{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1270
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 1268
    },
    {
      "term": "PYREXIA",
      "count": 942
    },
    {
      "term": "OFF LABEL USE",
      "count": 914
    },
    {
      "term": "RENAL FAILURE",
      "count": 731
    },
    {
      "term": "DIARRHOEA",
      "count": 601
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 543
    },
    {
      "term": "SEPSIS",
      "count": 535
    },
    {
      "term": "NAUSEA",
      "count": 519
    },
    {
      "term": "HYPOTENSION",
      "count": 513
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 504
    },
    {
      "term": "RASH",
      "count": 503
    },
    {
      "term": "PNEUMONIA",
      "count": 477
    },
    {
      "term": "DYSPNOEA",
      "count": 461
    },
    {
      "term": "FATIGUE",
      "count": 447
    },
    {
      "term": "DRUG INTERACTION",
      "count": 435
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 434
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 433
    },
    {
      "term": "VOMITING",
      "count": 420
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 406
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 403
    },
    {
      "term": "PAIN",
      "count": 393
    },
    {
      "term": "PREMATURE BABY",
      "count": 385
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 383
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 376
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 373
    },
    {
      "term": "ANAEMIA",
      "count": 366
    },
    {
      "term": "DEATH",
      "count": 360
    },
    {
      "term": "NEUTROPENIA",
      "count": 360
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 315
    },
    {
      "term": "PRURITUS",
      "count": 308
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 293
    },
    {
      "term": "PREMATURE DELIVERY",
      "count": 292
    },
    {
      "term": "DIZZINESS",
      "count": 279
    },
    {
      "term": "MALAISE",
      "count": 265
    },
    {
      "term": "RENAL TUBULAR NECROSIS",
      "count": 265
    },
    {
      "term": "ANXIETY",
      "count": 260
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 259
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 255
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 248
    },
    {
      "term": "HEADACHE",
      "count": 244
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 242
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 237
    },
    {
      "term": "END STAGE RENAL DISEASE",
      "count": 232
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 232
    },
    {
      "term": "ARTHRALGIA",
      "count": 229
    },
    {
      "term": "TACHYCARDIA",
      "count": 225
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 223
    },
    {
      "term": "ERYTHEMA",
      "count": 219
    },
    {
      "term": "ASTHENIA",
      "count": 218
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 216
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 213
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 213
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 211
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 211
    },
    {
      "term": "SEIZURE",
      "count": 208
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 207
    },
    {
      "term": "DECREASED APPETITE",
      "count": 203
    },
    {
      "term": "PANCYTOPENIA",
      "count": 203
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 202
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 201
    },
    {
      "term": "EOSINOPHILIA",
      "count": 197
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 194
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 194
    },
    {
      "term": "COUGH",
      "count": 191
    },
    {
      "term": "HYPERTENSION",
      "count": 188
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 188
    },
    {
      "term": "CHEST PAIN",
      "count": 184
    },
    {
      "term": "OVERDOSE",
      "count": 184
    },
    {
      "term": "INFECTION",
      "count": 183
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 182
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 176
    },
    {
      "term": "CELLULITIS",
      "count": 175
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 173
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 173
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 171
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 170
    },
    {
      "term": "CARDIAC ARREST",
      "count": 169
    },
    {
      "term": "LEUKOPENIA",
      "count": 168
    },
    {
      "term": "CHILLS",
      "count": 166
    },
    {
      "term": "ALOPECIA",
      "count": 162
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 158
    },
    {
      "term": "RENAL INJURY",
      "count": 158
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 157
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 157
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 156
    },
    {
      "term": "DEHYDRATION",
      "count": 155
    },
    {
      "term": "BACK PAIN",
      "count": 154
    },
    {
      "term": "BALANCE DISORDER",
      "count": 154
    },
    {
      "term": "INJURY",
      "count": 154
    },
    {
      "term": "FALL",
      "count": 149
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 149
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 149
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 149
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 145
    },
    {
      "term": "URTICARIA",
      "count": 145
    },
    {
      "term": "PERITONITIS",
      "count": 144
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 143
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 142
    },
    {
      "term": "DEPRESSION",
      "count": 141
    }
  ]
}