{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEATH",
      "count": 1928
    },
    {
      "term": "DYSPNOEA",
      "count": 1382
    },
    {
      "term": "CHRONIC OBSTRUCTIVE PULMONARY DISEASE",
      "count": 578
    },
    {
      "term": "ASTHMA",
      "count": 574
    },
    {
      "term": "DEVICE DELIVERY SYSTEM ISSUE",
      "count": 513
    },
    {
      "term": "PNEUMONIA",
      "count": 474
    },
    {
      "term": "WHEEZING",
      "count": 468
    },
    {
      "term": "COUGH",
      "count": 456
    },
    {
      "term": "WRONG TECHNIQUE IN DEVICE USAGE PROCESS",
      "count": 441
    },
    {
      "term": "DEVICE USE ISSUE",
      "count": 440
    },
    {
      "term": "DEVICE MALFUNCTION",
      "count": 432
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 381
    },
    {
      "term": "OFF LABEL USE",
      "count": 371
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 356
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 317
    },
    {
      "term": "FATIGUE",
      "count": 286
    },
    {
      "term": "NAUSEA",
      "count": 246
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 222
    },
    {
      "term": "DIARRHOEA",
      "count": 221
    },
    {
      "term": "ASTHENIA",
      "count": 203
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 202
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 202
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 202
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 201
    },
    {
      "term": "VOMITING",
      "count": 200
    },
    {
      "term": "LUNG NEOPLASM MALIGNANT",
      "count": 199
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 198
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED BY DEVICE",
      "count": 192
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 191
    },
    {
      "term": "DIZZINESS",
      "count": 187
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 178
    },
    {
      "term": "PRODUCTIVE COUGH",
      "count": 176
    },
    {
      "term": "FALL",
      "count": 175
    },
    {
      "term": "DRUG DOSE OMISSION BY DEVICE",
      "count": 174
    },
    {
      "term": "PYREXIA",
      "count": 173
    },
    {
      "term": "HEADACHE",
      "count": 171
    },
    {
      "term": "MALAISE",
      "count": 169
    },
    {
      "term": "DEPRESSION",
      "count": 168
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 164
    },
    {
      "term": "OBSTRUCTIVE AIRWAYS DISORDER",
      "count": 163
    },
    {
      "term": "BRONCHIECTASIS",
      "count": 149
    },
    {
      "term": "RHINITIS ALLERGIC",
      "count": 146
    },
    {
      "term": "DYSPHONIA",
      "count": 144
    },
    {
      "term": "HYPOTENSION",
      "count": 143
    },
    {
      "term": "NASAL POLYPS",
      "count": 143
    },
    {
      "term": "COVID-19",
      "count": 142
    },
    {
      "term": "PAIN",
      "count": 140
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 134
    },
    {
      "term": "HYPERTENSION",
      "count": 134
    },
    {
      "term": "ASTHMA-CHRONIC OBSTRUCTIVE PULMONARY DISEASE OVERLAP SYNDROME",
      "count": 129
    },
    {
      "term": "INTENTIONAL DEVICE MISUSE",
      "count": 129
    },
    {
      "term": "PRURITUS",
      "count": 125
    },
    {
      "term": "TOTAL LUNG CAPACITY INCREASED",
      "count": 123
    },
    {
      "term": "LUNG DISORDER",
      "count": 122
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 120
    },
    {
      "term": "SARCOIDOSIS",
      "count": 120
    },
    {
      "term": "CARDIAC MURMUR",
      "count": 119
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 119
    },
    {
      "term": "SLEEP DISORDER DUE TO A GENERAL MEDICAL CONDITION",
      "count": 119
    },
    {
      "term": "ANAEMIA",
      "count": 117
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 116
    },
    {
      "term": "DRUG INTERACTION",
      "count": 113
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 113
    },
    {
      "term": "DYSPNOEA EXERTIONAL",
      "count": 108
    },
    {
      "term": "INSOMNIA",
      "count": 107
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 107
    },
    {
      "term": "CHEST PAIN",
      "count": 106
    },
    {
      "term": "SLEEP APNOEA SYNDROME",
      "count": 106
    },
    {
      "term": "ILLNESS",
      "count": 105
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 105
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 103
    },
    {
      "term": "ARTHRITIS",
      "count": 101
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 98
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 95
    },
    {
      "term": "ANXIETY",
      "count": 94
    },
    {
      "term": "DECREASED APPETITE",
      "count": 93
    },
    {
      "term": "TACHYCARDIA",
      "count": 93
    },
    {
      "term": "TREMOR",
      "count": 92
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 91
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 90
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 90
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 89
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 89
    },
    {
      "term": "PSYCHOTIC DISORDER",
      "count": 89
    },
    {
      "term": "CONSTIPATION",
      "count": 88
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 88
    },
    {
      "term": "CHOLELITHIASIS",
      "count": 86
    },
    {
      "term": "RASH",
      "count": 85
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 84
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 84
    },
    {
      "term": "JAUNDICE CHOLESTATIC",
      "count": 84
    },
    {
      "term": "SEIZURE",
      "count": 84
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 83
    },
    {
      "term": "INFECTION",
      "count": 83
    },
    {
      "term": "SCHIZOPHRENIA",
      "count": 83
    },
    {
      "term": "BRONCHITIS",
      "count": 80
    },
    {
      "term": "BRADYCARDIA",
      "count": 79
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 79
    },
    {
      "term": "GLAUCOMA",
      "count": 79
    },
    {
      "term": "ARTHRALGIA",
      "count": 78
    }
  ]
}