{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 18261
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 13756
    },
    {
      "term": "PAIN",
      "count": 10902
    },
    {
      "term": "FATIGUE",
      "count": 9486
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 9292
    },
    {
      "term": "OFF LABEL USE",
      "count": 8592
    },
    {
      "term": "JOINT SWELLING",
      "count": 8473
    },
    {
      "term": "ARTHRALGIA",
      "count": 8470
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 8119
    },
    {
      "term": "ALOPECIA",
      "count": 7760
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 7734
    },
    {
      "term": "RASH",
      "count": 7699
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 7206
    },
    {
      "term": "ARTHROPATHY",
      "count": 7195
    },
    {
      "term": "SYNOVITIS",
      "count": 6919
    },
    {
      "term": "PEMPHIGUS",
      "count": 6633
    },
    {
      "term": "SWELLING",
      "count": 6516
    },
    {
      "term": "GLOSSODYNIA",
      "count": 6123
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 6096
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 5874
    },
    {
      "term": "HAND DEFORMITY",
      "count": 5857
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 5693
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 5445
    },
    {
      "term": "NAUSEA",
      "count": 5345
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 5289
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 5163
    },
    {
      "term": "WOUND",
      "count": 4999
    },
    {
      "term": "HEADACHE",
      "count": 4833
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 4653
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 4602
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 4551
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 4449
    },
    {
      "term": "PERICARDITIS",
      "count": 4442
    },
    {
      "term": "DIARRHOEA",
      "count": 4385
    },
    {
      "term": "DISCOMFORT",
      "count": 4359
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 4257
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 4189
    },
    {
      "term": "DYSPNOEA",
      "count": 3689
    },
    {
      "term": "INFECTION",
      "count": 3676
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 3621
    },
    {
      "term": "VOMITING",
      "count": 3553
    },
    {
      "term": "MALAISE",
      "count": 3489
    },
    {
      "term": "HYPERTENSION",
      "count": 3472
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 3450
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 3439
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 3411
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 3411
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 3240
    },
    {
      "term": "PRURITUS",
      "count": 3146
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 3127
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 3074
    },
    {
      "term": "PYREXIA",
      "count": 3050
    },
    {
      "term": "SINUSITIS",
      "count": 3016
    },
    {
      "term": "BLISTER",
      "count": 3005
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 2958
    },
    {
      "term": "PNEUMONIA",
      "count": 2943
    },
    {
      "term": "STOMATITIS",
      "count": 2916
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 2905
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 2845
    },
    {
      "term": "DIZZINESS",
      "count": 2742
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 2725
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 2711
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 2707
    },
    {
      "term": "FOLLICULITIS",
      "count": 2676
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 2631
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 2592
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 2534
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 2441
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 2435
    },
    {
      "term": "FIBROMYALGIA",
      "count": 2413
    },
    {
      "term": "MUSCLE INJURY",
      "count": 2377
    },
    {
      "term": "CONTUSION",
      "count": 2353
    },
    {
      "term": "URTICARIA",
      "count": 2329
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 2307
    },
    {
      "term": "INFLAMMATION",
      "count": 2295
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 2292
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 2231
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 2224
    },
    {
      "term": "ASTHENIA",
      "count": 2189
    },
    {
      "term": "INSOMNIA",
      "count": 2173
    },
    {
      "term": "LIVER INJURY",
      "count": 2131
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 2108
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 2061
    },
    {
      "term": "INJURY",
      "count": 2030
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 2004
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 1957
    },
    {
      "term": "SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE",
      "count": 1919
    },
    {
      "term": "MUSCULOSKELETAL PAIN",
      "count": 1888
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1834
    },
    {
      "term": "ARTHRITIS",
      "count": 1790
    },
    {
      "term": "SLEEP DISORDER",
      "count": 1742
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1739
    },
    {
      "term": "RED BLOOD CELL SEDIMENTATION RATE INCREASED",
      "count": 1730
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 1708
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 1562
    },
    {
      "term": "WHEEZING",
      "count": 1557
    },
    {
      "term": "SWOLLEN JOINT COUNT INCREASED",
      "count": 1545
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 1528
    },
    {
      "term": "FALL",
      "count": 1521
    },
    {
      "term": "DYSPEPSIA",
      "count": 1520
    }
  ]
}