{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEATH",
      "count": 515
    },
    {
      "term": "NAUSEA",
      "count": 313
    },
    {
      "term": "DIARRHOEA",
      "count": 274
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 221
    },
    {
      "term": "FATIGUE",
      "count": 208
    },
    {
      "term": "VOMITING",
      "count": 189
    },
    {
      "term": "DYSPNOEA",
      "count": 156
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 143
    },
    {
      "term": "NEOPLASM MALIGNANT",
      "count": 142
    },
    {
      "term": "PYREXIA",
      "count": 137
    },
    {
      "term": "ASTHENIA",
      "count": 131
    },
    {
      "term": "OFF LABEL USE",
      "count": 130
    },
    {
      "term": "FALL",
      "count": 126
    },
    {
      "term": "PRURITUS",
      "count": 121
    },
    {
      "term": "DIZZINESS",
      "count": 119
    },
    {
      "term": "ARTHRALGIA",
      "count": 115
    },
    {
      "term": "SEPSIS",
      "count": 112
    },
    {
      "term": "HEADACHE",
      "count": 110
    },
    {
      "term": "RASH",
      "count": 109
    },
    {
      "term": "THERAPY INTERRUPTED",
      "count": 100
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 97
    },
    {
      "term": "MALAISE",
      "count": 97
    },
    {
      "term": "DRUG INTERACTION",
      "count": 96
    },
    {
      "term": "ASCITES",
      "count": 93
    },
    {
      "term": "DECREASED APPETITE",
      "count": 93
    },
    {
      "term": "CHILLS",
      "count": 90
    },
    {
      "term": "MYALGIA",
      "count": 90
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 87
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 85
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 83
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 83
    },
    {
      "term": "ANAEMIA",
      "count": 82
    },
    {
      "term": "INSOMNIA",
      "count": 82
    },
    {
      "term": "PAIN",
      "count": 82
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 78
    },
    {
      "term": "PNEUMONIA",
      "count": 78
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 76
    },
    {
      "term": "TACHYCARDIA",
      "count": 76
    },
    {
      "term": "BLINDNESS",
      "count": 75
    },
    {
      "term": "COUGH",
      "count": 73
    },
    {
      "term": "EYE PAIN",
      "count": 73
    },
    {
      "term": "ALTERED STATE OF CONSCIOUSNESS",
      "count": 72
    },
    {
      "term": "COMA",
      "count": 72
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 72
    },
    {
      "term": "HAEMORRHAGIC STROKE",
      "count": 71
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 70
    },
    {
      "term": "HAEMATEMESIS",
      "count": 70
    },
    {
      "term": "OCULAR DISCOMFORT",
      "count": 70
    },
    {
      "term": "AMAUROSIS FUGAX",
      "count": 69
    },
    {
      "term": "HEAD DISCOMFORT",
      "count": 68
    },
    {
      "term": "PRODUCT SUBSTITUTION ISSUE",
      "count": 68
    },
    {
      "term": "CHRONIC MYELOID LEUKAEMIA",
      "count": 65
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 64
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 62
    },
    {
      "term": "SOMNOLENCE",
      "count": 62
    },
    {
      "term": "GENERALISED OEDEMA",
      "count": 61
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 61
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 60
    },
    {
      "term": "VISION BLURRED",
      "count": 59
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 57
    },
    {
      "term": "HOSPITALISATION",
      "count": 52
    },
    {
      "term": "DIPLOPIA",
      "count": 51
    },
    {
      "term": "HAEMATURIA",
      "count": 51
    },
    {
      "term": "NEUTROPENIA",
      "count": 51
    },
    {
      "term": "GASTROINTESTINAL STROMAL TUMOUR",
      "count": 50
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 50
    },
    {
      "term": "TINNITUS",
      "count": 50
    },
    {
      "term": "PANCYTOPENIA",
      "count": 48
    },
    {
      "term": "SYNCOPE",
      "count": 48
    },
    {
      "term": "PHOTOPHOBIA",
      "count": 46
    },
    {
      "term": "PRESYNCOPE",
      "count": 45
    },
    {
      "term": "THERAPY CESSATION",
      "count": 44
    },
    {
      "term": "URINARY TRACT DISORDER",
      "count": 44
    },
    {
      "term": "OEDEMA",
      "count": 43
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 42
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 42
    },
    {
      "term": "FLUID RETENTION",
      "count": 41
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 40
    },
    {
      "term": "CHEST PAIN",
      "count": 38
    },
    {
      "term": "PRODUCT PHYSICAL ISSUE",
      "count": 38
    },
    {
      "term": "CONSTIPATION",
      "count": 37
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 36
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 35
    },
    {
      "term": "INFECTION",
      "count": 35
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 35
    },
    {
      "term": "RENAL FAILURE",
      "count": 34
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 33
    },
    {
      "term": "DEHYDRATION",
      "count": 33
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 33
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 33
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 33
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 32
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 32
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 32
    },
    {
      "term": "BLAST CRISIS IN MYELOGENOUS LEUKAEMIA",
      "count": 31
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 31
    },
    {
      "term": "BACK PAIN",
      "count": 30
    },
    {
      "term": "PERIORBITAL OEDEMA",
      "count": 30
    },
    {
      "term": "SURGERY",
      "count": 30
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 29
    }
  ]
}