{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1745
    },
    {
      "term": "NAUSEA",
      "count": 1416
    },
    {
      "term": "DIARRHOEA",
      "count": 1322
    },
    {
      "term": "DEATH",
      "count": 1116
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 1101
    },
    {
      "term": "FATIGUE",
      "count": 1047
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 950
    },
    {
      "term": "VOMITING",
      "count": 907
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 899
    },
    {
      "term": "OFF LABEL USE",
      "count": 805
    },
    {
      "term": "DYSPNOEA",
      "count": 747
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 716
    },
    {
      "term": "RASH",
      "count": 675
    },
    {
      "term": "PYREXIA",
      "count": 615
    },
    {
      "term": "HEADACHE",
      "count": 607
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 604
    },
    {
      "term": "ANAEMIA",
      "count": 588
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 585
    },
    {
      "term": "ASTHENIA",
      "count": 578
    },
    {
      "term": "ARTHRALGIA",
      "count": 577
    },
    {
      "term": "CHRONIC MYELOID LEUKAEMIA",
      "count": 548
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 543
    },
    {
      "term": "DRUG INTERACTION",
      "count": 538
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 537
    },
    {
      "term": "MYALGIA",
      "count": 523
    },
    {
      "term": "PRURITUS",
      "count": 499
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 485
    },
    {
      "term": "DIZZINESS",
      "count": 476
    },
    {
      "term": "DECREASED APPETITE",
      "count": 461
    },
    {
      "term": "MALAISE",
      "count": 459
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 450
    },
    {
      "term": "NEUTROPENIA",
      "count": 449
    },
    {
      "term": "SEPSIS",
      "count": 435
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 410
    },
    {
      "term": "GASTROINTESTINAL STROMAL TUMOUR",
      "count": 392
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 391
    },
    {
      "term": "FALL",
      "count": 373
    },
    {
      "term": "COUGH",
      "count": 361
    },
    {
      "term": "PNEUMONIA",
      "count": 350
    },
    {
      "term": "PAIN",
      "count": 338
    },
    {
      "term": "INSOMNIA",
      "count": 326
    },
    {
      "term": "THERAPEUTIC RESPONSE DECREASED",
      "count": 323
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 319
    },
    {
      "term": "ASCITES",
      "count": 318
    },
    {
      "term": "CHILLS",
      "count": 317
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 316
    },
    {
      "term": "GENERALISED OEDEMA",
      "count": 298
    },
    {
      "term": "PANCYTOPENIA",
      "count": 295
    },
    {
      "term": "TACHYCARDIA",
      "count": 286
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 284
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 283
    },
    {
      "term": "CYTOGENETIC ANALYSIS ABNORMAL",
      "count": 282
    },
    {
      "term": "SOMNOLENCE",
      "count": 282
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 277
    },
    {
      "term": "BLINDNESS",
      "count": 275
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 265
    },
    {
      "term": "OEDEMA",
      "count": 263
    },
    {
      "term": "BLAST CRISIS IN MYELOGENOUS LEUKAEMIA",
      "count": 258
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 258
    },
    {
      "term": "COMA",
      "count": 258
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 257
    },
    {
      "term": "HAEMATEMESIS",
      "count": 256
    },
    {
      "term": "FLUID RETENTION",
      "count": 251
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 248
    },
    {
      "term": "EYE PAIN",
      "count": 247
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 247
    },
    {
      "term": "HAEMORRHAGIC STROKE",
      "count": 245
    },
    {
      "term": "ALTERED STATE OF CONSCIOUSNESS",
      "count": 243
    },
    {
      "term": "VISION BLURRED",
      "count": 242
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 240
    },
    {
      "term": "OCULAR DISCOMFORT",
      "count": 235
    },
    {
      "term": "PRODUCT SUBSTITUTION ISSUE",
      "count": 235
    },
    {
      "term": "SYNCOPE",
      "count": 233
    },
    {
      "term": "PHILADELPHIA CHROMOSOME POSITIVE",
      "count": 232
    },
    {
      "term": "SECOND PRIMARY MALIGNANCY",
      "count": 231
    },
    {
      "term": "HAEMATURIA",
      "count": 230
    },
    {
      "term": "HEAD DISCOMFORT",
      "count": 230
    },
    {
      "term": "INFECTION",
      "count": 228
    },
    {
      "term": "ACUTE LYMPHOCYTIC LEUKAEMIA RECURRENT",
      "count": 226
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 225
    },
    {
      "term": "AMAUROSIS FUGAX",
      "count": 224
    },
    {
      "term": "TINNITUS",
      "count": 217
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 216
    },
    {
      "term": "NEOPLASM MALIGNANT",
      "count": 213
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 211
    },
    {
      "term": "DIPLOPIA",
      "count": 209
    },
    {
      "term": "THERAPY INTERRUPTED",
      "count": 203
    },
    {
      "term": "HOSPITALISATION",
      "count": 200
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 197
    },
    {
      "term": "PRESYNCOPE",
      "count": 197
    },
    {
      "term": "URINARY TRACT DISORDER",
      "count": 196
    },
    {
      "term": "RENAL FAILURE",
      "count": 194
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 192
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 191
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 189
    },
    {
      "term": "HYPERTENSION",
      "count": 183
    },
    {
      "term": "PERICARDIAL EFFUSION",
      "count": 181
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 181
    },
    {
      "term": "PHOTOPHOBIA",
      "count": 178
    },
    {
      "term": "THERAPY CESSATION",
      "count": 178
    }
  ]
}