{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEPENDENCE",
      "count": 268
    },
    {
      "term": "OVERDOSE",
      "count": 165
    },
    {
      "term": "DEATH",
      "count": 43
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 33
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 32
    },
    {
      "term": "DEPRESSION",
      "count": 29
    },
    {
      "term": "PAIN",
      "count": 23
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 19
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 19
    },
    {
      "term": "PRODUCT PRESCRIBING ISSUE",
      "count": 18
    },
    {
      "term": "ANXIETY",
      "count": 17
    },
    {
      "term": "NAUSEA",
      "count": 15
    },
    {
      "term": "VOMITING",
      "count": 12
    },
    {
      "term": "DRUG DIVERSION",
      "count": 10
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 10
    },
    {
      "term": "PRURITUS",
      "count": 10
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 9
    },
    {
      "term": "POST-TRAUMATIC STRESS DISORDER",
      "count": 9
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 8
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 8
    },
    {
      "term": "HALLUCINATION",
      "count": 8
    },
    {
      "term": "HEADACHE",
      "count": 8
    },
    {
      "term": "DIZZINESS",
      "count": 7
    },
    {
      "term": "DRUG ABUSE",
      "count": 7
    },
    {
      "term": "MENTAL DISORDER",
      "count": 7
    },
    {
      "term": "ARTHRALGIA",
      "count": 6
    },
    {
      "term": "FALL",
      "count": 6
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 6
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 6
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 6
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 6
    },
    {
      "term": "RENAL FAILURE",
      "count": 6
    },
    {
      "term": "ROAD TRAFFIC ACCIDENT",
      "count": 6
    },
    {
      "term": "TOOTH LOSS",
      "count": 6
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 6
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 6
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME NEONATAL",
      "count": 5
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 5
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 5
    },
    {
      "term": "INSOMNIA",
      "count": 5
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 5
    },
    {
      "term": "PNEUMONIA",
      "count": 5
    },
    {
      "term": "RASH",
      "count": 5
    },
    {
      "term": "SUBSTANCE ABUSE",
      "count": 5
    },
    {
      "term": "SUICIDAL IDEATION",
      "count": 5
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 5
    },
    {
      "term": "ASTHENIA",
      "count": 4
    },
    {
      "term": "CARDIAC ARREST",
      "count": 4
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 4
    },
    {
      "term": "CONSTIPATION",
      "count": 4
    },
    {
      "term": "DYSPEPSIA",
      "count": 4
    },
    {
      "term": "ERECTILE DYSFUNCTION",
      "count": 4
    },
    {
      "term": "FATIGUE",
      "count": 4
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 4
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 4
    },
    {
      "term": "ILLNESS",
      "count": 4
    },
    {
      "term": "INJURY",
      "count": 4
    },
    {
      "term": "MALAISE",
      "count": 4
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 4
    },
    {
      "term": "OEDEMA",
      "count": 4
    },
    {
      "term": "OSTEOPOROSIS",
      "count": 4
    },
    {
      "term": "SOMNOLENCE",
      "count": 4
    },
    {
      "term": "AGITATION",
      "count": 3
    },
    {
      "term": "AMNESIA",
      "count": 3
    },
    {
      "term": "ANGER",
      "count": 3
    },
    {
      "term": "ANXIETY DISORDER",
      "count": 3
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 3
    },
    {
      "term": "CORONARY ARTERY DISEASE",
      "count": 3
    },
    {
      "term": "DEHYDRATION",
      "count": 3
    },
    {
      "term": "FIBROMYALGIA",
      "count": 3
    },
    {
      "term": "HYPERTENSION",
      "count": 3
    },
    {
      "term": "INTENTIONAL DRUG MISUSE",
      "count": 3
    },
    {
      "term": "LEARNING DISABILITY",
      "count": 3
    },
    {
      "term": "LOSS OF LIBIDO",
      "count": 3
    },
    {
      "term": "MIGRAINE",
      "count": 3
    },
    {
      "term": "NERVOUS SYSTEM DISORDER",
      "count": 3
    },
    {
      "term": "OSTEOPENIA",
      "count": 3
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 3
    },
    {
      "term": "PRODUCT SUBSTITUTION ISSUE",
      "count": 3
    },
    {
      "term": "PSYCHOTIC DISORDER",
      "count": 3
    },
    {
      "term": "PYREXIA",
      "count": 3
    },
    {
      "term": "STRESS",
      "count": 3
    },
    {
      "term": "SUBSTANCE USE DISORDER",
      "count": 3
    },
    {
      "term": "SURGERY",
      "count": 3
    },
    {
      "term": "THINKING ABNORMAL",
      "count": 3
    },
    {
      "term": "UNEVALUABLE EVENT",
      "count": 3
    },
    {
      "term": "ABNORMAL BEHAVIOUR",
      "count": 2
    },
    {
      "term": "ACCIDENTAL OVERDOSE",
      "count": 2
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 2
    },
    {
      "term": "ADVERSE DRUG REACTION",
      "count": 2
    },
    {
      "term": "AGGRESSION",
      "count": 2
    },
    {
      "term": "ALCOHOLISM",
      "count": 2
    },
    {
      "term": "ANAEMIA",
      "count": 2
    },
    {
      "term": "ANGINA PECTORIS",
      "count": 2
    },
    {
      "term": "ANHEDONIA",
      "count": 2
    },
    {
      "term": "ARRHYTHMIA",
      "count": 2
    },
    {
      "term": "ARTHRITIS",
      "count": 2
    },
    {
      "term": "ASTHMA",
      "count": 2
    },
    {
      "term": "BIPOLAR DISORDER",
      "count": 2
    },
    {
      "term": "BONE DENSITY DECREASED",
      "count": 2
    }
  ]
}