{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 640
    },
    {
      "term": "NEUTROPENIA",
      "count": 464
    },
    {
      "term": "FATIGUE",
      "count": 449
    },
    {
      "term": "METASTASES TO BONE",
      "count": 363
    },
    {
      "term": "DEATH",
      "count": 326
    },
    {
      "term": "DIARRHOEA",
      "count": 297
    },
    {
      "term": "NAUSEA",
      "count": 288
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 280
    },
    {
      "term": "ASTHENIA",
      "count": 279
    },
    {
      "term": "OFF LABEL USE",
      "count": 250
    },
    {
      "term": "ANAEMIA",
      "count": 219
    },
    {
      "term": "PAIN",
      "count": 200
    },
    {
      "term": "DYSPNOEA",
      "count": 197
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 185
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 180
    },
    {
      "term": "ARTHRALGIA",
      "count": 175
    },
    {
      "term": "HEADACHE",
      "count": 172
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 167
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 159
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 158
    },
    {
      "term": "DECREASED APPETITE",
      "count": 154
    },
    {
      "term": "HOT FLUSH",
      "count": 152
    },
    {
      "term": "PYREXIA",
      "count": 146
    },
    {
      "term": "PNEUMONIA",
      "count": 140
    },
    {
      "term": "MALAISE",
      "count": 136
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 135
    },
    {
      "term": "VOMITING",
      "count": 133
    },
    {
      "term": "CONSTIPATION",
      "count": 131
    },
    {
      "term": "BREAST CANCER",
      "count": 125
    },
    {
      "term": "DIZZINESS",
      "count": 125
    },
    {
      "term": "PROSTATIC SPECIFIC ANTIGEN INCREASED",
      "count": 125
    },
    {
      "term": "RASH",
      "count": 124
    },
    {
      "term": "HYPERTENSION",
      "count": 121
    },
    {
      "term": "PROSTATE CANCER",
      "count": 114
    },
    {
      "term": "BACK PAIN",
      "count": 111
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 111
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 111
    },
    {
      "term": "ALOPECIA",
      "count": 107
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 105
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 102
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 101
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 101
    },
    {
      "term": "FALL",
      "count": 100
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 100
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 98
    },
    {
      "term": "LEUKOPENIA",
      "count": 97
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 95
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 93
    },
    {
      "term": "INSOMNIA",
      "count": 91
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 91
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 89
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 89
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 88
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 86
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 84
    },
    {
      "term": "HAEMATURIA",
      "count": 82
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 82
    },
    {
      "term": "BONE PAIN",
      "count": 81
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 75
    },
    {
      "term": "ANXIETY",
      "count": 74
    },
    {
      "term": "MYALGIA",
      "count": 74
    },
    {
      "term": "PRURITUS",
      "count": 74
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 73
    },
    {
      "term": "DRUG INTERACTION",
      "count": 72
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 71
    },
    {
      "term": "COUGH",
      "count": 70
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 69
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 68
    },
    {
      "term": "HAEMORRHAGE",
      "count": 67
    },
    {
      "term": "SYNCOPE",
      "count": 65
    },
    {
      "term": "METASTASES TO CENTRAL NERVOUS SYSTEM",
      "count": 63
    },
    {
      "term": "DECREASED IMMUNE RESPONSIVENESS",
      "count": 59
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 59
    },
    {
      "term": "ASCITES",
      "count": 58
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 58
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 58
    },
    {
      "term": "LYMPHOPENIA",
      "count": 58
    },
    {
      "term": "PNEUMONITIS",
      "count": 58
    },
    {
      "term": "PRODUCTIVE COUGH",
      "count": 57
    },
    {
      "term": "VIRAL INFECTION",
      "count": 57
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 56
    },
    {
      "term": "LACRIMATION INCREASED",
      "count": 56
    },
    {
      "term": "RENAL DISORDER",
      "count": 56
    },
    {
      "term": "CHEST PAIN",
      "count": 55
    },
    {
      "term": "EOSINOPHILIC PNEUMONIA",
      "count": 55
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 55
    },
    {
      "term": "ASTHMA",
      "count": 54
    },
    {
      "term": "ERYTHEMA",
      "count": 54
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 54
    },
    {
      "term": "METASTASES TO SPINE",
      "count": 54
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 53
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 52
    },
    {
      "term": "OBESITY",
      "count": 52
    },
    {
      "term": "RESPIRATORY TRACT INFECTION",
      "count": 52
    },
    {
      "term": "DEPRESSION",
      "count": 51
    },
    {
      "term": "DRY SKIN",
      "count": 51
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 50
    },
    {
      "term": "COVID-19",
      "count": 49
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 49
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 49
    }
  ]
}