113
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 88
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 85
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 80
    },
    {
      "term": "ANAEMIA",
      "count": 78
    },
    {
      "term": "VOMITING",
      "count": 75
    },
    {
      "term": "DIARRHOEA",
      "count": 73
    },
    {
      "term": "NAUSEA",
      "count": 73
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 71
    },
    {
      "term": "PNEUMONIA",
      "count": 69
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 67
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 65
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 64
    },
    {
      "term": "SEPSIS",
      "count": 63
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 56
    },
    {
      "term": "DRUG INTERACTION",
      "count": 55
    },
    {
      "term": "DYSPNOEA",
      "count": 54
    },
    {
      "term": "EPILEPSY",
      "count": 51
    },
    {
      "term": "NEUTROPENIA",
      "count": 51
    },
    {
      "term": "RASH",
      "count": 51
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 46
    },
    {
      "term": "DEATH",
      "count": 45
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 43
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 41
    },
    {
      "term": "INFECTION",
      "count": 41
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 39
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 39
    },
    {
      "term": "DECREASED APPETITE",
      "count": 37
    },
    {
      "term": "SEIZURE",
      "count": 37
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 36
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 35
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 34
    },
    {
      "term": "HYPOTENSION",
      "count": 34
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 33
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 32
    },
    {
      "term": "LEUKOPENIA",
      "count": 32
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 31
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 31
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 31
    },
    {
      "term": "KLEBSIELLA INFECTION",
      "count": 30
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 28
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 28
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 27
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 27
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 27
    },
    {
      "term": "CHILLS",
      "count": 26
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 26
    },
    {
      "term": "COUGH",
      "count": 25
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 25
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 25
    },
    {
      "term": "WHITE BLOOD CELL COUNT INCREASED",
      "count": 25
    },
    {
      "term": "ASTHENIA",
      "count": 24
    },
    {
      "term": "HYPOALBUMINAEMIA",
      "count": 24
    },
    {
      "term": "PANCYTOPENIA",
      "count": 23
    },
    {
      "term": "TOXIC SKIN ERUPTION",
      "count": 23
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 22
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 22
    },
    {
      "term": "MYCOBACTERIUM ABSCESSUS INFECTION",
      "count": 22
    },
    {
      "term": "PRURITUS",
      "count": 22
    },
    {
      "term": "ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS",
      "count": 21
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 21
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 21
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE INFECTION",
      "count": 21
    },
    {
      "term": "EOSINOPHILIA",
      "count": 21
    },
    {
      "term": "MALAISE",
      "count": 21
    },
    {
      "term": "CARDIAC ARREST",
      "count": 20
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 20
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 20
    },
    {
      "term": "BLOOD UREA INCREASED",
      "count": 19
    },
    {
      "term": "CHEST PAIN",
      "count": 19
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 19
    },
    {
      "term": "DEAFNESS NEUROSENSORY",
      "count": 19
    },
    {
      "term": "DELIRIUM",
      "count": 19
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 19
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 19
    },
    {
      "term": "ACINETOBACTER INFECTION",
      "count": 18
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 18
    },
    {
      "term": "DIZZINESS",
      "count": 18
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 18
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 18
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 17
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 17
    },
    {
      "term": "HEPATITIS CHOLESTATIC",
      "count": 17
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 17
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 17
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 16
    },
    {
      "term": "ESCHERICHIA INFECTION",
      "count": 16
    },
    {
      "term": "FATIGUE",
      "count": 16
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 16
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 16
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 16
    },
    {
      "term": "INTERNATIONAL NORMALISED RATIO INCREASED",
      "count": 16
    },
    {
      "term": "LIVER INJURY",
      "count": 16
    },
    {
      "term": "NOCARDIOSIS",
      "count": 16
    },
    {
      "term": "PSEUDOMONAS INFECTION",
      "count": 16
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 16
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 15
    },
    {
      "term": "HYPERTENSION",
      "count": 15
    }
  ]
}