{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 517
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 268
    },
    {
      "term": "OFF LABEL USE",
      "count": 177
    },
    {
      "term": "DEATH",
      "count": 166
    },
    {
      "term": "NEUTROPENIA",
      "count": 162
    },
    {
      "term": "PYREXIA",
      "count": 121
    },
    {
      "term": "COVID-19",
      "count": 92
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 90
    },
    {
      "term": "ANAEMIA",
      "count": 74
    },
    {
      "term": "IMMUNE EFFECTOR CELL-ASSOCIATED NEUROTOXICITY SYNDROME",
      "count": 72
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 66
    },
    {
      "term": "INFECTION",
      "count": 66
    },
    {
      "term": "PNEUMONIA",
      "count": 63
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 56
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 52
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 41
    },
    {
      "term": "TUMOUR FLARE",
      "count": 39
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA RECURRENT",
      "count": 36
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 33
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 32
    },
    {
      "term": "SEPSIS",
      "count": 30
    },
    {
      "term": "COVID-19 PNEUMONIA",
      "count": 28
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA",
      "count": 27
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 26
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 25
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 23
    },
    {
      "term": "DIARRHOEA",
      "count": 23
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 23
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 22
    },
    {
      "term": "MANTLE CELL LYMPHOMA",
      "count": 22
    },
    {
      "term": "HYPOTENSION",
      "count": 21
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 21
    },
    {
      "term": "HEADACHE",
      "count": 20
    },
    {
      "term": "OVERDOSE",
      "count": 20
    },
    {
      "term": "NAUSEA",
      "count": 19
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 19
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 19
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 19
    },
    {
      "term": "BACK PAIN",
      "count": 18
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 17
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 17
    },
    {
      "term": "HYPOGAMMAGLOBULINAEMIA",
      "count": 17
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 17
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 17
    },
    {
      "term": "CHRONIC GRAFT VERSUS HOST DISEASE",
      "count": 16
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 14
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 14
    },
    {
      "term": "FATIGUE",
      "count": 13
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 13
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 13
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 13
    },
    {
      "term": "PAIN",
      "count": 13
    },
    {
      "term": "SYSTEMIC CANDIDA",
      "count": 13
    },
    {
      "term": "URINARY RETENTION",
      "count": 13
    },
    {
      "term": "VIRAL INFECTION",
      "count": 13
    },
    {
      "term": "VOMITING",
      "count": 13
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 13
    },
    {
      "term": "ASTHENIA",
      "count": 12
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 12
    },
    {
      "term": "DYSPNOEA",
      "count": 12
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 12
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 12
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 11
    },
    {
      "term": "DECREASED APPETITE",
      "count": 11
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 11
    },
    {
      "term": "ORGANISING PNEUMONIA",
      "count": 11
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 11
    },
    {
      "term": "RASH",
      "count": 11
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 10
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 10
    },
    {
      "term": "FOLLICULAR LYMPHOMA",
      "count": 10
    },
    {
      "term": "HERPES ZOSTER",
      "count": 10
    },
    {
      "term": "HYPERPYREXIA",
      "count": 10
    },
    {
      "term": "HYPERTRANSAMINASAEMIA",
      "count": 10
    },
    {
      "term": "LEUKOPENIA",
      "count": 10
    },
    {
      "term": "SINUS TACHYCARDIA",
      "count": 10
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 9
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 9
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE IN GASTROINTESTINAL TRACT",
      "count": 9
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 9
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 9
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 9
    },
    {
      "term": "UNDERDOSE",
      "count": 9
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 9
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 9
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 8
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 8
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 8
    },
    {
      "term": "HYPERCALCAEMIA",
      "count": 8
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 8
    },
    {
      "term": "IMMUNE SYSTEM DISORDER",
      "count": 8
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 8
    },
    {
      "term": "JC VIRUS INFECTION",
      "count": 8
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 8
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 8
    },
    {
      "term": "PNEUMONITIS",
      "count": 8
    },
    {
      "term": "PRURITUS",
      "count": 8
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 8
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 8
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 7
    }
  ]
}