{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 33131
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 21850
    },
    {
      "term": "OFF LABEL USE",
      "count": 20306
    },
    {
      "term": "PAIN",
      "count": 17595
    },
    {
      "term": "FATIGUE",
      "count": 15019
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 14552
    },
    {
      "term": "ARTHRALGIA",
      "count": 14378
    },
    {
      "term": "JOINT SWELLING",
      "count": 13376
    },
    {
      "term": "RASH",
      "count": 12072
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 11019
    },
    {
      "term": "ALOPECIA",
      "count": 10786
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 10735
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 10475
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 10360
    },
    {
      "term": "SYNOVITIS",
      "count": 10243
    },
    {
      "term": "NAUSEA",
      "count": 9952
    },
    {
      "term": "ARTHROPATHY",
      "count": 9750
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 9223
    },
    {
      "term": "SWELLING",
      "count": 9050
    },
    {
      "term": "HEADACHE",
      "count": 8866
    },
    {
      "term": "PEMPHIGUS",
      "count": 8641
    },
    {
      "term": "DIARRHOEA",
      "count": 8155
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 8040
    },
    {
      "term": "GLOSSODYNIA",
      "count": 7963
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 7878
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 7664
    },
    {
      "term": "HAND DEFORMITY",
      "count": 7562
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 7442
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 7441
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 7282
    },
    {
      "term": "VOMITING",
      "count": 6658
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 6615
    },
    {
      "term": "DYSPNOEA",
      "count": 6607
    },
    {
      "term": "WOUND",
      "count": 6529
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 6456
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 6388
    },
    {
      "term": "INFECTION",
      "count": 6205
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 6112
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 5940
    },
    {
      "term": "MALAISE",
      "count": 5905
    },
    {
      "term": "PERICARDITIS",
      "count": 5811
    },
    {
      "term": "PYREXIA",
      "count": 5665
    },
    {
      "term": "PRURITUS",
      "count": 5630
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 5608
    },
    {
      "term": "DISCOMFORT",
      "count": 5584
    },
    {
      "term": "PNEUMONIA",
      "count": 5582
    },
    {
      "term": "HYPERTENSION",
      "count": 5524
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 5493
    },
    {
      "term": "SINUSITIS",
      "count": 5046
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 4914
    },
    {
      "term": "DIZZINESS",
      "count": 4890
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 4827
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 4644
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 4617
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 4597
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 4592
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 4582
    },
    {
      "term": "ASTHENIA",
      "count": 4552
    },
    {
      "term": "STOMATITIS",
      "count": 4470
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 4440
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 4436
    },
    {
      "term": "BLISTER",
      "count": 4403
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 4297
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 4287
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 4198
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 4195
    },
    {
      "term": "URTICARIA",
      "count": 4179
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 4091
    },
    {
      "term": "INSOMNIA",
      "count": 4022
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 3964
    },
    {
      "term": "FOLLICULITIS",
      "count": 3952
    },
    {
      "term": "FIBROMYALGIA",
      "count": 3765
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 3725
    },
    {
      "term": "CONTUSION",
      "count": 3719
    },
    {
      "term": "INFLAMMATION",
      "count": 3643
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 3573
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 3568
    },
    {
      "term": "MUSCLE INJURY",
      "count": 3510
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 3455
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 3452
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 3443
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 3406
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 3368
    },
    {
      "term": "ARTHRITIS",
      "count": 3322
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 3301
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 3275
    },
    {
      "term": "FALL",
      "count": 3164
    },
    {
      "term": "LIVER INJURY",
      "count": 3042
    },
    {
      "term": "INJURY",
      "count": 3031
    },
    {
      "term": "MUSCULOSKELETAL PAIN",
      "count": 3025
    },
    {
      "term": "DECREASED APPETITE",
      "count": 3000
    },
    {
      "term": "SLEEP DISORDER",
      "count": 2910
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 2844
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 2812
    },
    {
      "term": "SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE",
      "count": 2764
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 2722
    },
    {
      "term": "DEPRESSION",
      "count": 2722
    },
    {
      "term": "RED BLOOD CELL SEDIMENTATION RATE INCREASED",
      "count": 2697
    },
    {
      "term": "COUGH",
      "count": 2685
    },
    {
      "term": "CHEST PAIN",
      "count": 2596
    }
  ]
}